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View Structure Prediction Details

Protein: MRH4
Organism: Saccharomyces cerevisiae
Length: 561 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MRH4.

Description E-value Query
Range
Subject
Range
DDX3_XENLA - Putative ATP-dependent RNA helicase an3 OS=Xenopus laevis GN=an3 PE=2 SV=1
0.0 [6..513] [109..609]
DDX3Y - DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
0.0 [6..513] [66..566]
DDX3X_MOUSE - ATP-dependent RNA helicase DDX3X OS=Mus musculus GN=Ddx3x PE=1 SV=3
0.0 [6..513] [66..568]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
0.0 [6..513] [109..609]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [6..513] [66..568]

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Predicted Domain #1
Region A:
Residues: [1-105]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLFFKPVIS PQWSFPVLLK IGVRSYAGGP RTKHKGNSPL ASVPTGSSNK NRKQKAKGKK  60
   61 GNKKNDPDQA FNFGEYGGLK KDVEMNMDST NKLIQKISNF DQLLI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [106-342]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPPVRDAVKE IISKESLKLQ DSRKKTSENI IPSPIQTVAI KRISKNLMDP KLQIHAIAAE  60
   61 TGSGKTMAYL IPLIDYLKRQ ELETPELWET LRKNVLIRSI ILVPTHELVD QVYETVSKTK 120
  121 TLLGLNSFKW DKATSYRDLL ENIKNRIDIL VTTPGKLLNL FSIRMITRPD KVLSKVGFVV 180
  181 LDEADTLLDR SWLEETHSAI KRIPNINHLI FCSATIPQEF NKTMQRLFPT VVPIMTP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 236.228787
Match: 1hv8A_
Description: Putative DEAD box RNA helicase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [343-507]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLHKLPFALD FKVINSALSP FKGSKIKALA QTLYAISNDD TEPGFEKRCI IFVNEKKNVP  60
   61 EIVNLLNKKF GHNAIGLTGE DTFEERSEKI MPFLSPPRPL SEVVAQSTSP PTSLKKFEIP 120
  121 DSNIVIGKLK NTNSNGTAPS NKSLHVLVTT DLMARGLNFK GVRNV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 236.228787
Match: 1hv8A_
Description: Putative DEAD box RNA helicase
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [508-561]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VLYDVPKTSI DLIHRVGRTA RMKQGGRVFM LTDSKTKSWA KALPKIIKKH QRLS

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.54
Match: 1fuuA
Description: Initiation factor 4a
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle