YRC Public Data Repository - Protein Structure Prediction

Protein:	YHL018W
Organism:	Saccharomyces cerevisiae
Length:	120 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YHL018W.

Description	E-value	Query Range	Subject Range
gi\|190405764 - gi\|190405764\|gb\|EDV09031.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a] gi\|151944182 - gi\|151944182\|gb\|EDN62474.1\| conserved protein [Saccharomyces cerevisiae YJM789] PHS_YEAST - Putative pterin-4-alpha-carbinolamine dehydratase OS=Saccharomyces cerevisiae (strain ATCC 204508 / ... YHL018W - Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mi...	1.0E-32	[1..120]	[1..120]
CE18240 - WBGene00020397 locus:pcbd-1 status:Partially_confirmed	8.0E-31	[7..116]	[78..177]
PHS_MOUSE - Pterin-4-alpha-carbinolamine dehydratase OS=Mus musculus GN=Pcbd1 PE=1 SV=2	1.0E-30	[8..119]	[3..104]
gi\|114631016 - gi\|114631016\|ref\|XP_001171466.1\| PREDICTED: similar to PCBD1 protein [Pan troglodytes] PCBD1 - pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha gi\|208967210 - gi\|208967210\|dbj\|BAG73619.1\| pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepat... gi\|194042768 - gi\|194042768\|ref\|XP_001928236.1\| PREDICTED: similar to pterin-4 alpha-carbinolamine dehydratase/dime... gi\|109089412 - gi\|109089412\|ref\|XP_001107537.1\| PREDICTED: similar to Pterin-4-alpha-carbinolamine dehydratase (PHS... ENSCJAT00000028755 - null PHS_RAT - Pterin-4-alpha-carbinolamine dehydratase OS=Rattus norvegicus GN=Pcbd1 PE=1 SV=2	2.0E-30	[8..119]	[3..104]
PHS_XENLA - Pterin-4-alpha-carbinolamine dehydratase OS=Xenopus laevis GN=pcbd PE=3 SV=3	3.0E-30	[8..119]	[3..104]
PHS_CHICK - Pterin-4-alpha-carbinolamine dehydratase OS=Gallus gallus GN=PCBD1 PE=2 SV=3	3.0E-30	[8..119]	[3..104]
gi\|1943051, gi\|1... - gi\|1943051\|pdb\|1DCP\|G Chain G, Dcoh, A Bifunctional Protein-Binding Transcriptional Coactivator, Com...	4.0E-30	[8..118]	[3..103]

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Predicted Domain #1

Region A:
Residues: [1-120]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHNKIVRIAS SALTGGKLLE KLKPLTRWEV QWDPNKTKCL GITREVTFKD YETTWAFLTR  60
   61 VSMRSHLWGH HPLIHTSYTW VKLELHTHDI DPKDGAHSQL SDIDVRMAKR IDSYIDEMTT 120
  121

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	68.211549
Match:	1dchA_
Description:	Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.633249790434806	bayes_pls_golite062009
binding	0.109738634058146	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: