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View Structure Prediction Details

Protein: VPS73
Organism: Saccharomyces cerevisiae
Length: 486 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VPS73.

Description E-value Query
Range		 Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 0.0 [20..485] [3..455]
KHT2_KLULC - Hexose transporter 2 OS=Kluyveromyces lactis GN=KHT2 PE=3 SV=1
 0.0 [27..484] [61..517]
GTR3_CHICK - Solute carrier family 2, facilitated glucose transporter member 3 OS=Gallus gallus GN=SLC2A3 PE=2 SV...
 0.0 [20..485] [3..455]
GTR1_RAT - Solute carrier family 2, facilitated glucose transporter member 1 OS=Rattus norvegicus GN=Slc2a1 PE=...
 0.0 [20..485] [4..458]
gi|115470211, gi... - gi|50508995|dbj|BAD31944.1| putative monosaccharide transport protein MST1 [Oryza sativa Japonica Gr...
gi|125556956 - gi|125556956|gb|EAZ02492.1| hypothetical protein OsI_24597 [Oryza sativa Indica Group]
gi|11991114 - gi|11991114|dbj|BAB19864.1| monosaccharide transporter 3 [Oryza sativa]
 0.0 [5..484] [1..479]
GTR1_MOUSE - Solute carrier family 2, facilitated glucose transporter member 1 OS=Mus musculus GN=Slc2a1 PE=1 SV=...
 0.0 [20..485] [4..458]
GTR1_BOVIN - Solute carrier family 2, facilitated glucose transporter member 1 OS=Bos taurus GN=SLC2A1 PE=1 SV=1
 0.0 [21..485] [5..458]
STC_RICCO - Sugar carrier protein C OS=Ricinus communis GN=STC PE=2 SV=1
 0.0 [4..484] [1..481]
GTR1_RABIT - Solute carrier family 2, facilitated glucose transporter member 1 OS=Oryctolagus cuniculus GN=SLC2A1...
 0.0 [20..485] [4..458]

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Predicted Domain #1
Region A:
Residues: [1-229] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRILSSASL LSNVSMPRQN KHKITKALCY AIIVASIGSI QFGYHLSELN APQQVLSCSE  60
   61 FDIPMEGYPY DRTWLGKRGY KQCIPLNDEQ IGIVTSVFCI GGILGSYFAT SLANIYGRKF 120
  121 SSLINCTLNI VGSLIIFNSN SYRGLIIGRI LVGISCGSLI VIIPLFIKEV APSGWEGLLG 180
  181 SMTQICIRLG VLLTQGIALP LTDSYRWRWI LFGSFLIAVL NFFMWFIVD

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [276-486] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LIEPTTTNSI SGSNSLWKYL RDRTNVKSRH VITVLLFGQQ FCGINSIVLY GTKIISQLYP  60
   61 QHAIRINFFI SMVNVLVTIL VSLLIHSLPR KPLLMTSTVL VSVTAFIMGI AMNHNKMNLL 120
  121 IVFSFIYMGV FTMGLNPLPF IIMREVSKPQ DMVLAQRYGT ICNWVGTFII AYTFPIIHDV 180
  181 LSGYVFIIFA IIACSISAFI WKKVPETKRS G

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 460.9897
Match: 1ja5A_
Description: No description for 1ja5A_ was found.

Predicted Domain #2
Region A:
Residues: [230-275] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESPKWLLAHG RVTDAKLSLC KLRGVTFDEA AQEIQDWQLQ IESGDP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 460.9897
Match: 1ja5A_
Description: No description for 1ja5A_ was found.

Predicted functions:

Term Confidence Notes
transporter activity 4.09176719149278 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.54194478414824 bayes_pls_golite062009
hexose phosphate transmembrane transporter activity 3.29248638217469 bayes_pls_golite062009
glucose-6-phosphate transmembrane transporter activity 3.29248638217469 bayes_pls_golite062009
sugar:hydrogen symporter activity 2.99050613058546 bayes_pls_golite062009
cation:sugar symporter activity 2.99050613058546 bayes_pls_golite062009
carbohydrate transmembrane transporter activity 2.62141276633776 bayes_pls_golite062009
sugar transmembrane transporter activity 2.47557586092261 bayes_pls_golite062009
ion transmembrane transporter activity 2.21266150105753 bayes_pls_golite062009
solute:hydrogen symporter activity 2.10485633822652 bayes_pls_golite062009
binding 1.89539096965643 bayes_pls_golite062009
cation transmembrane transporter activity 1.79369588808394 bayes_pls_golite062009
monosaccharide transmembrane transporter activity 1.6904339767429 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
polyol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.812001619402678 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle