YRC Public Data Repository - Protein Structure Prediction

Protein:	DST1
Organism:	Saccharomyces cerevisiae
Length:	309 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DST1.

Description	E-value	Query Range	Subject Range
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	2.0E-87	[5..308]	[4..300]
gi\|109086405 - gi\|109086405\|ref\|XP_001082935.1\| PREDICTED: transcription elongation factor A 1 isoform 2 [Macaca mu... gi\|61355862 - gi\|61355862\|gb\|AAX41184.1\| transcription elongation factor A 1 [synthetic construct] TCEA1 - transcription elongation factor A (SII), 1	2.0E-87	[5..308]	[4..300]
TCEA2_MOUSE - Transcription elongation factor A protein 2 OS=Mus musculus GN=Tcea2 PE=2 SV=2	4.0E-87	[4..308]	[5..298]
gi\|1325970, gi\|1... - gi\|50414699\|gb\|AAH77765.1\| XTFIIS.oB protein [Xenopus laevis], gi\|147905221\|ref\|NP_001081593.1\| TFII...	4.0E-86	[5..308]	[7..302]
TCEA2_RAT - Transcription elongation factor A protein 2 OS=Rattus norvegicus GN=Tcea2 PE=2 SV=1 gi\|712842 - gi\|712842\|dbj\|BAA02310.1\| transcription elongation factor S-II [Rattus sp.]	6.0E-86	[4..308]	[5..298]
gi\|171424, gi\|172773 - gi\|172773\|gb\|AAA88734.1\| DNA strand transferase alpha [Saccharomyces cerevisiae], gi\|171424\|gb\|AAA34...	1.0E-84	[1..309]	[1..309]

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Predicted Domain #1

Region A:
Residues: [1-103]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSKEVLVHV KNLEKNKSND AAVLEILHVL DKEFVPTEKL LRETKVGVEV NKFKKSTNVE  60
   61 ISKLVKKMIS SWKDAINKNK RSRQAQQHHQ DHAPGNAEDK TTV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	330.502279
Match:	1eo0A_
Description:	Transcription elongation factor TFIIS N-domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [104-190]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GESVNGVQQP ASSQSDAMKQ DKYVSTKPRN SKNDGVDTAI YHHKLRDQVL KALYDVLAKE  60
   61 SEHPPQSILH TAKAIESEMN KVNNCDT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	574.66807
Match:	1enwA_
Description:	Elongation factor TFIIS domain 2
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [191-258]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NEAAYKARYR IIYSNVISKN NPDLKHKIAN GDITPEFLAT CDAKDLAPAP LKQKIEEIAK  60
   61 QNLYNAQG

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	13.27
Match:	1enwA
Description:	Elongation factor TFIIS domain 2
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [259-309]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATIERSVTDR FTCGKCKEKK VSYYQLQTRS ADEPLTTFCT CEACGNRWKF S

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	155.08661
Match:	1tfi__
Description:	Transcriptional factor SII, C-terminal domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits