| Protein: | CDC12 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 407 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CDC12.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [3..383] | [111..482] |
|
|
0.0 | [3..407] | [18..411] |
|
|
0.0 | [4..407] | [19..411] |
|
|
3.0E-98 | [14..363] | [124..474] |
|
|
1.0E-96 | [9..398] | [7..389] |
|
Region A: Residues: [1-274] |
1 11 21 31 41 51
| | | | | |
1 MSAATATAAP VPPPVGISNL PNQRYKIVNE EGGTFTVMLC GESGLGKTTF INTLFQTVLK 60
61 RADGQQHRQE PIRKTVEIDI TRALLEEKHF ELRVNVIDTP GFGDNVNNNK AWQPLVDFID 120
121 DQHDSYMRQE QQPYRTKKFD LRVHAVLYFI RPTGHGLKPI DIETMKRLST RANLIPVIAK 180
181 ADTLTAQELQ QFKSRIRQVI EAQEIRIFTP PLDADSKEDA KSGSNPDSAA VEHARQLIEA 240
241 MPFAIVGSEK KFDNGQGTQV VARKYPWGLV EIEN
|
| Detection Method: |  |
| Confidence: | 19.30103 |
| Match: | 1egaA_ |
| Description: | GTPase Era, N-terminal domain; GTPase Era C-terminal domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [275-407] |
1 11 21 31 41 51
| | | | | |
1 DSHCDFRKLR ALLLRTYLLD LISTTQEMHY ETYRRLRLEG HENTGEGNED FTLPAIAPAR 60
61 KLSHNPRYKE EENALKKYFT DQVKAEEQRF RQWEQNIVNE RIRLNGDLEE IQGKVKKLEE 120
121 QVKSLQVKKS HLK
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.829 | 0.080 | axial cellular bud site selection | a.7.1 | Spectrin repeat |
| View | Download | 0.927 | 0.025 | axial cellular bud site selection | a.7.4 | Smac/diablo |
| View | Download | 0.819 | 0.022 | axial cellular bud site selection | a.63.1 | Apolipophorin-III |
| View | Download | 0.759 | N/A | N/A | a.63.1 | Apolipophorin-III |
| View | Download | 0.706 | N/A | N/A | a.7.4 | Smac/diablo |
| View | Download | 0.705 | N/A | N/A | a.7.4 | Smac/diablo |
| View | Download | 0.690 | N/A | N/A | a.7.5 | Tubulin chaperone cofactor A |
| View | Download | 0.678 | N/A | N/A | a.24.1 | Apolipoprotein |
| View | Download | 0.676 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.634 | N/A | N/A | a.2.5 | Prefoldin |
| View | Download | 0.600 | N/A | N/A | a.7.4 | Smac/diablo |
| View | Download | 0.586 | N/A | N/A | a.7.4 | Smac/diablo |
| View | Download | 0.571 | N/A | N/A | a.47.2 | t-snare proteins |
| View | Download | 0.559 | N/A | N/A | a.7.4 | Smac/diablo |
| View | Download | 0.559 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.550 | N/A | N/A | a.7.5 | Tubulin chaperone cofactor A |
| View | Download | 0.540 | N/A | N/A | a.47.2 | t-snare proteins |
| View | Download | 0.538 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.524 | N/A | N/A | a.7.4 | Smac/diablo |
| View | Download | 0.503 | N/A | N/A | a.25.1 | Ferritin-like |
| View | Download | 0.495 | N/A | N/A | a.2.7 | tRNA-binding arm |
| View | Download | 0.477 | N/A | N/A | a.24.1 | Apolipoprotein |
| View | Download | 0.476 | N/A | N/A | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.462 | N/A | N/A | d.67.3 | Ribosome recycling factor, RRF |
| View | Download | 0.450 | N/A | N/A | d.6.1 | Prion-like |
| View | Download | 0.438 | N/A | N/A | f.16.1 | Gated mechanosensitive channel |
| View | Download | 0.434 | N/A | N/A | a.7.4 | Smac/diablo |
| View | Download | 0.430 | N/A | N/A | a.7.4 | Smac/diablo |
| View | Download | 0.424 | N/A | N/A | a.7.7 | BAG domain |
| View | Download | 0.419 | N/A | N/A | a.7.4 | Smac/diablo |
| View | Download | 0.414 | N/A | N/A | a.24.3 | Cytochromes |
| View | Download | 0.402 | N/A | N/A | c.23.1 | CheY-like |
| View | Download | 0.395 | N/A | N/A | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.390 | N/A | N/A | a.2.5 | Prefoldin |
| View | Download | 0.381 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.380 | N/A | N/A | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.377 | N/A | N/A | a.24.1 | Apolipoprotein |
| View | Download | 0.374 | N/A | N/A | a.47.1 | STAT |
| View | Download | 0.368 | N/A | N/A | c.23.1 | CheY-like |
| View | Download | 0.368 | N/A | N/A | e.20.1 | Heat shock protein 70kD (HSP70), C-terminal substrate-binding fragment |
| View | Download | 0.368 | N/A | N/A | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.360 | N/A | N/A | a.24.1 | Apolipoprotein |
| View | Download | 0.346 | N/A | N/A | a.118.1 | ARM repeat |
| View | Download | 0.345 | N/A | N/A | a.24.1 | Apolipoprotein |
| View | Download | 0.344 | N/A | N/A | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
| View | Download | 0.340 | N/A | N/A | a.7.5 | Tubulin chaperone cofactor A |
| View | Download | 0.340 | N/A | N/A | a.7.7 | BAG domain |
| View | Download | 0.339 | N/A | N/A | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.338 | N/A | N/A | f.17.2 | Cytochrome c oxidase subunit II-like, transmembrane region |
| View | Download | 0.336 | N/A | N/A | a.47.2 | t-snare proteins |
| View | Download | 0.333 | N/A | N/A | a.7.5 | Tubulin chaperone cofactor A |
| View | Download | 0.329 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.329 | N/A | N/A | d.67.3 | Ribosome recycling factor, RRF |
| View | Download | 0.325 | N/A | N/A | a.156.1 | S13-like H2TH domain |
| View | Download | 0.324 | N/A | N/A | a.2.5 | Prefoldin |
| View | Download | 0.319 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.310 | N/A | N/A | a.24.1 | Apolipoprotein |
| View | Download | 0.308 | N/A | N/A | a.7.4 | Smac/diablo |
| View | Download | 0.308 | N/A | N/A | a.47.1 | STAT |
| View | Download | 0.306 | N/A | N/A | a.47.2 | t-snare proteins |
| View | Download | 0.306 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.301 | N/A | N/A | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.300 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.299 | N/A | N/A | a.7.4 | Smac/diablo |
| View | Download | 0.297 | N/A | N/A | a.156.1 | S13-like H2TH domain |
| View | Download | 0.294 | N/A | N/A | a.24.3 | Cytochromes |
| View | Download | 0.293 | N/A | N/A | a.7.5 | Tubulin chaperone cofactor A |
| View | Download | 0.291 | N/A | N/A | a.7.7 | BAG domain |
| View | Download | 0.286 | N/A | N/A | f.17.2 | Cytochrome c oxidase subunit II-like, transmembrane region |
| View | Download | 0.285 | N/A | N/A | a.47.2 | t-snare proteins |
| View | Download | 0.283 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.283 | N/A | N/A | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.281 | N/A | N/A | a.25.1 | Ferritin-like |
| View | Download | 0.279 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.279 | N/A | N/A | c.23.1 | CheY-like |
| View | Download | 0.278 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.276 | N/A | N/A | a.172.1 | Helical scaffold and wing domains of SecA |
| View | Download | 0.275 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.274 | N/A | N/A | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.273 | N/A | N/A | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.272 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.272 | N/A | N/A | a.7.7 | BAG domain |
| View | Download | 0.271 | N/A | N/A | a.24.14 | FAT domain of focal adhesion kinase |
| View | Download | 0.270 | N/A | N/A | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.270 | N/A | N/A | d.198.1 | Type III secretory system chaperone |
| View | Download | 0.269 | N/A | N/A | a.38.1 | Helix-loop-helix DNA-binding domain |
| View | Download | 0.269 | N/A | N/A | a.63.1 | Apolipophorin-III |
| View | Download | 0.267 | N/A | N/A | c.23.1 | CheY-like |
| View | Download | 0.266 | N/A | N/A | a.47.2 | t-snare proteins |
| View | Download | 0.263 | N/A | N/A | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.262 | N/A | N/A | a.24.1 | Apolipoprotein |
| View | Download | 0.260 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.258 | N/A | N/A | a.24.12 | Outer surface protein C (OspC) |
| View | Download | 0.258 | N/A | N/A | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.255 | N/A | N/A | a.172.1 | Helical scaffold and wing domains of SecA |
| View | Download | 0.251 | N/A | N/A | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.251 | N/A | N/A | a.24.14 | FAT domain of focal adhesion kinase |
| View | Download | 0.249 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.249 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.249 | N/A | N/A | a.25.1 | Ferritin-like |
| View | Download | 0.248 | N/A | N/A | a.118.1 | ARM repeat |
| View | Download | 0.244 | N/A | N/A | a.38.1 | Helix-loop-helix DNA-binding domain |
| View | Download | 0.244 | N/A | N/A | f.17.1 | F1F0 ATP synthase subunit C |
| View | Download | 0.242 | N/A | N/A | a.7.4 | Smac/diablo |
| View | Download | 0.241 | N/A | N/A | a.2.7 | tRNA-binding arm |
| View | Download | 0.241 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.240 | N/A | N/A | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.239 | N/A | N/A | a.38.1 | Helix-loop-helix DNA-binding domain |
| View | Download | 0.239 | N/A | N/A | c.49.2 | ATP synthase (F1-ATPase), gamma subunit |
| View | Download | 0.239 | N/A | N/A | a.2.5 | Prefoldin |
| View | Download | 0.237 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.237 | N/A | N/A | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.236 | N/A | N/A | a.2.7 | tRNA-binding arm |
| View | Download | 0.236 | N/A | N/A | c.49.2 | ATP synthase (F1-ATPase), gamma subunit |
| View | Download | 0.236 | N/A | N/A | a.24.14 | FAT domain of focal adhesion kinase |
| View | Download | 0.235 | N/A | N/A | a.7.5 | Tubulin chaperone cofactor A |
| View | Download | 0.232 | N/A | N/A | a.2.5 | Prefoldin |
| View | Download | 0.232 | N/A | N/A | a.118.1 | ARM repeat |
| View | Download | 0.231 | N/A | N/A | a.63.1 | Apolipophorin-III |
| View | Download | 0.231 | N/A | N/A | f.15.1 | Small-conductance potassium channel |
| View | Download | 0.229 | N/A | N/A | a.24.3 | Cytochromes |
| View | Download | 0.229 | N/A | N/A | a.7.7 | BAG domain |
| View | Download | 0.229 | N/A | N/A | a.24.14 | FAT domain of focal adhesion kinase |
| View | Download | 0.225 | N/A | N/A | a.48.2 | Transferrin receptor ectodomain, C-terminal domain |
| View | Download | 0.225 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.222 | N/A | N/A | a.7.7 | BAG domain |
| View | Download | 0.221 | N/A | N/A | a.38.1 | Helix-loop-helix DNA-binding domain |
| View | Download | 0.220 | N/A | N/A | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.220 | N/A | N/A | f.17.1 | F1F0 ATP synthase subunit C |
| View | Download | 0.219 | N/A | N/A | d.67.3 | Ribosome recycling factor, RRF |
| View | Download | 0.217 | N/A | N/A | f.15.1 | Small-conductance potassium channel |
| View | Download | 0.217 | N/A | N/A | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.217 | N/A | N/A | a.25.1 | Ferritin-like |
| View | Download | 0.215 | N/A | N/A | a.7.5 | Tubulin chaperone cofactor A |
| View | Download | 0.213 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.213 | N/A | N/A | a.7.4 | Smac/diablo |
| View | Download | 0.212 | N/A | N/A | a.24.1 | Apolipoprotein |
| View | Download | 0.211 | N/A | N/A | a.7.5 | Tubulin chaperone cofactor A |
| View | Download | 0.211 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.209 | N/A | N/A | a.24.4 | Hemerythrin |
| View | Download | 0.209 | N/A | N/A | f.16.1 | Gated mechanosensitive channel |
| View | Download | 0.208 | N/A | N/A | a.156.1 | S13-like H2TH domain |
| View | Download | 0.208 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.206 | N/A | N/A | a.7.4 | Smac/diablo |
| View | Download | 0.205 | N/A | N/A | a.172.1 | Helical scaffold and wing domains of SecA |
| View | Download | 0.203 | N/A | N/A | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.202 | N/A | N/A | c.23.1 | CheY-like |
| View | Download | 0.201 | N/A | N/A | a.7.5 | Tubulin chaperone cofactor A |
| View | Download | 0.201 | N/A | N/A | a.47.2 | t-snare proteins |
| View | Download | 0.201 | N/A | N/A | a.7.1 | Spectrin repeat |
