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View Structure Prediction Details

Protein: TIM21
Organism: Saccharomyces cerevisiae
Length: 239 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TIM21.

Description E-value Query
Range
Subject
Range
TIM21_YEAST - Mitochondrial import inner membrane translocase subunit TIM21 OS=Saccharomyces cerevisiae (strain AT...
TIM21 - Nonessential subunit of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); interac...
2.0E-98 [1..239] [1..239]
gi|12850553 - gi|12850553|dbj|BAB28768.1| unnamed protein product [Mus musculus]
2.0E-67 [10..216] [39..235]
gi|6841530, gi|7... - gi|7661810|ref|NP_054896.1| hypothetical protein LOC29090 [Homo sapiens], gi|6841530|gb|AAF29118.1|A...
1.0E-66 [10..216] [41..239]
TIM21_SCHPO - Mitochondrial import inner membrane translocase subunit tim21 OS=Schizosaccharomyces pombe (strain 9...
tim21 - mitochondrial inner membrane presequence translocase complex subunit Tim21
3.0E-48 [28..203] [9..188]
CE25907 - status:Partially_confirmed UniProt:Q9TXR7 protein_id:AAK29831.1
5.0E-41 [57..202] [63..198]

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Predicted Domain #1
Region A:
Residues: [1-239]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSLPRSLL RLGHRKPLFP RYNTFVNSSV ITHTSLLRTR LYSNGTGATS GKKDDKTRNK  60
   61 PKPLWPQVKS ASTFTFSGIL VIGAVGISAI VIYLILSELF SPSGDTQLFN RAVSMVEKNK 120
  121 DIRSLLQCDD GITGKERLKA YGELITNDKW TRNRPIVSTK KLDKEGRTHH YMRFHVESKK 180
  181 KIALVHLEAK ESKQNYQPDF INMYVDVPGE KRYYLIKPKL HPVSNSKGFL GIRWGPRKD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.459 N/A N/A a.23.5 Hemolysin expression modulating protein HHA
View Download 0.275 N/A N/A a.65.1 Annexin
View Download 0.257 N/A N/A a.7.7 BAG domain
View Download 0.219 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain

Predicted Domain #2
Region A:
Residues: [102-239]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSGDTQLFNR AVSMVEKNKD IRSLLQCDDG ITGKERLKAY GELITNDKWT RNRPIVSTKK  60
   61 LDKEGRTHHY MRFHVESKKK IALVHLEAKE SKQNYQPDFI NMYVDVPGEK RYYLIKPKLH 120
  121 PVSNSKGFLG IRWGPRKD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.0
Match: 2ciuA
Description: No description for 2ciuA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle