YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: COS6
Organism: Saccharomyces cerevisiae
Length: 381 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COS6.

Description E-value Query
Range
Subject
Range
COS1 - Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-enc...
COS1_YEAST - Protein COS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=COS1 PE=1 SV=1
609.0 [0..1] [381..1]

Back

Predicted Domain #1
Region A:
Residues: [1-61]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKENELKNEK SVDVLSVKQL ESQKTVLPQD LFRSSFTWFC YEIYKSLVFR IWMLLWLPLS  60
   61 V

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.639 N/A N/A a.60.1 SAM/Pointed domain
View Download 0.609 N/A N/A a.144.2 Ribosomal protein L20
View Download 0.562 N/A N/A a.60.8 HRDC-like
View Download 0.528 N/A N/A a.144.2 Ribosomal protein L20
View Download 0.437 N/A N/A a.118.1 ARM repeat
View Download 0.434 N/A N/A a.60.1 SAM/Pointed domain
View Download 0.434 N/A N/A a.60.1 SAM/Pointed domain
View Download 0.418 N/A N/A a.60.1 SAM/Pointed domain
View Download 0.418 N/A N/A a.60.1 SAM/Pointed domain
View Download 0.395 N/A N/A a.4.11 RNA polymerase subunit RPB10

Predicted Domain #2
Region A:
Residues: [62-169]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WWKLSNNWIY PLMVSLLVLF WGPVFVLVIF RLSRKRSLSK QLTQFCKEIT KNTPSSDPHD  60
   61 WEVVAANLNS YFYENKAWNT KYFFFSAMSC QEAFRTTLLE PFSLKKDE

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 48.251812
Match: PF00674
Description: DUP family

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.879 N/A N/A a.249.1 Description not found.
View Download 0.827 N/A N/A a.186.1 Description not found.
View Download 0.803 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.784 N/A N/A f.39.1 Description not found.
View Download 0.783 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.768 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.725 N/A N/A a.24.17 Group V grass pollen allergen
View Download 0.701 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.690 N/A N/A a.24.17 Group V grass pollen allergen

Predicted Domain #3
Region A:
Residues: [170-241]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAKVKSFKDS VPYIEEALEV YFTEVEKQWK LFNSEKSWSP VGLEDAKLPK EAYRFKLTWV  60
   61 LKRIFNRRCL PL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.615 d.58.57 Description not found.
View Download 0.615 a.159.5 Description not found.
View Download 0.585 d.58.17 Metal-binding domain
View Download 0.565 a.3.1 Cytochrome c
View Download 0.539 d.74.5 Hypothetical protein Yml108w
View Download 0.534 d.58.17 Metal-binding domain
View Download 0.534 d.58.17 Metal-binding domain
View Download 0.501 d.57.1 DNA damage-inducible protein DinI
View Download 0.455 a.60.4 DNA repair protein Rad51, N-terminal domain

Predicted Domain #4
Region A:
Residues: [242-381]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FLFYLHNVFI SRNDGTIARP LFLVVLFFIM TRDFRNMRMI VLSVKMEHKM QFLSTIINEQ  60
   61 ESGANGWDEI AKKMNRYLFE KKVWKNEEFF FDGIDCEWFF SHFFYRVLSA KKSMRALSLN 120
  121 VELWPYIKEA QLSCSEESLA 

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 58.744727
Match: PF00674
Description: DUP family

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.603 N/A N/A c.23.14 Nucleoside 2-deoxyribosyltransferase
View Download 0.562 N/A N/A a.118.1 ARM repeat
View Download 0.555 N/A N/A a.186.1 Description not found.
View Download 0.468 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.468 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.444 N/A N/A a.29.13 Description not found.
View Download 0.365 N/A N/A d.108.1 Acyl-CoA N-acyltransferases (Nat)
View Download 0.353 N/A N/A a.1.1 Globin-like
View Download 0.351 N/A N/A a.1.1 Globin-like
View Download 0.324 N/A N/A a.24.17 Group V grass pollen allergen


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle