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View Structure Prediction Details

Protein: PTC7
Organism: Saccharomyces cerevisiae
Length: 374 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PTC7.

Description E-value Query
Range
Subject
Range
gi|190405858 - gi|190405858|gb|EDV09125.1| type 2C protein Phosphatase [Saccharomyces cerevisiae RM11-1a]
gi|207344675 - gi|207344675|gb|EDZ71739.1| YHR076Wp-like protein [Saccharomyces cerevisiae AWRI1631]
PTC7 - Type 2C protein phosphatase; YHR076W is alternatively spliced to create two mRNA isoforms; protein f...
3.0E-87 [1..374] [1..374]
P2C77_ARATH - Protein phosphatase 2C 77 OS=Arabidopsis thaliana GN=ABI2 PE=1 SV=1
7.0E-64 [36..373] [58..411]
gi|7768151 - gi|7768151|emb|CAB90633.1| protein phpsphatase 2C (PP2C) [Fagus sylvatica]
7.0E-59 [66..373] [96..407]
PPM1A_RABIT - Protein phosphatase 1A OS=Oryctolagus cuniculus GN=PPM1A PE=2 SV=1
1.0E-55 [106..371] [22..289]
CCDS9744.1_1 - null
PPM1A - protein phosphatase, Mg2+/Mn2+ dependent, 1A
gi|114653343, gi... - gi|114653347|ref|XP_509986.2| PREDICTED: hypothetical protein LOC452950 isoform 9 [Pan troglodytes],...
gi|109083826, gi... - gi|109083828|ref|XP_001096358.1| PREDICTED: similar to protein phosphatase 1A isoform 1 isoform 5 [M...
gi|123996549, gi... - gi|168279063|dbj|BAG11411.1| protein phosphatase 1A [synthetic construct], gi|123996549|gb|ABM85876....
2.0E-55 [106..371] [22..289]
PPM1A_RAT - Protein phosphatase 1A OS=Rattus norvegicus GN=Ppm1a PE=1 SV=1
2.0E-55 [106..371] [22..289]

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Predicted Domain #1
Region A:
Residues: [1-82]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFANVGFRTL RVSRGPLYGM FIVLFIGVLI AKFAGQMLID SETNFSHIIG SCSQIISFSK  60
   61 RTFYSSAKSG YQSNNSHGDA YS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.691 a.3.1 Cytochrome c
View Download 0.633 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.589 a.21.1 HMG-box
View Download 0.584 a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.400 a.77.1 DEATH domain
View Download 0.392 a.24.3 Cytochromes
View Download 0.383 a.179.1 Replisome organizer (g39p helicase loader/inhibitor protein)
View Download 0.357 f.17.1 F1F0 ATP synthase subunit C
View Download 0.357 a.112.1 Description not found.
View Download 0.321 a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.315 a.4.5 "Winged helix" DNA-binding domain
View Download 0.313 a.24.17 Group V grass pollen allergen
View Download 0.311 d.58.5 GlnB-like
View Download 0.306 a.4.12 TrpR-like
View Download 0.304 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.278 a.4.5 "Winged helix" DNA-binding domain
View Download 0.273 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.273 a.151.1 Glutamyl tRNA-reductase dimerization domain
View Download 0.272 a.16.1 S15/NS1 RNA-binding domain
View Download 0.271 a.74.1 Cyclin-like
View Download 0.260 a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.242 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.242 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.238 a.24.4 Hemerythrin
View Download 0.229 a.4.1 Homeodomain-like
View Download 0.225 a.74.1 Cyclin-like
View Download 0.224 a.11.1 Acyl-CoA binding protein
View Download 0.223 a.101.1 Uteroglobin-like
View Download 0.220 a.55.1 IHF-like DNA-binding proteins
View Download 0.218 a.21.1 HMG-box
View Download 0.216 a.69.1 C-terminal domain of alpha and beta subunits of F1 ATP synthase
View Download 0.214 a.3.1 Cytochrome c
View Download 0.214 a.36.1 Signal peptide-binding domain
View Download 0.211 a.40.1 Calponin-homology domain, CH-domain
View Download 0.210 a.26.1 4-helical cytokines
View Download 0.209 a.64.1 Saposin
View Download 0.209 a.39.1 EF-hand
View Download 0.207 a.51.1 Cytochrome c oxidase subunit h
View Download 0.204 a.74.1 Cyclin-like

Predicted Domain #2
Region A:
Residues: [83-374]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGSQSGPFTY KTAVAFQPKD RDDLIYQKLK DSIRSPTGED NYFVTSNNVH DIFAGVADGV  60
   61 GGWAEHGYDS SAISRELCKK MDEISTALAE NSSKETLLTP KKIIGAAYAK IRDEKVVKVG 120
  121 GTTAIVAHFP SNGKLEVANL GDSWCGVFRD SKLVFQTKFQ TVGFNAPYQL SIIPEEMLKE 180
  181 AERRGSKYIL NTPRDADEYS FQLKKKDIII LATDGVTDNI ATDDIELFLK DNAARTNDEL 240
  241 QLLSQKFVDN VVSLSKDPNY PSVFAQEISK LTGKNYSGGK EDDITVVVVR VD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.30103
Match: 1a6q__
Description: Protein serine/threonine phosphatase 2C, C-terminal domain; Protein serine/threonine phosphatase 2C, catalytic domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle