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View Structure Prediction Details

Protein: DUG1
Organism: Saccharomyces cerevisiae
Length: 481 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DUG1.

Description E-value Query
Range
Subject
Range
gi|15620780 - gi|15620780|emb|CAC69883.1| glutamate carboxypeptidase [Homo sapiens]
0.0 [2..480] [1..475]
CNDP2_MOUSE - Cytosolic non-specific dipeptidase OS=Mus musculus GN=Cndp2 PE=1 SV=1
0.0 [2..479] [1..474]
DUG1 - Cys-Gly metallo-di-peptidase; forms a complex with Dug2p and Dug3p to degrade glutathione (GSH) and ...
DUG1_YEAST - Cys-Gly metallodipeptidase DUG1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DUG1 PE=...
gi|207345611 - gi|207345611|gb|EDZ72376.1| YFR044Cp-like protein [Saccharomyces cerevisiae AWRI1631]
7.0E-97 [1..481] [1..481]
DUG1_SCHPO - Cys-Gly metallodipeptidase dug1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=dug1 PE=2 ...
SPBC1198.08 - dipeptidase Dug1
2.0E-94 [4..478] [2..472]
pes-9 - Yeast hypothetical 52.9 KD protein like status:Confirmed UniProt:O18000 protein_id:CAB07646.1
2.0E-91 [1..477] [1..472]
gi|25312288 - pir||C84134 hypothetical protein BH3875 [imported] - Bacillus halodurans (strain C-125)
gi|15616437, gi|... - gi|15616437|ref|NP_244742.1| hypothetical protein BH3875 [Bacillus halodurans C-125], gi|10176500|db...
7.0E-84 [5..481] [1..458]
gi|25520910 - pir||G97371 argE/dapE/acy1 family protein [imported] - Agrobacterium tumefaciens (strain C58, Cereon...
gi|15154979, gi|... - gi|15887462|ref|NP_353143.1| hypothetical protein AGR_C_165 [Agrobacterium tumefaciens str. C58], gi...
8.0E-84 [2..477] [45..506]
gi|25527699 - pir||AE3480 aminoacylase (EC 3.5.1.14) [imported] - Brucella melitensis (strain 16M)
gi|17988110, gi|... - gi|17988110|ref|NP_540744.1| hypothetical protein BMEI1827 [Brucella melitensis 16M], gi|17983863|gb...
1.0E-83 [1..477] [13..480]
gi|15073105 - gi|15073105|emb|CAC41564.1| Putative succinyl-diaminopimelate desuccinylase [Sinorhizobium meliloti ...
gi|15963930 - gi|15963930|ref|NP_384283.1| hypothetical protein SMc02852 [Sinorhizobium meliloti 1021]
1.0E-83 [1..476] [1..462]

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Predicted Domain #1
Region A:
Residues: [1-217]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHSLTSVFQ KIDSLKPQFF SRLTKAIQIP AVSSDESLRS KVFDKAKFIS EQLSQSGFHD  60
   61 IKMVDLGIQP PPISTPNLSL PPVILSRFGS DPSKKTVLVY GHYDVQPAQL EDGWDTEPFK 120
  121 LVIDEAKGIM KGRGVTDDTG PLLSWINVVD AFKASGQEFP VNLVTCFEGM EESGSLKLDE 180
  181 LIKKEANGYF KGVDAVCISD NYWLGTKKPV LTYGLRG

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [387-481]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAYWVSDPFN AQFTAAKKAT KLVYGVDPDF TREGGSIPIT LTFQDALNTS VLLLPMGRGD  60
   61 DGAHSINEKL DISNFVGGMK TMAAYLQYYS ESPEN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.522879
Match: 1cg2A_
Description: Carboxypeptidase G2, catalytic domain; Carboxypeptidase G2
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [218-386]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CNYYQTIIEG PSADLHSGIF GGVVAEPMID LMQVLGSLVD SKGKILIDGI DEMVAPLTEK  60
   61 EKALYKDIEF SVEELNAATG SKTSLYDKKE DILMHRWRYP SLSIHGVEGA FSAQGAKTVI 120
  121 PAKVFGKFSI RTVPDMDSEK LTSLVQKHCD AKFKSLNSPN KCRTELIHD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.522879
Match: 1cg2A_
Description: Carboxypeptidase G2, catalytic domain; Carboxypeptidase G2
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle