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View Structure Prediction Details

Protein: LAG1
Organism: Saccharomyces cerevisiae
Length: 411 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LAG1.

Description E-value Query
Range
Subject
Range
LAG1_YEAST - Sphingosine N-acyltransferase LAG1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LAG1 ...
LAG1 - Ceramide synthase component, involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydro...
0.0 [1..411] [1..411]
mug83 - sphingosine N-acyltransferase Lac1
LAC1_SCHPO - Sphingosine N-acyltransferase lac1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=lac1 PE...
0.0 [15..384] [3..357]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
5.0E-90 [40..384] [1..330]
gi|148227942, gi... - gi|83405982|gb|AAI10704.1| LOC398230 protein [Xenopus laevis], gi|148227942|ref|NP_001082108.1| Tram...
5.0E-86 [62..408] [5..339]
TRAM1_MOUSE - Translocating chain-associated membrane protein 1 OS=Mus musculus GN=Tram1 PE=1 SV=3
2.0E-79 [56..385] [2..322]
gi|13936277 - gi|13936277|gb|AAK40297.1| Tram1 [Danio rerio]
2.0E-79 [57..385] [3..322]
TRAM1_CANLF - Translocating chain-associated membrane protein 1 OS=Canis lupus familiaris GN=TRAM1 PE=1 SV=2
7.0E-79 [56..385] [2..322]
gi|123984537, gi... - gi|60655235|gb|AAX32181.1| translocation associated membrane protein 1 [synthetic construct], gi|123...
TRAM1 - translocation associated membrane protein 1
8.0E-78 [56..385] [2..322]

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Predicted Domain #1
Region A:
Residues: [1-164]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSATDKSID RLVVNAKTRR RNSSVGKIDL GDTVPGFAAM PESAASKNEA KKRMKALTGD  60
   61 SKKDSDLLWK VWFSYREMNY RHSWLTPFFI LVCVYSAYFL SGNRTESNPL HMFVAISYQV 120
  121 DGTDSYAKGI KDLSFVFFYM IFFTFLREFL MDVVIRPFTV YLNV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [165-411]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSEHRQKRML EQMYAIFYCG VSGPFGLYIM YHSDLWLFKT KPMYRTYPVI TNPFLFKIFY  60
   61 LGQAAFWAQQ ACVLVLQLEK PRKDYKELVF HHIVTLLLIW SSYVFHFTKM GLAIYITMDV 120
  121 SDFFLSLSKT LNYLNSVFTP FVFGLFVFFW IYLRHVVNIR ILWSVLTEFR HEGNYVLNFA 180
  181 TQQYKCWISL PIVFVLIAAL QLVNLYWLFL ILRILYRLIW QGIQKDERSD SDSDESAENE 240
  241 ESKEKCE

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 85.207608
Match: PF03798
Description: Longevity-assurance protein (LAG1)

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [198-304]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLWLFKTKPM YRTYPVITNP FLFKIFYLGQ AAFWAQQACV LVLQLEKPRK DYKELVFHHI  60
   61 VTLLLIWSSY VFHFTKMGLA IYITMDVSDF FLSLSKTLNY LNSVFTP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [305-411]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FVFGLFVFFW IYLRHVVNIR ILWSVLTEFR HEGNYVLNFA TQQYKCWISL PIVFVLIAAL  60
   61 QLVNLYWLFL ILRILYRLIW QGIQKDERSD SDSDESAENE ESKEKCE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle