YRC Public Data Repository - Protein Structure Prediction

Protein:	DDI3, DDI2
Organism:	Saccharomyces cerevisiae
Length:	225 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DDI3, DDI2.

Description	E-value	Query Range	Subject Range
DDI3_YEAST, DDI2... - Cyanamide hydratase DDI3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DDI3 PE=1 SV=1,... DDI3, DDI2 - Protein of unknown function; expression is induced over 100-fold by DNA damage; induction decreased ... gi\|207342008 - gi\|207342008\|gb\|EDZ69904.1\| YNL335Wp-like protein [Saccharomyces cerevisiae AWRI1631]	9.0E-66	[1..225]	[1..225]
CYAH_MYRVE - Cyanamide hydratase OS=Myrothecium verrucaria GN=CAH PE=1 SV=1	1.0E-43	[34..221]	[45..238]
RNY_CLOAB - Ribonuclease Y OS=Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM ... RNY_CLOAB, YI16_... - (Q97I38) Hypothetical UPF0144 protein CAC1816, UPF0144 protein CA_C1816 - Clostridium acetobutylicum...	4.0E-37	[7..198]	[283..453]
Y1672_CLOPE, YG7... - (Q8XJT1) Hypothetical UPF0144 protein CPE1672, UPF0144 protein CPE1672 - Clostridium perfringens gi\|18145335, gi\|... - gi\|18310654\|ref\|NP_562588.1\| phosphodiesterase [Clostridium perfringens str. 13], gi\|18145335\|dbj\|BA...	1.0E-35	[7..198]	[299..469]
Y1857_THEMA, CNP... - (Q9X2H2) Hypothetical UPF0144 protein TM1857, UPF0144 protein TM_1857 - Thermotoga maritima, Ribonuc... RNY_THEMA - Ribonuclease Y OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) GN=rny PE=3 ...	4.0E-35	[6..198]	[276..447]
gi\|14021842, gi\|... - gi\|14021842\|dbj\|BAB48453.1\| mlr0982 [Mesorhizobium loti MAFF303099], gi\|13471098\|ref\|NP_102667.1\| hy...	1.0E-31	[21..202]	[4..180]
gi\|225371029, gi... - gi\|225552031\|ref\|ZP_03772971.1\| conserved hypothetical protein [Borrelia sp. SV1], gi\|225371029\|gb\|E... gi\|216264862, gi... - gi\|216264862\|ref\|ZP_03436854.1\| conserved hypothetical protein [Borrelia burgdorferi 156a], gi\|21598... gi\|223885647, gi... - gi\|223888831\|ref\|ZP_03623422.1\| conserved hypothetical protein [Borrelia burgdorferi 64b], gi\|223885... gi\|224512183, gi... - gi\|224532907\|ref\|ZP_03673519.1\| conserved hypothetical protein [Borrelia burgdorferi WI91-23], gi\|22... RNY_BORBU, CNPD_... - UPF0144 protein BB_0504 - Borrelia burgdorferi (Lyme disease spirochete), Ribonuclease Y OS=Borrelia... gi\|226321814, gi... - gi\|226321814\|ref\|ZP_03797340.1\| conserved hypothetical protein [Borrelia burgdorferi Bol26], gi\|2262... gi\|226320985, gi... - gi\|226320985\|ref\|ZP_03796530.1\| conserved hypothetical protein [Borrelia burgdorferi 29805], gi\|2262... RNY_BORBU - Ribonuclease Y OS=Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680) GN=rny PE=3...	8.0E-31	[9..197]	[279..448]
gi\|21219007, gi\|... - gi\|6002362\|emb\|CAB56727.1\| conserved hypothetical protein SCF76.07 [Streptomyces coelicolor A3(2)], ...	3.0E-29	[23..194]	[37..204]
RNY_BACHD, CNPD_... - (Q9KAB2) Hypothetical UPF0144 protein BH2378, UPF0144 protein BH2378 - Bacillus halodurans, Ribonucl... RNY_BACHD - Ribonuclease Y OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-12...	5.0E-29	[8..198]	[291..460]

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Predicted Domain #1

Region A:
Residues: [1-225]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQYGFVRVP REVEKAIPVV NAPRPRAVVP PPNSETARLV REYAAKELTA PVLNHSLRVF  60
   61 QYSVAIIRDQ FPAWDLDQEV LYVTCLLHDI ATTDKNMRAT KMSFEYYGGI LSRELVFNAT 120
  121 GGNQDYADAV TEAIIRHQDL TGTGYITTLG LILQIATTLD NVGSNTDLIH IDTVSAINEQ 180
  181 FPRLHWLSCF ATVVDTENSR KPWGHTSSLG DDFSKKVICN TFGYN

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	10.455932
Match:	PF01966
Description:	HD domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.304053477190873	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: