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View Structure Prediction Details

Protein: DEG1
Organism: Saccharomyces cerevisiae
Length: 442 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DEG1.

Description E-value Query
Range
Subject
Range
gi|31981121, gi|... - gi|31981121|ref|NP_075781.2| pseudouridine synthase 3 [Mus musculus], gi|26347775|dbj|BAC37536.1| un...
428.0 [0..29] [440..4]
gi|16550495 - gi|16550495|dbj|BAB70990.1| unnamed protein product [Homo sapiens]
428.0 [0..27] [440..3]
gi|114641137 - gi|114641137|ref|XP_001148378.1| PREDICTED: pseudouridylate synthase 3 [Pan troglodytes]
426.0 [0..27] [440..3]
gi|109109191 - gi|109109191|ref|XP_001111887.1| PREDICTED: pseudouridylate synthase 3 [Macaca mulatta]
418.0 [0..29] [440..4]
gi|57085889 - gi|57085889|ref|XP_536533.1| PREDICTED: similar to tRNA pseudouridine synthase 3 (tRNA-uridine isome...
416.0 [0..27] [440..3]

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Predicted Domain #1
Region A:
Residues: [1-90]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNFIRRLVG KMKAISTGTN AIVSKKDSIY ANWSKEQLIR RITELENANK PHSEKFQHIE  60
   61 DNKKRKISQE EVTRSKAKKA PKKFDFSKHN 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.212 b.92.1 Composite domain of metallo-dependent hydrolases

Predicted Domain #2
Region A:
Residues: [91-354]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TRFIALRFAY LGWNYNGLAV QKEYTPLPTV EGTILEAMNK CKLVPSMVLQ DYKFSRCGRT  60
   61 DKGVSAMNQV ISLEVRSNLT DEEQRDPTND SREIPYVHVL NQLLPDDIRI SAVCLRPPPN 120
  121 FDARFSCVHR HYKYIFNGKN LNIEKMSKAA SYFVGERDFR NFCKLDGSKQ ITNFKRTIIS 180
  181 SKILPLSETF YCFDLVGSAF LWHQVRCMMA ILFLVGQSLE VPEIVLRLTD IEKTPQRPVY 240
  241 EMANDIPLLL YDCKFPEMDW QEPT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 78.0
Match: 2nqpA
Description: No description for 2nqpA was found.

Predicted Domain #3
Region A:
Residues: [355-442]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VDDYKAIKFT TATEALTLHY ELKAAVCNIF KDVLPTANTN NFSKTIINLG DGRGKVVGTY  60
   61 VKLEDRSVME PVEVVNAKYS KKKNNKNK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.898 d.58.4 Dimeric alpha+beta barrel
View Download 0.892 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.892 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.881 d.74.3 RBP11-like subunits of RNA polymerase
View Download 0.881 d.74.3 RBP11-like subunits of RNA polymerase
View Download 0.864 d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain
View Download 0.808 d.240.1 Description not found.
View Download 0.778 d.58.12 eEF-1beta-like
View Download 0.776 d.58.20 NAD-binding domain of HMG-CoA reductase


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle