YRC Public Data Repository - Protein Structure Prediction

Protein:	YTA7
Organism:	Saccharomyces cerevisiae
Length:	1379 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YTA7.

Description	E-value	Query Range	Subject Range
gi\|1272680 - gi\|1272680\|emb\|CAA56963.1\| YTA7 [Saccharomyces cerevisiae]	1276.0	[0..1]	[1379..1]
YEJJ_SCHPO - Uncharacterized AAA domain-containing protein C31G5.19 OS=Schizosaccharomyces pombe (strain 972 / AT... SPAC31G5.19 - ATPase with bromodomain protein	814.0	[0..121]	[1379..2]
gi\|119524342, gi... - gi\|119719222\|ref\|YP_919717.1\| AAA family ATPase, CDC48 subfamily protein [Thermofilum pendens Hrk 5]...	761.0	[0..300]	[1011..76]
gi\|18159541, gi\|... - gi\|18312110\|ref\|NP_558777.1\| AAA family ATPase, CDC48 subfamily protein [Pyrobaculum aerophilum str....	743.0	[0..258]	[1005..5]
Y1297_ARCFU - Cell division cycle protein 48 homolog AF_1297 OS=Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 ... Y1297_ARCFU, YC9... - (O28972) Cell division cycle protein 48 homolog AF1297, Cell division cycle protein 48 homolog AF_12...	742.0	[0..274]	[999..25]
gi\|73971214 - gi\|73971214\|ref\|XP_866075.1\| PREDICTED: similar to Transitional endoplasmic reticulum ATPase (TER AT...	741.0	[0..219]	[987..16]
gi\|5106179, gi\|1... - gi\|5106179\|dbj\|BAA81490.1\| 699aa long hypothetical transitional endoplasmic reticulum ATPase [Aeropy... gi\|7435761 - pir\|\|B72479 probable transitional endoplasmic reticulum ATPase APE2474 - Aeropyrum pernix (strain K1...	738.0	[0..282]	[1006..6]

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Predicted Domain #1

Region A:
Residues: [1-154]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARNLRNRRG SDVEDASNAK VGYETQIKDE NGIIHTTTRS LRKINYAEIE KVFDFLEDDQ  60
   61 VMDKDETPVD VTSDEHHNNN QKGDDEDDDV DLVSPHENAR TNEELTNERN LRKRKAHDPE 120
  121 EDDESFHEED VDDDEEEEEA DEFEDEYLDE DSKD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [155-302]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNRRRRAADR KFVVPDPDDD EEYDEDDEEG DRISHSASSK RLKRANSRRT RSSRHPETPP  60
   61 PVRRALRSRT RHSRTSNEEN DDENDNSRNE ALTLADEIRE LQEDSPIREK RFLRERTKPV 120
  121 NYKLPPPLTA SNAEEFIDKN NNALSFHN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	678.228787
Match:	1e32A
Description:	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [303-409]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSPARRGRGG WNASQNSGPT RRLFPTGGPF GGNDVTTIFG KNTNFYNQVP SAFSDNNNNK  60
   61 LILDSDSSDD EILPLGVTPK TKKENTQKKK KKKPEIADLD PLGVDMN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	678.228787
Match:	1e32A
Description:	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [410-585]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VNFDDIGGLD NYIDQLKEMV ALPLLYPELY QNFNITPPRG VLFHGPPGTG KTLMARALAA  60
   61 SCSSDERKIT FFMRKGADIL SKWVGEAERQ LRLLFEEAKK HQPSIIFFDE IDGLAPVRSS 120
  121 KQEQIHASIV STLLALMDGM DNRGQVIVIG ATNRPDAVDP ALRRPGRFDR EFYFPL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	678.228787
Match:	1e32A
Description:	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #5

Region A:
Residues: [586-730]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDVKARFKIL QIQTRKWSSP LSTNFIDKLA FLTKGYGGAD LRSLCTEAAL ISIQRSFPQI  60
   61 YRSNDKLLVD PSKIKVKVSD FMLALKKIVP SSARSTGSSP QPLPELIKPL LADQLNNLKN 120
  121 KLDYMLNIKD TTFQRNTSLL QNFID

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	678.228787
Match:	1e32A
Description:	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #6

Region A:
Residues: [731-922]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YEEYSGEEEE HDKYGGNEDT SSFRSYEFFE SMAESQICKP RLLINGPKGN GQQYVGAAIL  60
   61 NYLEEFNVQN LDLASLVSES SRTIEAAVVQ SFMEAKKRQP SVVFIPNLDI WINTIPENVI 120
  121 LVLSGLFRSL QSNEKILLLC LAENLDISEV KNGILSDFAF DKNIFQLHKP SKENITRYFS 180
  181 NLIELLKTKP SD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	5.0
Match:	1iqpA
Description:	Replication factor C
Matching Structure (courtesy of the PDB):

Predicted Domain #7

Region A:
Residues: [923-1138]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPMKKRRVKP LPELQKVTSN AAPTNFDENG EPLSEKVVLR RKLKSFQHQD MRLKNVLKIK  60
   61 LSGLMDLFKN RYKRFRKPPI DDAFLVHLFE PETSNDPNWQ PAYIKDENMI LEVSTGRKFF 120
  121 NMDLDIVEER LWNGYYSEPK QFLKDIELIY RDANTIGDRE RVIKASEMFA NAQMGIEEIS 180
  181 TPDFIQECKA TRQRDLERQE LFLEDEEKRA AMELEA

[Run NCBI BLAST on this sequence.]

Detection Method:	ab initio
Confidence:	14.04
Match:
Description:	No description for 1eqfA was found.

Predicted Domain #8

Region A:
Residues: [1139-1285]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KEQSQENILQ EPDLKDNKAN EFGVAAGNQL QAQLQTTINT ASIVNNSEVP QPIDTNLYKK  60
   61 EIPAAIPSAV DKEKAVIPED SGANEEYTTE LIQATCTSEI TTDDDERARK EPKENEDSLQ 120
  121 TQVTEENFSK IDANTNNINH VKEIQSV

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9

Region A:
Residues: [1286-1379]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKPNSLHETV EKRERSPIPK EVVEPEQGKK SDKELILTPE QIKKVSACLI EHCQNFTVSQ  60
   61 LEDVHSSVAK IIWKSKSAWD KTGTVDEIIK FLSE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.897	a.24.17	Group V grass pollen allergen

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits