YRC Public Data Repository - Protein Structure Prediction

Protein:	DOG2
Organism:	Saccharomyces cerevisiae
Length:	246 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DOG2.

Description	E-value	Query Range	Subject Range
DOG2_YEAST - 2-deoxyglucose-6-phosphate phosphatase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN... DOG2 - 2-deoxyglucose-6-phosphate phosphatase, member of a family of low molecular weight phosphatases, sim...	4.0E-50	[1..246]	[1..246]
GPH_HAEIN - Phosphoglycolate phosphatase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) G... GPH_HAEIN - Phosphoglycolate phosphatase OS=Haemophilus influenzae GN=gph PE=3 SV=1	1.0E-38	[5..229]	[4..224]
GPH_PASMU - Phosphoglycolate phosphatase OS=Pasteurella multocida (strain Pm70) GN=gph PE=3 SV=1 GPH_PASMU - Phosphoglycolate phosphatase OS=Pasteurella multocida GN=gph PE=3 SV=1	3.0E-37	[1..230]	[1..224]
G3PP_PYRAB - Glyceraldehyde 3-phosphate phosphatase OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=PYRAB05140 PE=3 ... YB10_PYRAB - Uncharacterized HAD-hydrolase PYRAB05140 OS=Pyrococcus abyssi GN=PYRAB05140 PE=3 SV=1	2.0E-36	[6..241]	[2..236]
EG11871 - phosphoglycolate phosphatase / Phosphoglycolate phosphatase; in dam operon; involved in degradation ... gi\|194421583, gi... - gi\|83585104\|ref\|ZP_00923756.1\| COG0546: Predicted phosphatases [Escherichia coli 101-1], gi\|19443949... gi\|75211751, gi\|... - gi\|75211751\|ref\|ZP_00711815.1\| COG0546: Predicted phosphatases [Escherichia coli B171], gi\|194426923... gi\|238902476, gi... - gi\|238902476\|ref\|YP_002928272.1\| phosphoglycolate phosphatase [Escherichia coli BW2952], gi\|23886204... gi\|191167879, gi... - gi\|75228961\|ref\|ZP_00715553.1\| COG0546: Predicted phosphatases [Escherichia coli B7A], gi\|191167879\|... gi\|251786638, gi... - gi\|251786638\|ref\|YP_003000942.1\| hypothetical protein B21_03189 [Escherichia coli BL21], gi\|24237891... gi\|193061794, gi... - gi\|75260326\|ref\|ZP_00731594.1\| COG0546: Predicted phosphatases [Escherichia coli E22], gi\|193061794\|... gi\|253771788, gi... - gi\|254290063\|ref\|YP_003055811.1\| phosphoglycolate phosphatase [Escherichia coli BL21(DE3)], gi\|25397... gi\|89110625, gi\|... - gi\|89110625\|ref\|AP_004405.1\| phosphoglycolate phosphatase [Escherichia coli str. K-12 substr. W3110]... gi\|253975214, gi... - gi\|254163313\|ref\|YP_003046421.1\| phosphoglycolate phosphatase [Escherichia coli B str. REL606], gi\|2... GPH_ECOLI - Phosphoglycolate phosphatase (EC 3.1.3.18) (PGPase) (PGP) - Escherichia coli gi\|170082902, gi... - gi\|170082902\|ref\|YP_001732222.1\| phosphoglycolate phosphatase [Escherichia coli str. K-12 substr. DH... EG11871 - phosphoglycolate phosphatase / Phosphoglycolate phosphatase; in dam operon; involved in degradation ...	1.0E-35	[6..229]	[7..239]
Y1777_PYRFU, YH7... - (Q8U040) Putative HAD-hydrolase PF1777 (EC 3.-.-.-), Uncharacterized HAD-hydrolase PF1777 OS=Pyrococ... G3PP_PYRFU - Glyceraldehyde 3-phosphate phosphatase OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 84...	1.0E-35	[4..241]	[2..238]
YG55_PYRHO, Y165... - (O59346) Putative HAD-hydrolase PH1655 (EC 3.-.-.-), Uncharacterized HAD-hydrolase PH1655 OS=Pyrococ... G3PP_PYRHO - Glyceraldehyde 3-phosphate phosphatase OS=Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JC...	1.0E-35	[6..242]	[2..237]
GPH_SALTI - Phosphoglycolate phosphatase OS=Salmonella typhi GN=gph PE=3 SV=1 GPH_SALTI - Phosphoglycolate phosphatase OS=Salmonella typhi GN=gph PE=3 SV=1 gi\|16762805 - gi\|16762805\|ref\|NP_458422.1\| phosphoglycolate phosphatase [Salmonella enterica subsp. enterica serov...	1.0E-35	[3..229]	[4..239]
gi\|126520826, gi... - gi\|153821629\|ref\|ZP_01974296.1\| haloacid dehalogenase/epoxide hydrolase family protein [Vibrio chole... gi\|153829003, gi... - gi\|153829003\|ref\|ZP_01981670.1\| haloacid dehalogenase/epoxide hydrolase family protein [Vibrio chole... gi\|227811728, gi... - gi\|227811728\|ref\|YP_002811738.1\| CbbY family protein [Vibrio cholerae M66-2], gi\|227010870\|gb\|ACP070... gi\|227119283, gi... - gi\|227119283\|ref\|YP_002821178.1\| CbbY family protein [Vibrio cholerae O395], gi\|227014733\|gb\|ACP1094... gi\|121726959, gi... - gi\|121726959\|ref\|ZP_01680155.1\| haloacid dehalogenase/epoxide hydrolase family protein [Vibrio chole... gi\|121586870, gi... - gi\|121586870\|ref\|ZP_01676651.1\| haloacid dehalogenase/epoxide hydrolase family protein [Vibrio chole... gi\|153221840, gi... - gi\|153221840\|ref\|ZP_01952705.1\| haloacid dehalogenase/epoxide hydrolase family protein [Vibrio chole... gi\|9657489, gi\|1... - gi\|9657489\|gb\|AAF96016.1\| CbbY family protein [Vibrio cholerae O1 biovar eltor str. N16961], gi\|1560... gi\|124116239, gi... - gi\|153212861\|ref\|ZP_01948478.1\| haloacid dehalogenase/epoxide hydrolase family protein [Vibrio chole... gi\|11354451 - pir\|\|A82498 CbbY family protein VCA0102 [imported] - Vibrio cholerae (strain N16961 serogroup O1) gi\|126511761, gi... - gi\|153817719\|ref\|ZP_01970386.1\| haloacid dehalogenase/epoxide hydrolase family protein [Vibrio chole... gi\|254850367, gi... - gi\|254850367\|ref\|ZP_05239717.1\| haloacid dehalogenase/epoxide hydrolase family protein [Vibrio chole...	1.0E-35	[1..233]	[1..219]

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Predicted Domain #1

Region A:
Residues: [1-20]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPQFSVDLCL FDLDGTIVST

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [79-246]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DNYLDTVSLI PGAENLLLSL DVDTETQKKL PERKWAIVTS GSPYLAFSWF ETILKNVGKP  60
   61 KVFITGFDVK NGKPDPEGYS RARDLLRQDL QLTGKQDLKY VVFEDAPVGI KAGKAMGAIT 120
  121 VGITSSYDKS VLFDAGADYV VCDLTQVSVV KNNENGIVIQ VNNPLTRD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	27.69897
Match:	1jud__
Description:	L-2-Haloacid dehalogenase, HAD
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [21-78]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTAAESAWKK LCRQHGVDPV ELFKHSHGAR SQEMMKKFFP KLDNTDNKGV LALEKDMA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	27.69897
Match:	1jud__
Description:	L-2-Haloacid dehalogenase, HAD
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits