YRC Public Data Repository - Protein Structure Prediction

Protein:	PRS2
Organism:	Saccharomyces cerevisiae
Length:	318 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRS2.

Description	E-value	Query Range	Subject Range
PRPS1_MOUSE - Ribose-phosphate pyrophosphokinase 1 OS=Mus musculus GN=Prps1 PE=1 SV=3	2.0E-99	[3..318]	[1..318]
PRPS1 - phosphoribosyl pyrophosphate synthetase 1 gi\|208967042, gi... - gi\|208967042\|dbj\|BAG73535.1\| phosphoribosyl pyrophosphate synthetase 1-like 1 [synthetic construct],... ENSCJAT00000043257 - null gi\|114689771, gi... - gi\|114689771\|ref\|XP_001144504.1\| PREDICTED: hypothetical protein isoform 2 [Pan troglodytes], gi\|114... PRPS1_PONAB - Ribose-phosphate pyrophosphokinase 1 OS=Pongo abelii GN=PRPS1 PE=2 SV=1 tr\|M3WGN3\|M3WGN3... - Phosphoribosyl pyrophosphate synthetase 1 OS=Felis catus GN=PRPS1 PE=3 SV=1 PRPS1_PONPY - Ribose-phosphate pyrophosphokinase I - Pongo pygmaeus (Orangutan) gi\|109131827 - gi\|109131827\|ref\|XP_001095604.1\| PREDICTED: similar to Ribose-phosphate pyrophosphokinase I (Phospho... PRPS1_MOUSE - Ribose-phosphate pyrophosphokinase 1 OS=Mus musculus GN=Prps1 PE=1 SV=4 PRPS1_BOVIN - Ribose-phosphate pyrophosphokinase 1 OS=Bos taurus GN=PRPS1 PE=2 SV=3 gi\|74008042 - gi\|74008042\|ref\|XP_850853.1\| PREDICTED: similar to Ribose-phosphate pyrophosphokinase I (Phosphoribo... PRPS1_RAT - Ribose-phosphate pyrophosphokinase 1 OS=Rattus norvegicus GN=Prps1 PE=1 SV=2	2.0E-99	[3..318]	[1..318]
tr\|G3I9Z3\|G3I9Z3... - Ribose-phosphate pyrophosphokinase 2 OS=Cricetulus griseus GN=I79_020407 PE=3 SV=1 PRPS2_RAT - Ribose-phosphate pyrophosphokinase 2 OS=Rattus norvegicus GN=Prps2 PE=1 SV=3	2.0E-98	[3..318]	[1..318]
gi\|221321379 - gi\|221321379\|ref\|ZP_03602673.1\| ribose-phosphate pyrophosphokinase [Bacillus subtilis subsp. subtili... KPRS_BACSU - Ribose-phosphate pyrophosphokinase OS=Bacillus subtilis GN=prs PE=1 SV=1 KPRS_BACSU - Ribose-phosphate pyrophosphokinase OS=Bacillus subtilis (strain 168) GN=prs PE=1 SV=1 gi\|221312183 - gi\|221312183\|ref\|ZP_03593988.1\| ribose-phosphate pyrophosphokinase [Bacillus subtilis subsp. subtili... gi\|221317116 - gi\|221317116\|ref\|ZP_03598410.1\| ribose-phosphate pyrophosphokinase [Bacillus subtilis subsp. subtili...	2.0E-97	[3..313]	[7..316]
gi\|3608149, gi\|1... - gi\|633140\|emb\|CAA58717.1\| phosphoribosyl diphosphate synthetase; ribose-phosphate pyrophosphokinase ...	7.0E-97	[5..313]	[41..351]
KPRS1_SPIOL - Ribose-phosphate pyrophosphokinase 1 OS=Spinacia oleracea GN=PRS1 PE=2 SV=1	2.0E-96	[2..313]	[22..335]

Back

Predicted Domain #1

Region A:
Residues: [1-149]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTNSIKLLA GNSHPGLAEL ISQRLGVPLS KVGVYQYSNK ETSVTIGESI RDEDVYIIQT  60
   61 GYGEHEINDF LMELLILIHA CKTASVRRIT AVIPNFPYAR QDKKDKSRAP ITAKLIANLL 120
  121 ETAGCDHVIT MDLHASQIQG FFHIPVDNL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [293-318]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPTIAEAIRR LHNGESVSYL FTHAPV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	793.383689
Match:	1dkrA_
Description:	Phosphoribosylpyrophosphate synthetase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [150-292]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YGEPSVLNYI RTKTDFNNAI LVSPDAGGAK RVASLADKLD MNFALIHKER QKANEVSRML  60
   61 LVGDVAGKSC LLIDDMADTC GTLVKACDTL MDHGAKEVIA IVTHGIFSGS AREKLINSRL 120
  121 SRIVCTNTVP VDLDLDIVDQ VDI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	793.383689
Match:	1dkrA_
Description:	Phosphoribosylpyrophosphate synthetase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits