YRC Public Data Repository - Protein Structure Prediction

Protein:	GEP4
Organism:	Saccharomyces cerevisiae
Length:	185 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GEP4.

Description	E-value	Query Range	Subject Range
gi\|190405879 - gi\|190405879\|gb\|EDV09146.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a] GEP4 - Protein of unknown function required for respiratory growth; detected in highly purified mitochondri... GEP4_YEAST - Phosphatidylglycerophosphatase GEP4, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 /...	1.0E-50	[1..185]	[1..185]
gi\|85100264 - gi\|85100264\|ref\|XP_960928.1\| hypothetical protein NCU01371 [Neurospora crassa OR74A] gi\|28922461, gi\|... - gi\|32412768\|ref\|XP_326864.1\| hypothetical protein ( (AL353822) conserved hypothetical protein [Neuro...	2.0E-49	[1..183]	[6..203]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	2.0E-46	[1..170]	[6..188]
GEP4_SCHPO - Probable phosphatidylglycerophosphatase, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / AT... SPCC645.02 - conserved protein (fungal and plant)	4.0E-39	[1..175]	[3..188]
gi\|25356478 - pir\|\|B83815 hypothetical protein BH1322 [imported] - Bacillus halodurans (strain C-125) gi\|10173938, gi\|... - gi\|15613885\|ref\|NP_242188.1\| hypothetical protein BH1322 [Bacillus halodurans C-125], gi\|10173938\|db...	6.0E-35	[17..183]	[3..161]
gi\|94541398, gi\|... - gi\|94987890\|ref\|YP_595991.1\| putative lipase [Streptococcus pyogenes MGAS9429], gi\|94541398\|gb\|ABF31... gi\|94547158, gi\|... - gi\|94993650\|ref\|YP_601748.1\| Putative lipase [Streptococcus pyogenes MGAS10750], gi\|94547158\|gb\|ABF3... gi\|28896549, gi\|... - gi\|28896549\|ref\|NP_802899.1\| hypothetical protein SPs1637 [Streptococcus pyogenes SSI-1], gi\|2881180... gi\|15674472, gi\|... - gi\|15674472\|ref\|NP_268646.1\| hypothetical protein SPy_0305 [Streptococcus pyogenes M1 GAS], gi\|13621... gi\|19747539, gi\|... - gi\|19747539\|gb\|AAL97062.1\| conserved hypothetical protein [Streptococcus pyogenes MGAS8232], gi\|1974... gi\|71902918, gi\|... - gi\|71902918\|ref\|YP_279721.1\| putative lipase [Streptococcus pyogenes MGAS6180], gi\|71802013\|gb\|AAX71... gi\|209558819, gi... - gi\|209558819\|ref\|YP_002285291.1\| hypothetical protein Spy49_0257 [Streptococcus pyogenes NZ131], gi\|... gi\|21903944, gi\|... - gi\|21909759\|ref\|NP_664027.1\| hypothetical protein SpyM3_0223 [Streptococcus pyogenes MGAS315], gi\|21... gi\|71910074, gi\|... - gi\|71910074\|ref\|YP_281624.1\| putative lipase [Streptococcus pyogenes MGAS5005], gi\|71852856\|gb\|AAZ50... gi\|94991775, gi\|... - gi\|94991775\|ref\|YP_599874.1\| putative lipase [Streptococcus pyogenes MGAS2096], gi\|94545283\|gb\|ABF35... gi\|56807735 - gi\|56807735\|ref\|ZP_00365601.1\| COG2179: Predicted hydrolase of the HAD superfamily [Streptococcus py...	1.0E-33	[20..183]	[26..181]
gi\|25356476 - pir\|\|E86902 hypothetical protein yxaC [imported] - Lactococcus lactis subsp. lactis (strain IL1403) gi\|15674203, gi\|... - gi\|15674203\|ref\|NP_268378.1\| hypothetical protein L86471 [Lactococcus lactis subsp. lactis Il1403], ...	7.0E-33	[20..183]	[7..162]
gi\|25356485 - pir\|\|A98071 conserved hypothetical protein spr1595 [imported] - Streptococcus pneumoniae (strain R6) gi\|15903637, gi\|... - gi\|15903637\|ref\|NP_359187.1\| hypothetical protein spr1595 [Streptococcus pneumoniae R6], gi\|15459262...	3.0E-32	[21..182]	[29..182]
gi\|148989412, gi... - gi\|148989412\|ref\|ZP_01820780.1\| hypothetical protein CGSSp6BS73_07939 [Streptococcus pneumoniae SP6-... gi\|237649162 - gi\|237649162\|ref\|ZP_04523414.1\| hypothetical protein SpneC1_00150 [Streptococcus pneumoniae CCRI 197... gi\|147923482, gi... - gi\|148984193\|ref\|ZP_01817488.1\| hypothetical protein CGSSp3BS71_03192 [Streptococcus pneumoniae SP3-... gi\|237820722 - gi\|237820722\|ref\|ZP_04596567.1\| hypothetical protein SpneC19_00050 [Streptococcus pneumoniae CCRI 19... gi\|168486389, gi... - gi\|183570589\|gb\|EDT91117.1\| had superfamily (subfamily iiia) phosphatase [Streptococcus pneumoniae C... gi\|168483289, gi... - gi\|172043178\|gb\|EDT51224.1\| had superfamily (subfamily iiia) phosphatase [Streptococcus pneumoniae C... gi\|168491367, gi... - gi\|183574235\|gb\|EDT94763.1\| had superfamily (subfamily iiia) phosphatase [Streptococcus pneumoniae C... gi\|183572691, gi... - gi\|183572691\|gb\|EDT93219.1\| had superfamily (subfamily iiia) phosphatase [Streptococcus pneumoniae S... gi\|149020833, gi... - gi\|149020833\|ref\|ZP_01835362.1\| hypothetical protein CGSSp23BS72_02309 [Streptococcus pneumoniae SP2... gi\|149011380, gi... - gi\|149011380\|ref\|ZP_01832627.1\| hypothetical protein CGSSp19BS75_08217 [Streptococcus pneumoniae SP1... gi\|147761880, gi... - gi\|149006582\|ref\|ZP_01830281.1\| hypothetical protein CGSSp18BS74_02296 [Streptococcus pneumoniae SP1... gi\|147759865, gi... - gi\|149002056\|ref\|ZP_01827010.1\| hypothetical protein CGSSp14BS69_10106 [Streptococcus pneumoniae SP1... gi\|148997806, gi... - gi\|148997806\|ref\|ZP_01825370.1\| hypothetical protein CGSSp11BS70_02824 [Streptococcus pneumoniae SP1... gi\|25356481 - pir\|\|A95204 conserved hypothetical protein SP1750 [imported] - Streptococcus pneumoniae (strain TIGR... gi\|183578701, gi... - gi\|183578701\|gb\|EDT99229.1\| had superfamily (subfamily iiia) phosphatase [Streptococcus pneumoniae M... gi\|66877182, gi\|... - gi\|66877182\|ref\|ZP_00402814.1\| COG2179: Predicted hydrolase of the HAD superfamily [Streptococcus pn... gi\|183576377, gi... - gi\|183576377\|gb\|EDT96905.1\| had superfamily (subfamily iiia) phosphatase [Streptococcus pneumoniae C... gi\|194358303, gi... - gi\|194398636\|ref\|YP_002038360.1\| had-superfamily hydrolase (subfamily IIIa) phosphatase [Streptococc... gi\|168996020, gi... - gi\|169833518\|ref\|YP_001695125.1\| HAD family phosphatase [Streptococcus pneumoniae Hungary19A-6], gi\|... gi\|225855181, gi... - gi\|225855181\|ref\|YP_002736693.1\| had superfamily (subfamily iiia) phosphatase [Streptococcus pneumon... gi\|221232485, gi... - gi\|221232485\|ref\|YP_002511638.1\| putative hydrolase [Streptococcus pneumoniae ATCC 700669], gi\|22067... gi\|225857362, gi... - gi\|225857362\|ref\|YP_002738873.1\| had superfamily (subfamily iiia) phosphatase [Streptococcus pneumon... gi\|225859502, gi... - gi\|225859502\|ref\|YP_002741012.1\| had superfamily (subfamily iiia) phosphatase [Streptococcus pneumon... gi\|225727376, gi... - gi\|225861572\|ref\|YP_002743081.1\| had superfamily (subfamily iiia) phosphatase [Streptococcus pneumon...	6.0E-32	[20..182]	[7..161]
YQEG_BACSU - Uncharacterized protein yqeG OS=Bacillus subtilis GN=yqeG PE=4 SV=1 gi\|221319739 - gi\|221319739\|ref\|ZP_03601033.1\| hypothetical protein BsubsJ_13878 [Bacillus subtilis subsp. subtilis... gi\|221314817 - gi\|221314817\|ref\|ZP_03596622.1\| hypothetical protein BsubsN3_13952 [Bacillus subtilis subsp. subtili... YQEG_BACSU - Uncharacterized protein YqeG OS=Bacillus subtilis (strain 168) GN=yqeG PE=4 SV=1 gi\|221324017 - gi\|221324017\|ref\|ZP_03605311.1\| hypothetical protein BsubsS_14007 [Bacillus subtilis subsp. subtilis...	2.0E-31	[17..183]	[4..162]

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Predicted Domain #1

Region A:
Residues: [1-185]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNISGTLNTL RLLYNPSLCK PSLVVPTFND LPIPIHDSIK AVVLDKDNCI AFPHDDKIWP  60
   61 DYLQHWETLR SKYSNKALLI VSNTAGSNSD KDYSQAKLLE DKTGIPVLRH STKKPGCHNE 120
  121 ILDYFYRNKT ITNPKEVAVV GDRLFTDILM ANLMGSYGVW IRDGVKVSAN PLSKFEKKLY 180
  181 NFLGF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	6.69897
Match:	1zrm__
Description:	L-2-Haloacid dehalogenase, HAD
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits