YRC Public Data Repository - Protein Structure Prediction

Protein:	AMS1
Organism:	Saccharomyces cerevisiae
Length:	1083 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AMS1.

Description	E-value	Query Range	Subject Range
gi\|171057, gi\|171058 - gi\|171058\|gb\|AAA34423.1\| alpha-D-mannosidase (EC 3.2.1.24), gi\|171057\|gb\|AAA34422.1\| alpha-mannosida...	1366.0	[0..1]	[1083..1]
gi\|49525218 - gi\|49525218\|emb\|CAG58831.1\| unnamed protein product [Candida glabrata] gi\|49525218, gi\|... - gi\|50286965\|ref\|XP_445912.1\| unnamed protein product [Candida glabrata], gi\|49525218\|emb\|CAG58831.1\|...	1105.0	[0..4]	[1083..8]
ams1 - alpha-mannosidase MAN1_SCHPO - Alpha-mannosidase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ams1 PE=3 SV=1	1096.0	[0..10]	[1081..11]
MA2C1_MOUSE - Alpha-mannosidase 2C1 OS=Mus musculus GN=Man2c1 PE=1 SV=1	1025.0	[0..67]	[1081..45]
gi\|56540863 - gi\|56540863\|gb\|AAH86989.1\| Mannosidase, alpha, class 2C, member 1 [Rattus norvegicus]	1024.0	[0..67]	[1081..45]
gi\|44986415, gi\|... - gi\|45201481\|ref\|NP_987051.1\| AGR385Cp [Ashbya gossypii ATCC 10895], gi\|44986415\|gb\|AAS54875.1\| AGR38... gi\|44986415 - gi\|44986415\|gb\|AAS54875.1\| AGR385Cp [Ashbya gossypii ATCC 10895]	1022.0	[0..1]	[1083..1]
gi\|71000154, gi\|... - gi\|71000154\|ref\|XP_754794.1\| alpha-mannosidase [Aspergillus fumigatus Af293], gi\|66852431\|gb\|EAL9275... gi\|159127803 - gi\|159127803\|gb\|EDP52918.1\| alpha-mannosidase [Aspergillus fumigatus A1163]	1020.0	[0..10]	[1081..20]
gi\|57338726 - gi\|57338726\|gb\|AAW49442.1\| mannosidase II [Aspergillus fumigatus]	1019.0	[0..10]	[1081..20]
gi\|16414637, gi\|... - pir\|\|AI1697 alpha-mannosidase homolog lin2123 [imported] - Listeria innocua (strain Clip11262), gi\|1... gi\|16801189 - gi\|16801189\|ref\|NP_471457.1\| hypothetical protein lin2123 [Listeria innocua Clip11262]	1015.0	[0..41]	[1082..2]

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Predicted Domain #1

Region A:
Residues: [1-191]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSEDIIYDP QFKPVQGIYE NRLRQFIDTG GDYHDLNLPK FYDKKRISLD HDHVKVWWYQ  60
   61 VSFERGSSPV SPDKRPSWKS IIERDKKGEL EFREANINQP FGPSWSTTWF KVKISLPEDW 120
  121 VKSNEQLLFQ WDCSNEGIVI DPKTLIPVTA FSGGERTEYV LPKTSDGKHF FYIEAGNNGM 180
  181 FGCGAGSTIN P

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [192-680]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDDNRFFHLR KADIVWPDLD ARALYIDFWM LGDAARELPG DSWQKHQARQ LGNAVMNLFD  60
   61 PNDRSSVRKC RELLQREYFD SFLESSKVYE QGESQVLTNV YGIGNCHIDT AWLWPFAETR 120
  121 RKIVRSWSSQ CTLMDRFPEY KFVASQAQQF KWLLEDHPEF FNKVLIPKIQ QSQFFAVGGT 180
  181 WVENDTNIPS GESLARQFFF GQRFFLKHFG LKSKIFWLPD TFGYSSQMPQ LCRLSGIDKF 240
  241 LTQKLSWNNI NSFPHSTFNW AGIDGSQLLT HMPPGNTYTA DSHFGDVLRT AKQNKTPEYY 300
  301 GSGLMLYGKG DGGGGPTEEM LQKMRRIRSM NNRNGNVIPK LQVGITVDEF YDDILKRTNQ 360
  361 GHDLPTWSGE LYFEFHRGTY TSQAQTKKLM RLSEIKLHDL EWIAAKTSVL YPDSYKYPSK 420
  421 QINELWENVL LCQFHDVLPG SCIEMVYKYE AVPMLHNVVK ECTSLIDKTV QFLQSQSKAD 480
  481 LVEMRTLTW

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	173.9794
Match:	1htyA
Description:	Golgi alpha-mannosidase II
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [681-966]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKPEKVSEEC SLNGSYTSSV TGYDDYIVLA NGKLKVIICK KTGVITSITD ETLGVEYLDT  60
   61 EHGRNKLGAN QFVIYDDKPL GWQAWDTELY SVNQYKYVTK PKKVQVSCNT KEKCAVEVIF 120
  121 QISEKCKIKS VISLNATAVT DAKLSKVDIS TTVENWDARN KFLKVEFPVN IRNDFASYET 180
  181 QFGITKRPTH YNTSWDVAKF EVCHHKFADY SEYSKGVSIL NDCKYGFSTH GNLMRLSLLR 240
  241 SPKAPDAHAD MGTHEIKYAI YPHRGALSSD TVKLAHEFNY CFKYKL

[Run NCBI BLAST on this sequence.]

Detection Method:	ab initio
Confidence:	10.12
Match:
Description:	No description for 1htyA was found.

Predicted Domain #4

Region A:
Residues: [967-1083]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKDIGMNFDD IISISGDENV ILSNIKRGED DSAVKSNYSL NPRDEQSIVV RVYESLGGES  60
   61 FASLNTTLNL KRIEKVDNLE MKVYKSLTAT RDESNHAINR IPIKLRPFEI ASFRLYF

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.290	N/A	N/A	b.1.1	Immunoglobulin

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits