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View Structure Prediction Details

Protein: KSP1
Organism: Saccharomyces cerevisiae
Length: 1029 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KSP1.

Description E-value Query
Range
Subject
Range
KSP1_YEAST - Serine/threonine-protein kinase KSP1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KSP...
KSP1 - Ser/thr protein kinase; nuclear translocation required for haploid filamentous growth; regulates fil...
gi|151944029 - gi|151944029|gb|EDN62322.1| conserved protein [Saccharomyces cerevisiae YJM789]
0.0 [1..1029] [1..1029]
CDPKL_ARATH - Calcium-dependent protein kinase 21 OS=Arabidopsis thaliana GN=CPK21 PE=1 SV=1
0.0 [11..545] [1..522]
gi|13561063 - gi|13561063|emb|CAA65500.1| protein kinase [Medicago sativa]
0.0 [11..545] [1..537]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [22..545] [18..533]
CDPK2_ORYSJ - Calcium-dependent protein kinase isoform 2 OS=Oryza sativa subsp. japonica GN=CPK2 PE=2 SV=2
CDPK2_ORYSA - Calcium-dependent protein kinase, isoform 2 (EC 2.7.11.1) (CDPK 2) - Oryza sativa (Rice)
0.0 [11..542] [1..524]

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Predicted Domain #1
Region A:
Residues: [1-81]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLDYEIYKE GGILNNRYQK IEDISEGSYG YVSLAKDVRE KRLVAVKYIF KLEDDGQYDG  60
   61 PQDDENDCDS SDCDDDEDTK V

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.0
Match: 1gxcA_
Description: Chk2 kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.47621789723131 bayes_pls_golite062009
protein binding 2.22336167249906 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [82-308]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTDRHENENG NASSNNGSSR EKKHNLYKHK KSLISSKVKS RLSNNICLEA MYEVDIQTKI  60
   61 GRHQNIAALL DFFDSYIIME YCSGGDLYEA IKADAVPKKT KSITHIITQI MDAIEYVHNK 120
  121 GIYHRDIKPE NILISGIDWT IKLTDWGLAT TDKTSMDRNV GSERYMSPEL FDSNLDIKER 180
  181 KEPYDCAKVD LWAMGIVFLN IVFHKNPFSI ANQSDKSFCY FAANREA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 95.228787
Match: 1b6cB_
Description: Type I TGF-beta receptor R4
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [309-391]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LFDVFSTMAY DFFQVLRYSL TIDPANRDLK MMRTELQNLS EYTLDDEYYN NLDEGYEETM  60
   61 IDGLPPQPVP PSSAPVSLPT PIS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 273.9897
Match: 1a06__
Description: Calmodulin-dependent protein kinase
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [392-463]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSNKQHMPEF KKDFNFNNVN ERKRSDVSQN QNVASGFFKK PSTQQQKFFN QGYNTTLSTH  60
   61 ERAKSAPKFK FK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.30103
Match: 1iq5A_
Description: Calmodulin
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [464-556]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KRNKYGRTDN QFSKPVNIED RKKSKILKKS RKPLGIPTPN THMNNFFHDY KARDEFNTRD  60
   61 FFTPPSVQHR YMEGFSNNNN KQYRQNRNYN NNN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.30103
Match: 1iq5A_
Description: Calmodulin
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [557-1029]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNSNNNHGSN YNNFNNGNSY IKGWNKNFNK YRRPSSSSYT GKSPLSRYNM SYNHNNNSSI  60
   61 NGYARRGSTT TVQHSPGAYI PPNARNHHVS PTNQFLRVPQ STAPDISTVL GGKPSYQEHY 120
  121 TQDSMDSEGD HDSDDVLFTL EEGDHDFVNG MDNLSINDHL PHTTVGSHNE VFVHASTNHN 180
  181 NNGNNNHIDT NSTTNQYHRQ YIPPPLTTSL HINNNNNESN ELPDLLKSPA SSEAHLNLSS 240
  241 GPIDPILTGN IGNRYSHSSD SKELEQERRL SMEQKFKNGV YVPPHHRKSF NLGTQVPPMN 300
  301 MKTSNEATLS VSHNSVNFGG SYNSRRSSAN ESNPLHMNKA LEKLSSSPGA KSSFVGFPKP 360
  361 LLPRNHSSTT IALQNEDVFA DSNNDAIIFE DEEYEGESDK MAHGKMEGGD NESSSTSPDE 420
  421 RQIFGPYEIY AQTFAGSTHD KKLGAGRKTS IQDEMVGSLE QYKNNWLILQ QQD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle