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View Structure Prediction Details

Protein: DBF2
Organism: Saccharomyces cerevisiae
Length: 572 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DBF2.

Description E-value Query
Range
Subject
Range
DBF2_YEAST - Cell cycle protein kinase DBF2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DBF2 PE=1...
DBF2 - Ser/Thr kinase involved in transcription and stress response; functions as part of a network of gene...
0.0 [1..572] [1..572]
gi|7339534 - gi|7339534|emb|CAB82852.1| protein kinase MK6 [Mesembryanthemum crystallinum]
0.0 [62..553] [14..494]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [64..553] [2..491]
gi|125532353 - gi|125532353|gb|EAY78918.1| hypothetical protein OsI_34019 [Oryza sativa Indica Group]
gi|13129502, gi|... - gi|37535354|ref|NP_921979.1| putative protein kinase [Oryza sativa (japonica cultivar-group)], gi|31...
0.0 [64..553] [2..485]
gi|15219591 - gi|15219591|ref|NP_171888.1| protein kinase, putative [Arabidopsis thaliana]
0.0 [75..553] [38..506]

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Predicted Domain #1
Region A:
Residues: [1-95]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSKSEKNVD LLAGNMSNLS FDGHGTPGGT GLFPNQNITK RRTRPAGIND SPSPVKPSFF  60
   61 PYEDTSNMDI DEVSQPDMDV SNSPKKLPPK FYERA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [96-172]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSNKTQRVVS VCKMYFLEHY CDMFDYVISR RQRTKQVLEY LQQQSQLPNS DQIKLNEEWS  60
   61 SYLQREHQVL RKRRLKP

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [221-240]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HVLTERDILT TTRSEWLVKL 

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [256-505]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FVPGGDFRTL LINTRCLKSG HARFYISEMF CAVNALHDLG YTHRDLKPEN FLIDAKGHIK  60
   61 LTDFGLAAGT ISNERIESMK IRLEKIKDLE FPAFTEKSIE DRRKMYNQLR EKEINYANSM 120
  121 VGSPDYMALE VLEGKKYDFT VDYWSLGCML FESLVGYTPF SGSSTNETYD NLRRWKQTLR 180
  181 RPRQSDGRAA FSDRTWDLIT RLIADPINRL RSFEHVKRMS YFADINFSTL RSMIPPFTPQ 240
  241 LDSETDAGYF 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 513.0
Match: 1ctpE_
Description: cAMP-dependent PK, catalytic subunit
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [173-220]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KNRDFEMITQ VGQGGYGQVY LARKKDTKEV CALKILNKKL LFKLNETK

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [241-255]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LYAFQDLQSL YLAME

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [506-572]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDFTSEADMA KYADVFKRQD KLTAMVDDSA VSSKLVGFTF RHRNGKQGSS GILFNGLEHS  60
   61 DPFSTFY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 513.0
Match: 1ctpE_
Description: cAMP-dependent PK, catalytic subunit
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle