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View Structure Prediction Details

Protein: MAG1
Organism: Saccharomyces cerevisiae
Length: 296 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MAG1.

Description E-value Query
Range
Subject
Range
MAG_YEAST - DNA-3-methyladenine glycosylase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MAG1 PE=...
MAG1 - 3-methyl-adenine DNA glycosylase involved in protecting DNA against alkylating agents; initiates bas...
2.0E-59 [1..296] [1..296]
gi|16224030 - gi|16224030|gb|AAL15611.1|AF322256_32 endonuclease/N-glycosylase [Streptomyces antibioticus]
3.0E-45 [55..289] [27..249]
gi|10174315, gi|... - gi|15614261|ref|NP_242564.1| endonuclease III (DNA repair) [Bacillus halodurans C-125], gi|10174315|...
gi|25292133 - pir||B83862 endonuclease III (DNA repair) nth [imported] - Bacillus halodurans (strain C-125)
3.0E-45 [70..273] [17..201]
gi|25292136 - pir||G96984 probable endonuclease, gene nth [imported] - Clostridium acetobutylicum
gi|15893977, gi|... - gi|15893977|ref|NP_347326.1| endonuclease, gene nth [Clostridium acetobutylicum ATCC 824], gi|150235...
4.0E-45 [69..273] [15..199]
gi|229903773, gi... - gi|229903773|ref|ZP_04518886.1| adenine DNA glycosylase [Yersinia pestis Nepal516], gi|229679543|gb|...
gi|15979021, gi|... - gi|218928123|ref|YP_002345998.1| adenine DNA glycosylase [Yersinia pestis CO92], gi|16121255|ref|NP_...
gi|25292160 - pir||AH0116 A/G-specific adenine glycosylase (EC 3.2.2.-) [imported] - Yersinia pestis (strain CO92)
gi|149290654, gi... - gi|149367040|ref|ZP_01889073.1| A/G-specific adenine glycosylase [Yersinia pestis CA88-4125], gi|149...
gi|229837648, gi... - gi|229837648|ref|ZP_04457810.1| adenine DNA glycosylase [Yersinia pestis Pestoides A], gi|229704336|...
gi|229842567, gi... - gi|229842567|ref|ZP_04462722.1| adenine DNA glycosylase [Yersinia pestis biovar Orientalis str. Indi...
gi|229697238, gi... - gi|229840872|ref|ZP_04461031.1| adenine DNA glycosylase [Yersinia pestis biovar Orientalis str. PEXU...
4.0E-45 [58..273] [6..204]
gi|17231462, gi|... - gi|17231462|ref|NP_488010.1| endonuclease III [Nostoc sp. PCC 7120], gi|17133104|dbj|BAB75669.1| end...
gi|25292149 - pir||AC2302 endonuclease III [imported] - Nostoc sp. (strain PCC 7120)
4.0E-45 [50..273] [5..209]
gi|5822134, gi|2... - gi|5822134|pdb|1MUY|A Chain A, Catalytic Domain Of Muty From Escherichia Coli, gi|27065207|pdb|1KG3|...
1.0E-44 [59..273] [11..204]
MUTY_ECOLI - A/G-specific adenine glycosylase (EC 3.2.2.-) - Escherichia coli
EG10627 - adenine DNA glycosylase / Adenine DNA glycosylase, G-A mismatched DNA repair; 2-hydroxyadenine glyco...
gi|89109738, gi|... - gi|89109738|ref|AP_003518.1| adenine DNA glycosylase [Escherichia coli str. K-12 substr. W3110], gi|...
gi|169753726, gi... - gi|170018798|ref|YP_001723752.1| adenine DNA glycosylase [Escherichia coli ATCC 8739], gi|169753726|...
gi|75515259 - gi|75515259|ref|ZP_00737443.1| COG1194: A/G-specific DNA glycosylase [Escherichia coli 53638]
gi|169890348, gi... - gi|170082513|ref|YP_001731833.1| adenine DNA glycosylase [Escherichia coli str. K-12 substr. DH10B],...
gi|75196910 - gi|75196910|ref|ZP_00706980.1| COG1194: A/G-specific DNA glycosylase [Escherichia coli HS]
EG10627 - adenine DNA glycosylase / Adenine DNA glycosylase, G-A mismatched DNA repair; 2-hydroxyadenine glyco...
gi|124526139, gi... - gi|124526139|ref|ZP_01698144.1| A/G-specific adenine glycosylase [Escherichia coli B], gi|124502243|...
gi|238859929, gi... - gi|238902083|ref|YP_002927879.1| adenine DNA glycosylase [Escherichia coli BW2952], gi|238859929|gb|...
gi|242378487, gi... - gi|251786214|ref|YP_003000518.1| hypothetical protein B21_02754 [Escherichia coli BL21], gi|24237848...
gi|254289631, gi... - gi|254289631|ref|YP_003055379.1| adenine DNA glycosylase [Escherichia coli BL21(DE3)], gi|253978938|...
gi|253974772, gi... - gi|254162871|ref|YP_003045979.1| adenine DNA glycosylase [Escherichia coli B str. REL606], gi|253974...
1.0E-44 [59..273] [11..204]
gi|47096477, gi|... - gi|47096477|ref|ZP_00234069.1| endonuclease III [Listeria monocytogenes str. 1/2a F6854], gi|4701513...
gi|16803933 - gi|16803933|ref|NP_465418.1| endonuclease III (DNA repair) [Listeria monocytogenes EGD-e]
gi|16411347, gi|... - pir||AF1311 probable endonuclease III (DNA repair) [imported] - Listeria monocytogenes (strain EGD-e...
gi|254912452 - gi|254912452|ref|ZP_05262464.1| endonuclease III (DNA repair) [Listeria monocytogenes J2818]
gi|254936779 - gi|254936779|ref|ZP_05268476.1| endonuclease III (DNA repair) [Listeria monocytogenes F6900]
gi|126943672, gi... - gi|254899409|ref|ZP_05259333.1| endonuclease III (DNA repair) [Listeria monocytogenes J0161], gi|153...
gi|254827221, gi... - gi|254827221|ref|ZP_05231908.1| endonuclease III (DNA repair) [Listeria monocytogenes FSL N3-165], g...
2.0E-44 [70..279] [17..208]
gi|15678789, gi|... - gi|2621854|gb|AAB85267.1| endonuclease III [Methanothermobacter thermautotrophicus str. Delta H], gi...
gi|7437101 - pir||B69202 endonuclease III - Methanobacterium thermoautotrophicum (strain Delta H)
9.0E-44 [49..275] [13..223]

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Predicted Domain #1
Region A:
Residues: [1-296]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLKREYDEL IKADAVKEIA KELGSRPLEV ALPEKYIARH EEKFNMACEH ILEKDPSLFP  60
   61 ILKNNEFTLY LKETQVPNTL EDYFIRLAST ILSQQISGQA AESIKARVVS LYGGAFPDYK 120
  121 ILFEDFKDPA KCAEIAKCGL SKRKMIYLES LAVYFTEKYK DIEKLFGQKD NDEEVIESLV 180
  181 TNVKGIGPWS AKMFLISGLK RMDVFAPEDL GIARGFSKYL SDKPELEKEL MRERKVVKKS 240
  241 KIKHKKYNWK IYDDDIMEKC SETFSPYRSV FMFILWRLAS TNTDAMMKAE ENFVKS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 63.28043
Match: 1dizA_
Description: 3-Methyladenine DNA glycosylase II (gene alkA or aidA)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle