YRC Public Data Repository - Protein Structure Prediction

Protein:	SDT1
Organism:	Saccharomyces cerevisiae
Length:	280 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SDT1.

Description	E-value	Query Range	Subject Range
SDT1 - Pyrimidine nucleotidase; overexpression suppresses the 6-AU sensitivity of transcription elongation ... SDT1_YEAST - Suppressor of disruption of TFIIS OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SDT1 P...	3.0E-55	[1..280]	[1..280]
YG55_PYRHO, Y165... - (O59346) Putative HAD-hydrolase PH1655 (EC 3.-.-.-), Uncharacterized HAD-hydrolase PH1655 OS=Pyrococ... G3PP_PYRHO - Glyceraldehyde 3-phosphate phosphatase OS=Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JC...	6.0E-38	[54..278]	[1..226]
G3PP_PYRAB - Glyceraldehyde 3-phosphate phosphatase OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=PYRAB05140 PE=3 ... YB10_PYRAB - Uncharacterized HAD-hydrolase PYRAB05140 OS=Pyrococcus abyssi GN=PYRAB05140 PE=3 SV=1	8.0E-38	[54..278]	[1..226]
Y1777_PYRFU, YH7... - (Q8U040) Putative HAD-hydrolase PF1777 (EC 3.-.-.-), Uncharacterized HAD-hydrolase PF1777 OS=Pyrococ... G3PP_PYRFU - Glyceraldehyde 3-phosphate phosphatase OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 84...	3.0E-36	[53..278]	[2..228]
GPH2_PSEAE - Phosphoglycolate phosphatase 2 OS=Pseudomonas aeruginosa GN=gph2 PE=3 SV=1 GPH2_PSEAE - Phosphoglycolate phosphatase 2 OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / ...	7.0E-36	[51..278]	[2..221]
GPH_HAEIN - Phosphoglycolate phosphatase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) G... GPH_HAEIN - Phosphoglycolate phosphatase OS=Haemophilus influenzae GN=gph PE=3 SV=1	4.0E-35	[55..276]	[5..224]
NANP - N-acetylneuraminic acid phosphatase gi\|190691161, gi... - gi\|190691161\|gb\|ACE87355.1\| N-acetylneuraminic acid phosphatase protein [synthetic construct], gi\|19...	2.0E-34	[54..279]	[5..240]
NANP_MOUSE - N-acylneuraminate-9-phosphatase OS=Mus musculus GN=Nanp PE=1 SV=1	5.0E-34	[54..279]	[5..240]
gi\|25499690 - pir\|\|F96977 probable phosphatase [imported] - Clostridium acetobutylicum gi\|15893920, gi\|... - gi\|15893920\|ref\|NP_347269.1\| phosphatase [Clostridium acetobutylicum ATCC 824], gi\|15023504\|gb\|AAK78...	1.0E-33	[54..272]	[1..210]

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Predicted Domain #1

Region A:
Residues: [1-69]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVEYTASDL ATYQNEVNEQ IAKNKAHLES LTHPGSKVTF PIDQDISATP QNPNLKVFFF  60
   61 DIDNCLYKS

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [133-280]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPLQDILKPD IPLRNMLLRL RQSGKIDKLW LFTNAYKNHA IRCLRLLGIA DLFDGLTYCD  60
   61 YSRTDTLVCK PHVKAFEKAM KESGLARYEN AYFIDDSGKN IETGIKLGMK TCIHLVENEV 120
  121 NEILGQTPEG AIVISDILEL PHVVSDLF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	27.0
Match:	1jud__
Description:	L-2-Haloacid dehalogenase, HAD
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [70-132]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STRIHDLMQQ SILRFFQTHL KLSPEDAHVL NNSYYKEYGL AIRGLVMFHK VNALEYNRLV  60
   61 DDS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	27.0
Match:	1jud__
Description:	L-2-Haloacid dehalogenase, HAD
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits