YRC Public Data Repository - Protein Structure Prediction

Protein:	YGR266W
Organism:	Saccharomyces cerevisiae
Length:	701 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YGR266W.

Description	E-value	Query Range	Subject Range
gi\|207344894 - gi\|207344894\|gb\|EDZ71883.1\| YGR266Wp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|190406731 - gi\|190406731\|gb\|EDV09998.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a] YG5L_YEAST - Uncharacterized protein YGR266W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YGR266W ... YGR266W - Protein of unknown function, predicted to contain a single transmembrane domain; localized to both t...	0.0	[1..701]	[1..701]

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Predicted Domain #1

Region A:
Residues: [1-701]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHATNWFDDW NPEALYRDDV TGCDDCSETS PIPKSGIICG PILRLINMDF KEKTYEGSIM  60
   61 VVVRGEENFP KITYQLGPSL PSEDEDIEVN EAFFEGKLFH KDILKDDNIW FYRYEIKLPM 120
  121 SNYEQMVKYA VDGTMEPHYR FFVPSFTQNS NVISYSCNGF SLSVDTSKFK GSLWYDVLKK 180
  181 HRYVHYHAIL GGGDQIYSDN IKLHAPNLKA WLETKDPIKK YNTQTTEETK EQIRQFYLEH 240
  241 YLNWYGYGHW YGSTPKSKTT QKCFVKSLAC IPAINVWDDH DIIDGYGSYN DSFMKTENFL 300
  301 TVGRMAYRYY MLFQQHVSAS KQDGDEYAYL KSKQWILGNE KGSSYIGERS HSIFSWLGPK 360
  361 MAMLGLDCRT ERKLHEIFSE RSYSLIWERV EREIKNLKGG HLLLMLGIPI AYPRLVWLEW 420
  421 LFTSKLLAPI KYLSKKGIFA SGFVNEFNGD VELLDDLNDH WCARHHKKER NYLIMKLQDI 480
  481 GAKYGVRITI LSGDVHLASV GRFRAKIHRH HLIMSEEKEK ENTRIIEEPT KDVRLIFNII 540
  541 ASAIVNTPPP DAMATLLQKR CRLHHFDLET DEDAVPIFAK EVDGVHKRKE SCFMNKRNWS 600
  601 DIIPIENLLN NPQLSKELGV KVGDIVIPGI ITEQQKLQKL ENDDQINSYP VTSGGLFTTI 660
  661 HVERDANQTN SQTVSYCLPI PELTVTCERL SHKGIKHLNI T

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
hydrolase activity	0.701730308631231	bayes_pls_golite062009
catalytic activity	0.533948408743745	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.271364597009264	bayes_pls_golite062009
phosphoric ester hydrolase activity	0.218300387829921	bayes_pls_golite062009
phosphatase activity	0.0715182705357755	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [604-701]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PIENLLNNPQ LSKELGVKVG DIVIPGIITE QQKLQKLEND DQINSYPVTS GGLFTTIHVE  60
   61 RDANQTNSQT VSYCLPIPEL TVTCERLSHK GIKHLNIT