YRC Public Data Repository - Protein Structure Prediction

Protein:	GPI1
Organism:	Saccharomyces cerevisiae
Length:	609 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GPI1.

Description	E-value	Query Range	Subject Range
GPI1 - Membrane protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI),... gi\|190406774 - gi\|190406774\|gb\|EDV10041.1\| phosphatidylinositol N-acetylglucosaminyltransferase GPI1 subunit [Sacch... gi\|151943493 - gi\|151943493\|gb\|EDN61804.1\| glycosylphosphatidylinositol anchoring biosynthesis [Saccharomyces cerev... GPI1_YEAST - Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI1 OS=Saccharomyces cerevisiae (strai...	0.0	[1..609]	[1..609]
gi\|5912462 - gi\|5912462\|emb\|CAB56148.1\| OTTHUMP00000045525 [Homo sapiens]	0.0	[74..576]	[89..572]
gi\|2623160 - gi\|2623160\|gb\|AAC79574.1\| N-acetylglucosaminyl transferase component Gpi1 [Mus musculus] gi\|56090291, gi\|... - gi\|56090291\|ref\|NP_001007608.1\| phosphatidylinositol glycan anchor biosynthesis, class Q [Rattus nor...	0.0	[75..576]	[90..570]
gpi1 - pig-Q GPI1_SCHPO - N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein gpi1 OS=Schizosaccharomyces pombe (st...	0.0	[75..601]	[125..640]
gi\|1763537 - gi\|1763537\|gb\|AAC49650.1\| Gpi1+ [Schizosaccharomyces pombe]	0.0	[87..601]	[1..504]
gi\|10303375 - gi\|10303375\|emb\|CAC10160.1\| N-acetylglucosamine transferase [Plasmodium falciparum]	7.0E-90	[118..530]	[193..607]
gi\|10303240 - gi\|10303240\|emb\|CAC10057.1\| GPI1 protein [Drosophila virilis]	6.0E-70	[261..514]	[188..439]

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Predicted Domain #1

Region A:
Residues: [1-258]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNYIFWPYE SLFENSAAQG PQVALAISFE KTHFVVLGVC EPQYLEEVSI RPPYSVVATK  60
   61 NNGAEGWNYK VADPCNVHFR IPKLKFMQFY SSDPISLIIP EKEVGLHSSV GETLNYSKLE 120
  121 QHPRYKRDNK KLSETLNIIN LFPAYCKALN ELYPFIQTSQ ENLRGTMLNS VAAWCSSTCI 180
  181 YKMVAKIGFY LTFVICSIAS LVSSLLNYSH FQLVNYSAFV QQIDLRCQQI CYFPVQYERI 240
  241 NKKDNIQNVG SMVEKDNS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [259-609]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSQFSHSYMP SKFYPDYILL YNTIWLIIND ISFGLILGAI LIENRDFLVS ASHRVLKFFL  60
   61 YDSLKTITET LANNPLGIKL NAELANFLSE LFLWVIEFSY TTFIKRLIDP KTLSSLLTLT 120
  121 IYMMFLVGFS FAVSLAIDFF AILSFPIYVF YRISSKLYHC QLNIMASLFN LFCGKKRNVL 180
  181 RNRIDHNYFQ LDQLLLGTLL FIILVFLTPT VMAFYMSYTV LRMLTITIEI FSEAVIALIN 240
  241 HFPLFALLLR LKDPKRLPGG ISIELKTTVS NKHTTLELQN NPIKFKSMFR PYNLLLSQMR 300
  301 TNYFSFATVR KIVRGESIMV NRNKLYYVLY SSLPSKPLSV KDLYKRLTIQ A

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits