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View Structure Prediction Details

Protein: NUP57
Organism: Saccharomyces cerevisiae
Length: 541 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUP57.

Description E-value Query
Range
Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-83 [139..536] [34..423]
nup44 - nucleoporin Nup44
NUP44_SCHPO - Nucleoporin nup44 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=nup44 PE=2 SV=1
4.0E-81 [139..536] [3..392]
NUP57 - Nucleoporin, essential subunit of the nuclear pore complex (NPC), functions as the organizing center...
NUP57_YEAST - Nucleoporin NUP57 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NUP57 PE=1 SV=1
3.0E-77 [1..541] [1..541]
gi|19309407 - gi|19309407|emb|CAD27306.1| putative nucleoporin [Aspergillus fumigatus]
gi|70995682, gi|... - gi|70995682|ref|XP_752596.1| nucleoporin, putative [Aspergillus fumigatus Af293], gi|66850231|gb|EAL...
4.0E-71 [94..520] [4..414]
NUP54_RAT - Nuclear pore complex protein Nup54 OS=Rattus norvegicus GN=Nup54 PE=1 SV=1
2.0E-59 [325..535] [302..492]
NUP54_ARATH - Nuclear pore complex protein NUP54 OS=Arabidopsis thaliana GN=NUP54 PE=1 SV=1
6.0E-57 [151..534] [1..363]
gi|18032249 - gi|18032249|gb|AAL56659.1|AF231130_1 NUP196 nucleoporin [Homo sapiens]
4.0E-45 [2..328] [42..408]
gi|6010435 - gi|6010435|gb|AAF01135.1| erythrocyte membrane protein 3 [Plasmodium falciparum]
2.0E-42 [5..333] [1352..1680]

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Predicted Domain #1
Region A:
Residues: [1-287]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFGFSGSNNG FGNKPAGSTG FSFGQNNNNT NTQPSASGFG FGGSQPNSGT ATTGGFGANQ  60
   61 ATNTFGSNQQ SSTGGGLFGN KPALGSLGSS STTASGTTAT GTGLFGQQTA QPQQSTIGGG 120
  121 LFGNKPTTTT GGLFGNSAQN NSTTSGGLFG NKVGSTGSLM GGNSTQNTSN MNAGGLFGAK 180
  181 PQNTTATTGG LFGSKPQGST TNGGLFGSGT QNNNTLGGGG LFGQSQQPQT NTAPGLGNTV 240
  241 STQPSFAWSK PSTGSNLQQQ QQQQIQVPLQ QTQAIAQQQQ LSNYPQQ

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.2
Match: 1ldvA
Description: No description for 1ldvA was found.

Predicted Domain #2
Region A:
Residues: [288-427]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IQEQVLKCKE SWDPNTTKTK LRAFVYNKVN ETEAILYTKP GHVLQEEWDQ AMEKKPSPQT  60
   61 IPIQIYGFEG LNQRNQVQTE NVAQARIILN HILEKSTQLQ QKHELDTASR ILKAQSRNVE 120
  121 IEKRILKLGT QLATLKNRGL 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.221849
Match: 1avc__
Description: Annexin VI
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [428-541]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLGIAEEKMW SQFQTLLQRS EDPAGLGKTN ELWARLAILK ERAKNISSQL DSKLMVFNDD  60
   61 TKNQDSMSKG TGEESNDRIN KIVEILTNQQ RGITYLNEVL EKDAAIVKKY KNKT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.606 0.291 snRNA export from nucleus a.1.1 Globin-like
View Download 0.917 0.291 snRNA export from nucleus a.25.1 Ferritin-like
View Download 0.461 0.291 snRNA export from nucleus a.167.1 Porin chaperone SurA, peptide-binding domain
View Download 0.456 0.291 snRNA export from nucleus a.1.1 Globin-like
View Download 0.402 0.291 snRNA export from nucleus a.1.1 Globin-like
View Download 0.394 0.291 snRNA export from nucleus a.25.1 Ferritin-like
View Download 0.392 0.291 snRNA export from nucleus a.133.1 Phospholipase A2, PLA2
View Download 0.391 0.291 snRNA export from nucleus d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.359 0.291 snRNA export from nucleus a.24.3 Cytochromes
View Download 0.345 0.291 snRNA export from nucleus a.25.1 Ferritin-like
View Download 0.339 0.291 snRNA export from nucleus c.23.1 CheY-like
View Download 0.335 0.291 snRNA export from nucleus a.39.4 Hypothetical protein MTH865
View Download 0.332 0.291 snRNA export from nucleus a.29.4 RecG, N-terminal domain
View Download 0.327 0.291 snRNA export from nucleus a.60.11 Hypothetical protein YjbJ
View Download 0.324 0.291 snRNA export from nucleus a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.299 0.291 snRNA export from nucleus a.1.1 Globin-like
View Download 0.288 0.291 snRNA export from nucleus a.24.9 alpha-catenin/vinculin
View Download 0.282 0.291 snRNA export from nucleus c.47.1 Thioredoxin-like
View Download 0.281 0.291 snRNA export from nucleus a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.280 0.291 snRNA export from nucleus a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.277 0.291 snRNA export from nucleus a.74.1 Cyclin-like
View Download 0.276 0.291 snRNA export from nucleus a.74.1 Cyclin-like
View Download 0.274 0.291 snRNA export from nucleus a.74.1 Cyclin-like
View Download 0.274 0.291 snRNA export from nucleus a.130.1 Chorismate mutase II
View Download 0.273 0.291 snRNA export from nucleus a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.270 0.291 snRNA export from nucleus a.60.9 lambda integrase-like, N-terminal domain
View Download 0.268 0.291 snRNA export from nucleus a.142.1 PTS-regulatory domain, PRD
View Download 0.268 0.291 snRNA export from nucleus a.39.1 EF-hand
View Download 0.267 0.291 snRNA export from nucleus f.14.1 Voltage-gated potassium channels
View Download 0.266 0.291 snRNA export from nucleus f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.259 0.291 snRNA export from nucleus d.52.2 GMP synthetase C-terminal dimerisation domain
View Download 0.257 0.291 snRNA export from nucleus a.4.1 Homeodomain-like
View Download 0.255 0.291 snRNA export from nucleus a.25.1 Ferritin-like
View Download 0.253 0.291 snRNA export from nucleus f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.234 0.291 snRNA export from nucleus a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.230 0.291 snRNA export from nucleus a.61.1 Retroviral matrix proteins
View Download 0.230 0.291 snRNA export from nucleus c.54.1 IIA domain of mannose transporter, IIA-Man
View Download 0.223 0.291 snRNA export from nucleus e.37.1 Bifunctional dehydrogenase/ferrochelatase Met8p, dimerisation and C-terminal domains
View Download 0.219 0.291 snRNA export from nucleus a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.215 0.291 snRNA export from nucleus d.58.39 Glutamyl tRNA-reductase catalytic, N-terminal domain
View Download 0.214 0.291 snRNA export from nucleus a.26.1 4-helical cytokines
View Download 0.213 0.291 snRNA export from nucleus a.39.1 EF-hand
View Download 0.211 0.291 snRNA export from nucleus a.40.1 Calponin-homology domain, CH-domain
View Download 0.209 0.291 snRNA export from nucleus c.95.1 Thiolase-like
View Download 0.209 0.291 snRNA export from nucleus d.6.1 Prion-like
View Download 0.207 0.291 snRNA export from nucleus a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.207 0.291 snRNA export from nucleus a.24.17 Group V grass pollen allergen
View Download 0.203 0.291 snRNA export from nucleus a.39.1 EF-hand
View Download 0.203 0.291 snRNA export from nucleus d.19.1 MHC antigen-recognition domain
View Download 0.202 0.291 snRNA export from nucleus a.74.1 Cyclin-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle