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View Structure Prediction Details

Protein: BOI2
Organism: Saccharomyces cerevisiae
Length: 1040 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BOI2.

Description E-value Query
Range
Subject
Range
gi|550095 - gi|550095|dbj|BAA07427.1| Boi2p [Saccharomyces cerevisiae]
692.0 [0..1] [1040..1]
gi|171543839, gi... - gi|62089589|gb|AAH92217.1| Fyn protein [Mus musculus], gi|21594599|gb|AAH32149.1| Fyn protein [Mus m...
371.0 [0..6] [300..46]
gi|9247171 - gi|9247171|gb|AAB33113.2| tyrosine kinase p59fyn(T) [Homo sapiens]
370.0 [0..6] [300..46]
gi|73973788 - gi|73973788|ref|XP_868506.1| PREDICTED: similar to protein-tyrosine kinase fyn isoform 3 [Canis fami...
369.0 [0..6] [300..46]
gi|76625643 - gi|76625643|ref|XP_882042.1| PREDICTED: similar to protein-tyrosine kinase fyn isoform b isoform 15 ...
369.0 [0..6] [300..46]

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Predicted Domain #1
Region A:
Residues: [1-108]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNDREVPTL SQLNTTVSRD KDVSDTLSPD FDSKGSATGR DGGNFPMYIA INEYFKRMED  60
   61 ELDMKPGDKI KVITDDEEYK DGWYFGRNLR TNEEGLYPVV FTQKITVE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 79.522879
Match: 2ptkA
Description: CHICKEN SRC TYROSINE KINASE
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [109-208]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KAPTLMRAKS TKRIYSPLTN EDPLLSSTFI SENDSNSELP TPQPIETAAS ISRTANGKIE  60
   61 RNLSLKNTMS DIDNALLEFK DDSIGPPDRF INSGRDEEHS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 79.522879
Match: 2ptkA
Description: CHICKEN SRC TYROSINE KINASE
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [209-292]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ITHETILSAT DGLDVVESNS KPTTSSSTGF LNGDLENQAT LINGIDTTKL NPVEAEFWSP  60
   61 EEITAYFIME GYDVQSASRF QKHK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 79.522879
Match: 2ptkA
Description: CHICKEN SRC TYROSINE KINASE
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [293-381]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISGKILLELE LVHLKELDIN SFGTRFEIFK EIEKIKEAIR TNGRSLNRAS KTNNANIYNQ  60
   61 LMPPANVDQR ASYRGHVRKT SQSLEDLPS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.681 a.29.10 Description not found.
View Download 0.666 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.594 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.588 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.565 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.563 a.24.28 Description not found.
View Download 0.497 a.24.13 Domain of the SRP/SRP receptor G-proteins

Predicted Domain #5
Region A:
Residues: [382-675]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QQNFIPTPRN TRNSSASKHR PKSLVFDSQE ANANIAPDVQ IPQVVEEMAG NENLFVSPRR  60
   61 APKPPSYPSP AQPPKSPLLN NTRTSPSPAQ LYSWQSPTLS FSGPKRTSYI DQYSSSDSNF 120
  121 NSRSALPKNN QGGGKALSPI PSPTRNSVRN EDSEGKLTSS SKRNSVPYYG YAPESSSDRK 180
  181 SSCSSHEEEQ FQETMNTFER PTSSIYADGS TIASISNDKL AHEKEGKKKP TRHSSSLSSK 240
  241 SKSDSRRNSS LKRSSSASRT SSFKKSSFML SPFRQQFTDN AARSSSPEEN PITS

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 14.79
Match:
Description: No description for 1m2vB was found.

Predicted Domain #6
Region A:
Residues: [676-765]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSEKNSSPI VDKKSSKKSR SKRRSVSAKE AEIFTETVKD DKNKRSASEA IKGETLKGKS  60
   61 LRQMTARPVA KKKQTSAFIE GLRSISVKEA 

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 9.79
Match:
Description: No description for 1ei3A was found.

Predicted Domain #7
Region A:
Residues: [766-963]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKDADFSGWM SKKGSGAMST WKTRFFTLHG TRLSYFSSTT DTRERGLIDI TAHRVVPAKE  60
   61 DDKLVSLYAA STGKGRYCFK LLPPQPGSKK GLTFTQPRTH YFAVDNKEEM RGWMAALIKT 120
  121 TIDIDTSVPI ISSYTTPTVS LSKAQEMLAE AREETKLREQ QMLENEEDED QFLWDQQQLQ 180
  181 QQQHDNNQGQ ADRTISAS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 63.29073
Match: 1fhwA
Description: Grp1
Matching Structure (courtesy of the PDB):

Predicted Domain #8
Region A:
Residues: [964-1040]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TQRTSDEDNT ISTPNLSSAN NTTIGSNGFS SPFLLASGLL SPGVARNSSM RGTEKKGKFS  60
   61 TEEDYFGDNS KHKTDKI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.462 a.28.1 ACP-like
View Download 0.447 a.77.1 DEATH domain
View Download 0.410 a.4.5 "Winged helix" DNA-binding domain
View Download 0.389 a.4.1 Homeodomain-like
View Download 0.367 d.58.1 4Fe-4S ferredoxins
View Download 0.367 d.58.1 4Fe-4S ferredoxins
View Download 0.359 a.28.1 ACP-like
View Download 0.355 a.28.1 ACP-like
View Download 0.345 a.77.1 DEATH domain
View Download 0.321 a.64.2 Bacteriocin AS-48


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle