YRC Public Data Repository - Protein Structure Prediction

Protein:	PMA1
Organism:	Saccharomyces cerevisiae
Length:	918 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PMA1.

Description	E-value	Query Range	Subject Range
AT1A3_CHICK - Sodium/potassium-transporting ATPase subunit alpha-3 OS=Gallus gallus GN=ATP1A3 PE=2 SV=1	0.0	[31..886]	[3..955]
AT1A1_HORSE - Sodium/potassium-transporting ATPase subunit alpha-1 OS=Equus caballus GN=ATP1A1 PE=3 SV=1	0.0	[1..886]	[1..966]
gi\|447739 - gi\|447739\|prf\|\|1915304A nylB upstream ORF	0.0	[2..886]	[20..1004]
PMA1_YEAST - Plasma membrane ATPase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PMA1 PE=1 SV=2 PMA1 - Plasma membrane H+-ATPase, pumps protons out of the cell; major regulator of cytoplasmic pH and plas...	0.0	[1..918]	[1..918]
gi\|11067034 - gi\|11067034\|gb\|AAG27060.1\| Na+/K+ ATPase alpha subunit isoform 8 [Danio rerio]	0.0	[3..886]	[8..969]
gi\|1364218 - gi\|1364218\|emb\|CAA26582.1\| unnamed protein product [Ovis aries]	0.0	[3..886]	[3..961]
gi\|148692351, gi... - gi\|21450321\|ref\|NP_659170.1\| Na+/K+ -ATPase alpha 3 subunit [Mus musculus], gi\|18044918\|gb\|AAH20177....	0.0	[24..886]	[3..958]

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Predicted Domain #1

Region A:
Residues: [1-107]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDTSSSSSS SSASSVSAHQ PTQEKPAKTY DDAASESSDD DDIDALIEEL QSNHGVDDED  60
   61 SDNDGPVAAG EARPVPEEYL QTDPSYGLTS DEVLKRRKKY GLNQMAD

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [178-280]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTAVVIRDGQ LVEIPANEVV PGDILQLEDG TVIPTDGRIV TEDCFLQIDQ SAITGESLAV  60
   61 DKHYGDQTFS SSTVKRGEGF MVVTATGDNT FVGRAAALVN KAA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1306.9897
Match:	1eulA_
Description:	Calcium ATPase, transduction domain A; Calcium ATPase, catalytic domain P; Calcium ATPase; Calcium ATPase, transmembrane domain M

Predicted Domain #2

Region A:
Residues: [108-167]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKESLVVKFV MFFVGPIQFV MEAAAILAAG LSDWVDFGVI CGLLMLNAGV GFVQEFQAGS  60
   61

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [281-345]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGQGHFTEVL NGIGIILLVL VIATLLLVWT ACFYRTNGIV RILRYTLGIT IIGVPVGLPA  60
   61 VVTTT

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [684-918]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IFHRMYSYVV YRIALSLHLE IFLGLWIAIL DNSLDIDLIV FIAIFADVAT LAIAYDNAPY  60
   61 SPKPVKWNLP RLWGMSIILG IVLAIGSWIT LTTMFLPKGG IIQNFGAMNG IMFLQISLTE 120
  121 NWLIFITRAA GPFWSSIPSW QLAGAVFAVD IIATMFTLFG WWSENWTDIV TVVRVWIWSI 180
  181 GIFCVLGGFY YEMSTSEAFD RLMNGKPMKE KKSTRSVEDF MAAMQRVSTQ HEKET

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1306.9897
Match:	1eulA_
Description:	Calcium ATPase, transduction domain A; Calcium ATPase, catalytic domain P; Calcium ATPase; Calcium ATPase, transmembrane domain M

Predicted Domain #3

Region A:
Residues: [168-177]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IVDELKKTLA

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [346-385]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVGAAYLAK KQAIVQKLSA IESLAGVEIL CSDKTGTLTK

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [536-683]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRDDTAQTVS EARHLGLRVK MLTGDAVGIA KETCRQLGLG TNIYNAERLG LGGGGDMPGS  60
   61 ELADFVENAD GFAEVFPQHK YRVVEILQNR GYLVAMTGDG VNDAPSLKKA DTGIAVEGAT 120
  121 DAARSAADIV FLAPGLSAII DALKTSRQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1306.9897
Match:	1eulA_
Description:	Calcium ATPase, transduction domain A; Calcium ATPase, catalytic domain P; Calcium ATPase; Calcium ATPase, transmembrane domain M

Predicted Domain #4

Region A:
Residues: [386-535]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKLSLHEPYT VEGVSPDDLM LTACLAASRK KKGLDAIDKA FLKSLKQYPK AKDALTKYKV  60
   61 LEFHPFDPVS KKVTAVVESP EGERIVCVKG APLFVLKTVE EDHPIPEDVH ENYENKVAEL 120
  121 ASRGFRALGV ARKRGEGHWE ILGVMPCMDP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1306.9897
Match:	1eulA_
Description:	Calcium ATPase, transduction domain A; Calcium ATPase, catalytic domain P; Calcium ATPase; Calcium ATPase, transmembrane domain M

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits