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View Structure Prediction Details

Protein: ZUO1
Organism: Saccharomyces cerevisiae
Length: 433 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ZUO1.

Description E-value Query
Range
Subject
Range
ZUO1_YEAST - Zuotin OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ZUO1 PE=1 SV=1
ZUO1 - Cytosolic ribosome-associated chaperone that acts, together with Ssz1p and the Ssb proteins, as a ch...
5.0E-84 [1..433] [1..433]
gi|5577977 - gi|5577977|gb|AAD45407.1|AF118853_1 gliosarcoma-related antigen MIDA1 [Rattus norvegicus]
3.0E-78 [1..413] [1..412]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-73 [2..429] [7..440]
ZRF1_MOUSE - (P54103) Zuotin-related factor 1
2.0E-73 [1..413] [1..412]
gi|220946754 - gi|220946754|gb|ACL85920.1| CG10565-PA [synthetic construct]
FBpp0293954, CG1... - This gene is referred to in FlyBase by the symbol Dmel\CG10565 (CG10565, FBgn0037051). It is a prote...
4.0E-70 [25..406] [19..388]
gi|12322899, gi|... - gi|15229761|ref|NP_187752.1| DNAJ heat shock N-terminal domain-containing protein / cell division pr...
4.0E-65 [15..413] [45..439]
gi|1770454 - gi|1770454|emb|CAA66913.1| M-phase phosphoprotein 11 [Homo sapiens]
9.0E-63 [1..363] [15..375]

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Predicted Domain #1
Region A:
Residues: [1-82]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSLPTLTSD ITVEVNSSAT KTPFVRRPVE PVGKFFLQHA QRTLRNHTWS EFERIEAEKN  60
   61 VKTVDESNVD PDELLFDTEL AD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.540 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.626 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.533 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.524 a.90.1 Transcription factor STAT-4 N-domain
View Download 0.626 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.540 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.533 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.524 a.90.1 Transcription factor STAT-4 N-domain
View Download 0.514 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.514 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.433 a.1.1 Globin-like
View Download 0.430 a.7.6 Ribosomal protein S20
View Download 0.418 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.399 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.370 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.361 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.352 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.341 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.340 a.118.1 ARM repeat
View Download 0.335 a.39.1 EF-hand
View Download 0.325 a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.319 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.315 a.74.1 Cyclin-like
View Download 0.303 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.299 a.65.1 Annexin
View Download 0.291 c.78.2 Aspartate/glutamate racemase
View Download 0.286 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.281 a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.279 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.278 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.275 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.273 a.16.1 S15/NS1 RNA-binding domain
View Download 0.266 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.264 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.261 a.2.7 tRNA-binding arm
View Download 0.260 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.259 a.118.1 ARM repeat
View Download 0.252 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.251 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.250 a.118.1 ARM repeat
View Download 0.249 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.246 a.16.1 S15/NS1 RNA-binding domain
View Download 0.245 f.17.1 F1F0 ATP synthase subunit C
View Download 0.229 a.118.1 ARM repeat
View Download 0.218 a.159.2 FF domain
View Download 0.217 a.60.13 Putative methyltransferase TM0872, insert domain
View Download 0.215 a.118.1 ARM repeat
View Download 0.213 a.39.1 EF-hand
View Download 0.212 a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.206 a.74.1 Cyclin-like
View Download 0.204 a.74.1 Cyclin-like
View Download 0.203 a.16.1 S15/NS1 RNA-binding domain
View Download 0.202 d.95.2 Homing endonucleases

Predicted Domain #2
Region A:
Residues: [83-212]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDLLTHDARD WKTADLYAAM GLSKLRFRAT ESQIIKAHRK QVVKYHPDKQ SAAGGSLDQD  60
   61 GFFKIIQKAF ETLTDSNKRA QYDSCDFVAD VPPPKKGTDY DFYEAWGPVF EAEARFSKKT 120
  121 PIPSLGNKDS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 69.39794
Match: 1xbl__
Description: DnaJ chaperone, N-terminal (J) domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [213-433]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKKEVEQFYA FWHRFDSWRT FEFLDEDVPD DSSNRDHKRY IERKNKAARD KKKTADNARL  60
   61 VKLVERAVSE DPRIKMFKEE EKKEKERRKW EREAGARAEA EAKAKAEAEA KAKAESEAKA 120
  121 NASAKADKKK AKEAAKAAKK KNKRAIRNSA KEADYFGDAD KATTIDEQVG LIVDSLNDEE 180
  181 LVSTADKIKA NAAGAKEVLK ESAKTIVDSG KLPSSLLSYF V

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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