YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: YGR012W
Organism: Saccharomyces cerevisiae
Length: 393 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YGR012W.

Description E-value Query
Range		 Subject
Range
CBS_RAT - Cystathionine beta-synthase OS=Rattus norvegicus GN=Cbs PE=1 SV=3
 0.0 [43..390] [71..398]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 0.0 [43..390] [71..398]
CBS_MOUSE - Cystathionine beta-synthase OS=Mus musculus GN=Cbs PE=1 SV=3
 0.0 [43..390] [71..398]
gi|3850687 - gi|3850687|emb|CAA61252.1| cystathionine beta-synthase [Homo sapiens]
 5.0E-99 [7..389] [45..400]

Back

Predicted Domain #1
Region A:
Residues: [1-96] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSCSQNKTSV SLAWRECISI ASVLIGAYAS YKYYKLFKTR DIPRPKEGVE ELIGNTPLVK  60
   61 IRSLTKATGV NIYAKLELCN PAGSAKDRVA LNIIKT

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [196-393] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QFENEANWKV HYQTTGPEIA HQTKGNIDAF IAGCGTGGTI TGVAKFLKER AKIPCHVVLA  60
   61 DPQGSGFYNR VNYGVMYDYV EKEGTRRRHQ VDTIVEGIGL NRITHNFHMG EKFIDESIRV 120
  121 NDNQAIRMAK YLSVNDGLFV GSSTAINAVA AIQVAKTLPH GSNIVIIACD SGSRHLSKFW 180
  181 KEAKEIDHDV SLEEVINI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 518.39794
Match: 1jbqA_
Description: Cystathionine beta-synthase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cysteine synthase activity 5.18562032111987 bayes_pls_golite062009
catalytic activity 2.38994231321972 bayes_pls_golite062009
lyase activity 1.87743897464083 bayes_pls_golite062009
cystathionine beta-synthase activity 1.4517088142802 bayes_pls_golite062009
tryptophan synthase activity 1.04832999357666 bayes_pls_golite062009
carbon-oxygen lyase activity 0.923824749425553 bayes_pls_golite062009
threonine synthase activity 0.727838845253199 bayes_pls_golite062009
ammonia-lyase activity 0.476674617721478 bayes_pls_golite062009
L-threonine ammonia-lyase activity 0.37325071016009 bayes_pls_golite062009
carbon-nitrogen lyase activity 0.249761226675912 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [97-195] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEELGELVRG EPGWVFEGTS GSTGISIAVV CNALGYRAHI SLPDDTSLEK LALLESLGAT  60
   61 VNKVKPASIV DPNQYVNAAK KACNELKKSG NGIRAVFAD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 518.39794
Match: 1jbqA_
Description: Cystathionine beta-synthase
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle