YRC Public Data Repository - Protein Structure Prediction

Protein:	NEM1
Organism:	Saccharomyces cerevisiae
Length:	446 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NEM1.

Description	E-value	Query Range	Subject Range
NEM1 - Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme; regulates nuclear growth by contro... NEM1_YEAST - Nuclear envelope morphology protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NE...	0.0	[1..446]	[1..446]
SPBC3B8.10c - NLI interacting factor family NEM1_SCHPO - Nuclear envelope morphology protein 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=nem1...	3.0E-69	[92..440]	[120..476]
gi\|168279031 - gi\|168279031\|dbj\|BAG11395.1\| carboxy-terminal domain RNA polymerase II polypeptide A small phosphata... gi\|109097527 - gi\|109097527\|ref\|XP_001116527.1\| PREDICTED: nuclear LIM interactor-interacting factor 2 isoform 2 [M... gi\|67967557 - gi\|67967557\|dbj\|BAE00261.1\| unnamed protein product [Macaca fascicularis] CTDSP2 - CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 gi\|114644094 - gi\|114644094\|ref\|XP_001167131.1\| PREDICTED: nuclear LIM interactor-interacting factor 2 [Pan troglod...	2.0E-68	[174..442]	[25..273]
CTDSL_CHICK - CTD small phosphatase-like protein OS=Gallus gallus GN=NFI1 PE=2 SV=2 gi\|542165764\|ref... - PREDICTED: CTD small phosphatase-like protein isoform X2 [Zonotrichia albicollis] gi\|224044589 - gi\|224044589\|ref\|XP_002196491.1\| PREDICTED: CTD (carboxy-terminal domain, RNA polymerase II, polypep...	1.0E-65	[160..436]	[15..271]

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Predicted Domain #1

Region A:
Residues: [1-178]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNALKYFSNH LITTKKQKKI NVEVTKNQDL LGPSKEVSNK YTSHSENDCV SEVDQQYDHS  60
   61 SSHLKESDQN QERKNSVPKK PKALRSILIE KIASILWALL LFLPYYLIIK PLMSLWFVFT 120
  121 FPLSVIERRV KHTDKRNRGS NASENELPVS SSNINDSSEK TNPKNCNLNT IPEAVEDD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [179-446]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNASDEIILQ RDNVKGSLLR AQSVKSRPRS YSKSELSLSN HSSSNTVFGT KRMGRFLFPK  60
   61 KLIPKSVLNT QKKKKLVIDL DETLIHSASR STTHSNSSQG HLVEVKFGLS GIRTLYFIHK 120
  121 RPYCDLFLTK VSKWYDLIIF TASMKEYADP VIDWLESSFP SSFSKRYYRS DCVLRDGVGY 180
  181 IKDLSIVKDS EENGKGSSSS LDDVIIIDNS PVSYAMNVDN AIQVEGWISD PTDTDLLNLL 240
  241 PFLEAMRYST DVRNILALKH GEKAFNIN

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	100.180456
Match:	PF03031
Description:	NLI interacting factor-like phosphatase

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [228-446]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKRMGRFLFP KKLIPKSVLN TQKKKKLVID LDETLIHSAS RSTTHSNSSQ GHLVEVKFGL  60
   61 SGIRTLYFIH KRPYCDLFLT KVSKWYDLII FTASMKEYAD PVIDWLESSF PSSFSKRYYR 120
  121 SDCVLRDGVG YIKDLSIVKD SEENGKGSSS SLDDVIIIDN SPVSYAMNVD NAIQVEGWIS 180
  181 DPTDTDLLNL LPFLEAMRYS TDVRNILALK HGEKAFNIN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	59.39794
Match:	2q5eA
Description:	No description for 2q5eA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits