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View Structure Prediction Details

Protein: TIF4632
Organism: Saccharomyces cerevisiae
Length: 914 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TIF4632.

Description E-value Query
Range
Subject
Range
gi|114590776 - gi|114590776|ref|XP_001145549.1| PREDICTED: eukaryotic translation initiation factor 4 gamma, 1 isof...
430.0 [0..1] [875..1]
gi|38201619 - gi|38201619|ref|NP_004944.2| eukaryotic translation initiation factor 4 gamma, 1 isoform 4 [Homo sap...
428.0 [0..1] [875..1]

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Predicted Domain #1
Region A:
Residues: [1-110]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDQRGPPPP HPQQANGYKK FPPHDNQYSG ANNSQPNNHY NENLYSAREP HNNKQYQSKN  60
   61 GKYGTNKYNN RNNSQGNAQY YNNRFNNGYR LNNNDYNPAM LPGMQWPANY 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [111-166]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YAPQMYYIPQ QMVPVASPPY THQPLNTNPE PPSTPKTTKI EITTKTGERL NLKKFH

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 7.56
Match:
Description: No description for 1l8mA was found.

Predicted Domain #3
Region A:
Residues: [167-414]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEKKASKGEE KNDGVEQKSK SGTPFEKEAT PVLPANEAVK DTLTETSNEK STSEAENTKR  60
   61 LFLEQVRLRK AAMERKKNGL ISETEKKQET SNHDNTDTTK PNSVIESEPI KEAPKPTGEA 120
  121 NEVVIDGKSG ASVKTPQHVT GSVTKSVTFN EPENESSSQD VDELVKDDDT TEISDTTGGK 180
  181 TVNKSDDETI NSVITTEENT VKETEPSTSD IEMPTVSQLL ETLGKAQPIS DIYEFAYPEN 240
  241 VERPDIKY

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 9.96
Match:
Description: No description for 1jv2B was found.

Predicted Domain #4
Region A:
Residues: [415-472]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKPSVKYTYG PTFLLQFKDK LKFRPDPAWV EAVSSKIVIP PHIARNKPKD SGRFGGDF

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 9.96
Match:
Description: No description for 1jv2B was found.

Predicted Domain #5
Region A:
Residues: [473-555]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSPSMRGMDH TSSSRVSSKR RSKRMGDDRR SNRGYTSRKD REKAAEKAEE QAPKEEIAPL  60
   61 VPSANRWIPK SRVKKTEKKL APD

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 15.0
Match:
Description: No description for 1i3qA was found.

Predicted Domain #6
Region A:
Residues: [556-691]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKTELFDKEE VERKMKSLLN KLTLEMFDSI SSEILDIANQ SKWEDDGETL KIVIEQIFHK  60
   61 ACDEPHWSSM YAQLCGKVVK DLDPNIKDKE NEGKNGPKLV LHYLVARCHE EFEKGWADKL 120
  121 PAGEDGNPLE PEMMSD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 333.67837
Match: 1hu3A
Description: Eukaryotic initiation factor eIF4G
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [692-851]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EYYIAAAAKR RGLGLVRFIG YLYCLNLLTG KMMFECFRRL MKDLNNDPSE ETLESVIELL  60
   61 NTVGEQFEHD KFVTPQATLE GSVLLDNLFM LLQHIIDGGT ISNRIKFKLI DVKELREIKH 120
  121 WNSAKKDAGP KTIQQIHQEE EQLRQKKNSQ RSNSRFNNHN 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 333.67837
Match: 1hu3A
Description: Eukaryotic initiation factor eIF4G
Matching Structure (courtesy of the PDB):

Predicted Domain #8
Region A:
Residues: [852-914]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QSNSNRYSSN RRNMQNTQRD SFASTKTGSF RNNQRNARKV EEVSQAPRAN MFDALMNNDG  60
   61 DSD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle