YRC Public Data Repository - Protein Structure Prediction

Protein:	FAU1
Organism:	Saccharomyces cerevisiae
Length:	211 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FAU1.

Description	E-value	Query Range	Subject Range
FAU1 - 5,10-methenyltetrahydrofolate synthetase, involved in folic acid biosynthesis FTHC_YEAST - 5-formyltetrahydrofolate cyclo-ligase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FA...	6.0E-55	[1..211]	[1..211]
gi\|126510113, gi... - gi\|153819332\|ref\|ZP_01971999.1\| conserved hypothetical protein [Vibrio cholerae NCTC 8457], gi\|12651... gi\|153822866, gi... - gi\|229512342\|ref\|ZP_04401821.1\| 5-formyltetrahydrofolate cyclo-ligase [Vibrio cholerae B33], gi\|2293... gi\|75829168, gi\|... - gi\|75829168\|ref\|ZP_00758481.1\| COG0212: 5-formyltetrahydrofolate cyclo-ligase [Vibrio cholerae MO10]... gi\|227082599, gi... - gi\|227082599\|ref\|YP_002811150.1\| hypothetical protein VCM66_2401 [Vibrio cholerae M66-2], gi\|2270104... gi\|229507463, gi... - gi\|229507463\|ref\|ZP_04396968.1\| 5-formyltetrahydrofolate cyclo-ligase [Vibrio cholerae BX 330286], g... gi\|229519478, gi... - gi\|229519478\|ref\|ZP_04408921.1\| 5-formyltetrahydrofolate cyclo-ligase [Vibrio cholerae RC9], gi\|2293... gi\|229369623, gi... - gi\|229606968\|ref\|YP_002877616.1\| 5-formyltetrahydrofolate cyclo-ligase [Vibrio cholerae MJ-1236], gi... gi\|11278428 - pir\|\|A82072 conserved hypothetical protein VC2479 [imported] - Vibrio cholerae (strain N16961 serogr... gi\|121547403, gi... - gi\|121590762\|ref\|ZP_01678092.1\| conserved hypothetical protein [Vibrio cholerae 2740-80], gi\|1215474... gi\|9657058, gi\|1... - gi\|9657058\|gb\|AAF95621.1\| conserved hypothetical protein [Vibrio cholerae O1 biovar El Tor str. N169... gi\|124118870, gi... - gi\|153222433\|ref\|ZP_01953167.1\| conserved hypothetical protein [Vibrio cholerae MAK 757], gi\|1241188...	2.0E-45	[1..209]	[1..194]
gi\|221314736 - gi\|221314736\|ref\|ZP_03596541.1\| hypothetical protein BsubsN3_13547 [Bacillus subtilis subsp. subtili... gi\|221319659 - gi\|221319659\|ref\|ZP_03600953.1\| hypothetical protein BsubsJ_13468 [Bacillus subtilis subsp. subtilis... gi\|221323936 - gi\|221323936\|ref\|ZP_03605230.1\| hypothetical protein BsubsS_13602 [Bacillus subtilis subsp. subtilis... YQGN_BACSU - Uncharacterized protein yqgN OS=Bacillus subtilis GN=yqgN PE=1 SV=1 YQGN_BACSU - Uncharacterized protein YqgN OS=Bacillus subtilis (strain 168) GN=yqgN PE=1 SV=1	7.0E-45	[3..210]	[1..186]
gi\|165923168, gi... - gi\|165924968\|ref\|ZP_02220800.1\| 5,10-methenyltetrahydrofolate synthetase [Yersinia pestis biovar Ori... gi\|229697191, gi... - gi\|229840825\|ref\|ZP_04460984.1\| predicted ligase [Yersinia pestis biovar Orientalis str. PEXU2], gi\|... gi\|229690925, gi... - gi\|229842615\|ref\|ZP_04462770.1\| predicted ligase [Yersinia pestis biovar Orientalis str. India 195],... gi\|166206102, gi... - gi\|166212810\|ref\|ZP_02238845.1\| 5,10-methenyltetrahydrofolate synthetase [Yersinia pestis biovar Ant... gi\|165990842, gi... - gi\|166010356\|ref\|ZP_02231254.1\| 5,10-methenyltetrahydrofolate synthetase [Yersinia pestis biovar Ant... gi\|167418930, gi... - gi\|167418930\|ref\|ZP_02310683.1\| 5,10-methenyltetrahydrofolate synthetase [Yersinia pestis biovar Ori... gi\|167050600, gi... - gi\|167399892\|ref\|ZP_02305410.1\| 5,10-methenyltetrahydrofolate synthetase [Yersinia pestis biovar Ant... gi\|167055732, gi... - gi\|167425332\|ref\|ZP_02317085.1\| 5,10-methenyltetrahydrofolate synthetase [Yersinia pestis biovar Med... gi\|165914708, gi... - gi\|89104318\|ref\|ZP_01176864.1\| COG0212: 5-formyltetrahydrofolate cyclo-ligase [Yersinia pestis biova... gi\|108778264, gi... - gi\|108806351\|ref\|YP_650267.1\| putative 5-formyltetrahydrofolate cyclo-ligase-family protein [Yersini... gi\|108813272, gi... - gi\|229903729\|ref\|ZP_04518842.1\| predicted ligase [Yersinia pestis Nepal516], gi\|229679499\|gb\|EEO7560... gi\|162354641, gi... - gi\|77635841\|ref\|ZP_00797921.1\| COG0212: 5-formyltetrahydrofolate cyclo-ligase [Yersinia pestis Angol... gi\|25302309 - pir\|\|AB0112 probable 5-formyltetrahydrofolate cyclo-ligase-family protein YPO0913 [imported] - Yersi... gi\|45438213, gi\|... - gi\|45443344\|ref\|NP_994883.1\| putative 5-formyltetrahydrofolatecyclo-ligase-family protein [Yersinia ... gi\|22127176, gi\|... - gi\|22127176\|ref\|NP_670599.1\| ligase [Yersinia pestis KIM], gi\|21960240\|gb\|AAM86850.1\|AE013931_3 puta... gi\|16121218, gi\|... - gi\|218928086\|ref\|YP_002345961.1\| putative 5-formyltetrahydrofolate cyclo-ligase-family protein [Yers... gi\|149367077, gi... - gi\|149367077\|ref\|ZP_01889110.1\| putative 5-formyltetrahydrofolate cyclo-ligase-family protein [Yersi... gi\|145209604, gi... - gi\|145597908\|ref\|YP_001161984.1\| 5-formyltetrahydrofolate cyclo-ligase-family protein [Yersinia pest... gi\|229837601, gi... - gi\|229837601\|ref\|ZP_04457763.1\| predicted ligase [Yersinia pestis Pestoides A], gi\|229704289\|gb\|EEO9...	2.0E-44	[3..209]	[10..198]
gi\|25302307 - gi\|25302307\|pir\|\|B85947 probable ligase ygfA [imported] - Escherichia coli (strain O157:H7, substrai... gi\|15803446, gi\|... - gi\|15803446\|ref\|NP_289479.1\| putative ligase [Escherichia coli O157:H7 EDL933], gi\|12517441\|gb\|AAG58...	2.0E-42	[11..209]	[2..182]
gi\|16421613, gi\|... - gi\|16766362\|ref\|NP_461977.1\| putative ligase [Salmonella typhimurium LT2], gi\|16421613\|gb\|AAL21936.1... lcl\|NC_016856.1_... - [gene=ygfA] [protein=putative ligase] [protein_id=YP_005239201.1] [location=3241489..3242037]	3.0E-42	[11..209]	[2..182]
gi\|168210372, gi... - gi\|170711556\|gb\|EDT23738.1\| 5-formyltetrahydrofolate cyclo-ligase family protein [Clostridium perfri... gi\|18311306, gi\|... - gi\|18311306\|ref\|NP_563240.1\| 5-formyltetrahydrofolate cyclo-ligase family protein [Clostridium perfr...	4.0E-41	[2..208]	[1..188]
MTHFS_MOUSE - 5-formyltetrahydrofolate cyclo-ligase OS=Mus musculus GN=Mthfs PE=2 SV=2	5.0E-41	[3..204]	[9..199]
YGFA_HAEIN, Y858... - (P44905) Protein HI0858, Uncharacterized protein HI_0858 OS=Haemophilus influenzae GN=HI_0858 PE=1 S... 5FCL_HAEIN - 5-formyltetrahydrofolate cyclo-ligase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW2...	6.0E-40	[1..201]	[1..185]
MTHFS - 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)	2.0E-39	[3..204]	[9..199]

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Predicted Domain #1

Region A:
Residues: [1-211]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATKQLLRRQ IKRVINALDY DIIAAESHTI SQAVRSLIAS ANSRRVACYM SMDKGEVTTG  60
   61 EIIKNLFQDG QEVFLPRCTH TSESKHFKLR EDHHPHLIFH RMSSLKMVRD LKPQGPYQLK 120
  121 EPEPHIEESD ILDVVLVPGV AFDIKTGARM GHGAGYYDDF FQRYKILHEG QKPLLVGLCL 180
  181 MEQVASPIPL EKHDYSMDCI VCGDGSIHWF Q

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	75.552842
Match:	PF01812
Description:	5-formyltetrahydrofolate cyclo-ligase family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits