YRC Public Data Repository - Protein Structure Prediction

Protein:	HOP2
Organism:	Saccharomyces cerevisiae
Length:	218 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HOP2.

Description	E-value	Query Range	Subject Range
HOP2 - Meiosis-specific protein that localizes to chromosomes, preventing synapsis between nonhomologous ch... HOP2_YEAST - Homologous-pairing protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HOP2 PE=1 S...	4.0E-51	[1..218]	[1..218]
gi\|45198992, gi\|... - gi\|45198992\|ref\|NP_986021.1\| AFR474Wp [Ashbya gossypii ATCC 10895], gi\|44985067\|gb\|AAS53845.1\| AFR47... gi\|44985067 - gi\|44985067\|gb\|AAS53845.1\| AFR474Wp [Ashbya gossypii ATCC 10895]	1.0E-47	[1..211]	[75..286]
HOP2_MOUSE - Homologous-pairing protein 2 homolog OS=Mus musculus GN=Psmc3ip PE=1 SV=1	1.0E-46	[10..205]	[3..198]
PSMC3IP - PSMC3 interacting protein	8.0E-43	[10..205]	[3..198]
HOP2_SCHPO - Homologous-pairing protein 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=meu13 PE=1 SV... meu13 - Tat binding protein 1(TBP-1)-interacting protein (TBPIP) homolog	3.0E-35	[4..206]	[2..205]
HOP2_ARATH - Homologous-pairing protein 2 homolog OS=Arabidopsis thaliana GN=HOP2 PE=1 SV=1	8.0E-30	[1..204]	[1..192]

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Predicted Domain #1

Region A:
Residues: [1-218]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPKKKSNDR AIQAKGSEAE QLIEDYLVSQ YKPFSVNDIV QNLHNKVTKT TATKALENLV  60
   61 NEKRIVSKTF GKIIIYSCNE QDTALPSNID PSQFDFETVL QLRNDLIELE RDKSTAKDAL 120
  121 DSVTKEPENE DLLTIIENEE NELKKIESKL QSLQDDWDPA NDEIVKRIMS EDTLLQKEIT 180
  181 KRSKICKNLI ATIKDSVCPK NMNEFLVCIL NIFRDLFF

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [79-218]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NEQDTALPSN IDPSQFDFET VLQLRNDLIE LERDKSTAKD ALDSVTKEPE NEDLLTIIEN  60
   61 EENELKKIES KLQSLQDDWD PANDEIVKRI MSEDTLLQKE ITKRSKICKN LIATIKDSVC 120
  121 PKNMNEFLVC ILNIFRDLFF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	4.045757
Match:	1i84S
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits