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View Structure Prediction Details

Protein: CLC1
Organism: Saccharomyces cerevisiae
Length: 233 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CLC1.

Description E-value Query
Range
Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
5.0E-61 [34..227] [56..282]
gi|225494, gi|510 - gi|510|emb|CAA28542.1| unnamed protein product [Bos taurus], gi|225494|prf||1304303B clathrin LCa
6.0E-59 [34..227] [15..209]
CLTA - clathrin, light chain A
gi|208966052 - gi|208966052|dbj|BAG73040.1| clathrin, light chain [synthetic construct]
2.0E-57 [34..227] [18..244]
CLC1_YEAST - Clathrin light chain OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CLC1 PE=1 SV=1
CLC1 - Clathrin light chain, subunit of the major coat protein involved in intracellular protein transport ...
1.0E-56 [1..233] [1..233]
CLCA_RAT - Clathrin light chain A OS=Rattus norvegicus GN=Clta PE=1 SV=1
6.0E-56 [34..227] [18..244]
CLCA_MOUSE - Clathrin light chain A OS=Mus musculus GN=Clta PE=1 SV=1
7.0E-56 [34..227] [18..231]

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Predicted Domain #1
Region A:
Residues: [1-233]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEKFPPLED QNIDFTPNDK KDDDTDFLKR EAEILGDEFK TEQDDILETE ASPAKDDDEI  60
   61 RDFEEQFPDI NSANGAVSSD QNGSATVSSG NDNGEADDDF STFEGANQST ESVKEDRSEV 120
  121 VDQWKQRRAV EIHEKDLKDE ELKKELQDEA IKHIDDFYDS YNKKKEQQLE DAAKEAEAFL 180
  181 KKRDEFFGQD NTTWDRALQL INQDDADIIG GRDRSKLKEI LLRLKGNAKA PGA

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 145.657577
Match: PF01086
Description: Clathrin light chain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [96-233]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADDDFSTFEG ANQSTESVKE DRSEVVDQWK QRRAVEIHEK DLKDEELKKE LQDEAIKHID  60
   61 DFYDSYNKKK EQQLEDAAKE AEAFLKKRDE FFGQDNTTWD RALQLINQDD ADIIGGRDRS 120
  121 KLKEILLRLK GNAKAPGA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.522879
Match: 1xi4J
Description: Clathrin D6 Coat
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle