YRC Public Data Repository - Protein Structure Prediction

Protein:	RSM18
Organism:	Saccharomyces cerevisiae
Length:	202 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RSM18.

Description	E-value	Query Range	Subject Range
gi\|7440479 - gi\|7440479\|pir\|\|E71370 probable ribosomal protein S18 (rpsR) - syphilis spirochete RS18_TREPA - 30S ribosomal protein S18 OS=Treponema pallidum GN=rpsR PE=3 SV=1 RS18_TREPS - 30S ribosomal protein S18 OS=Treponema pallidum subsp. pallidum (strain SS14) GN=rpsR PE=3 SV=1 RS18_TREPA - 30S ribosomal protein S18 OS=Treponema pallidum (strain Nichols) GN=rpsR PE=3 SV=1	1.0E-23	[114..202]	[6..93]
mRpS18B-PB, mRpS... - The gene mitochondrial ribosomal protein S18B is referred to in FlyBase by the symbol Dmel\mRpS18B (... gi\|220954374, gi... - gi\|220954374\|gb\|ACL89730.1\| mRpS18B-PA [synthetic construct], gi\|220944418\|gb\|ACL84752.1\| mRpS18B-PA...	7.0E-22	[107..202]	[74..181]
RSM18_SCHPO - 37S ribosomal protein rsm18, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN... rsm18 - mitochondrial ribosomal protein subunit S18	3.0E-20	[105..202]	[58..155]
RS18_STAAN - 30S ribosomal protein S18 OS=Staphylococcus aureus (strain N315) GN=rpsR PE=1 SV=1 RS18_STAAB - 30S ribosomal protein S18 OS=Staphylococcus aureus (strain bovine RF122 / ET3-1) GN=rpsR PE=3 SV=1 RS18_STAAW - 30S ribosomal protein S18 OS=Staphylococcus aureus (strain MW2) GN=rpsR PE=3 SV=1 RS18_STAA2 - 30S ribosomal protein S18 OS=Staphylococcus aureus (strain JH1) GN=rpsR PE=3 SV=1 RS18_STAA9 - 30S ribosomal protein S18 OS=Staphylococcus aureus (strain JH9) GN=rpsR PE=3 SV=1 RS18_STAAM - 30S ribosomal protein S18 OS=Staphylococcus aureus (strain Mu50 / ATCC 700699) GN=rpsR PE=3 SV=1 RS18_STAAT - 30S ribosomal protein S18 OS=Staphylococcus aureus (strain USA300 / TCH1516) GN=rpsR PE=3 SV=1 RS18_STAA8 - 30S ribosomal protein S18 OS=Staphylococcus aureus (strain NCTC 8325) GN=rpsR PE=3 SV=1 RS18_STAA3 - 30S ribosomal protein S18 OS=Staphylococcus aureus (strain USA300) GN=rpsR PE=3 SV=1 gi\|227247384, gi... - gi\|227556113\|ref\|ZP_03986160.1\| 30S ribosomal protein S18 [Staphylococcus aureus subsp. aureus MN8],... gi\|227898142, gi... - gi\|227898142\|ref\|ZP_04015947.1\| 30S ribosomal protein S18 [Staphylococcus aureus subsp. aureus TCH60... gi\|251812469, gi... - gi\|251812469\|ref\|ZP_04826942.1\| 30S ribosomal protein S18 [Staphylococcus aureus subsp. aureus TCH70... gi\|253316532 - gi\|253316532\|ref\|ZP_04839745.1\| 30S ribosomal protein S18 [Staphylococcus aureus subsp. aureus str. ... gi\|253730731, gi... - gi\|253730731\|ref\|ZP_04864896.1\| 30S ribosomal protein S18 [Staphylococcus aureus subsp. aureus USA30... RS18_STAAE - 30S ribosomal protein S18 OS=Staphylococcus aureus (strain Newman) GN=rpsR PE=3 SV=1 gi\|253726910, gi... - gi\|253735110\|ref\|ZP_04869275.1\| 30S ribosomal protein S18 [Staphylococcus aureus subsp. aureus TCH13... gi\|255005162 - gi\|255005162\|ref\|ZP_05143763.2\| 30S ribosomal protein S18 [Staphylococcus aureus subsp. aureus Mu50-... gi\|87126925\|gb\|A... - ribosomal protein S18 [Staphylococcus aureus subsp. aureus USA300], ribosomal protein S18 [Staphyloc... RS18_STAA1 - 30S ribosomal protein S18 OS=Staphylococcus aureus (strain Mu3 / ATCC 700698) GN=rpsR PE=3 SV=1 RS18_STAAR - 30S ribosomal protein S18 OS=Staphylococcus aureus (strain MRSA252) GN=rpsR PE=3 SV=1 RS18_STAAS - 30S ribosomal protein S18 OS=Staphylococcus aureus (strain MSSA476) GN=rpsR PE=3 SV=1 gi\|25507763 - pir\|\|H89802 30S ribosomal protein S18 [imported] - Staphylococcus aureus (strain N315) RS18_STAAC - 30S ribosomal protein S18 OS=Staphylococcus aureus (strain COL) GN=rpsR PE=3 SV=1 gi\|269202015\|ref... - 30S ribosomal protein S18 [Staphylococcus aureus subsp. aureus ED98] gi\|221142675 - gi\|221142675\|ref\|ZP_03567168.1\| 30S ribosomal protein S18 [Staphylococcus aureus subsp. aureus str. ... gi\|221139493 - gi\|221139493\|ref\|ZP_03564292.1\| 30S ribosomal protein S18 [Staphylococcus aureus subsp. aureus str. ...	3.0E-20	[139..202]	[10..73]
RS18_CLOP1 - 30S ribosomal protein S18 OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB... RS18_CLOPS - 30S ribosomal protein S18 OS=Clostridium perfringens (strain SM101 / Type A) GN=rpsR PE=3 SV=1 RS18_CLOPE - 30S ribosomal protein S18 OS=Clostridium perfringens GN=rpsR PE=3 SV=1 gi\|168207913, gi... - gi\|170660796\|gb\|EDT13479.1\| ribosomal protein S18 [Clostridium perfringens E str. JGS1987], gi\|16820... gi\|169298406, gi... - gi\|169343454\|ref\|ZP_02864454.1\| ribosomal protein S18 [Clostridium perfringens C str. JGS1495], gi\|1... gi\|182379953, gi... - gi\|182379953\|gb\|EDT77432.1\| ribosomal protein S18 [Clostridium perfringens NCTC 8239], gi\|168218034\|... RS18_CLOPE - 30S ribosomal protein S18 OS=Clostridium perfringens (strain 13 / Type A) GN=rpsR PE=3 SV=1 gi\|170713723, gi... - gi\|170713723\|gb\|EDT25905.1\| ribosomal protein S18 [Clostridium perfringens CPE str. F4969], gi\|16821... gi\|168211574, gi... - gi\|170710455\|gb\|EDT22637.1\| ribosomal protein S18 [Clostridium perfringens B str. ATCC 3626], gi\|168... gi\|182626399, gi... - gi\|182626399\|ref\|ZP_02954152.1\| ribosomal protein S18 [Clostridium perfringens D str. JGS1721], gi\|1...	3.0E-20	[130..202]	[3..75]
gi\|47019373, gi\|... - gi\|47092171\|ref\|ZP_00229963.1\| ribosomal protein S18 [Listeria monocytogenes str. 4b H7858], gi\|4701... gi\|255519953 - gi\|255519953\|ref\|ZP_05387190.1\| 30S ribosomal protein S18 [Listeria monocytogenes FSL J1-175] gi\|255030368 - gi\|255030368\|ref\|ZP_05302319.1\| 30S ribosomal protein S18 [Listeria monocytogenes LO28] gi\|255025177 - gi\|255025177\|ref\|ZP_05297163.1\| 30S ribosomal protein S18 [Listeria monocytogenes FSL J2-003] RS18_LISMF - 30S ribosomal protein S18 OS=Listeria monocytogenes serotype 4b (strain F2365) GN=rpsR PE=3 SV=1 gi\|255022435 - gi\|255022435\|ref\|ZP_05294421.1\| 30S ribosomal protein S18 [Listeria monocytogenes FSL J1-208] RS18_LISMO - 30S ribosomal protein S18 OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) GN=rp... gi\|255017794 - gi\|255017794\|ref\|ZP_05289920.1\| 30S ribosomal protein S18 [Listeria monocytogenes FSL F2-515] RS18_LISIN - 30S ribosomal protein S18 OS=Listeria innocua serovar 6a (strain CLIP 11262) GN=rpsR PE=3 SV=1 gi\|254992264 - gi\|254992264\|ref\|ZP_05274454.1\| 30S ribosomal protein S18 [Listeria monocytogenes FSL J2-064] gi\|47016459, gi\|... - gi\|47095114\|ref\|ZP_00232726.1\| ribosomal protein S18 [Listeria monocytogenes str. 1/2a F6854], gi\|47... gi\|254879868 - gi\|254879868\|ref\|ZP_05252578.1\| 30S ribosomal protein S18 [Listeria monocytogenes FSL J2-071] gi\|254851788 - gi\|254851788\|ref\|ZP_05241136.1\| 30S ribosomal protein S18 [Listeria monocytogenes FSL R2-503] gi\|254824725 - gi\|254824725\|ref\|ZP_05229726.1\| 30S ribosomal protein S18 [Listeria monocytogenes FSL J1-194] RS18_LISMC - 30S ribosomal protein S18 OS=Listeria monocytogenes serotype 4b (strain Clip81459) GN=rpsR PE=3 SV=1 RS18_LISMC - 30S ribosomal protein S18 OS=Listeria monocytogenes serotype 4b (strain CLIP80459) GN=rpsR PE=3 SV=1 RS18_LISMO - 30S ribosomal protein S18 OS=Listeria monocytogenes GN=rpsR PE=3 SV=1 RS18_LISMH - 30S ribosomal protein S18 OS=Listeria monocytogenes serotype 4a (strain HCC23) GN=rpsR PE=3 SV=1 RS18_LISW6 - 30S ribosomal protein S18 OS=Listeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / SLCC533... gi\|224498256 - gi\|224498256\|ref\|ZP_03666605.1\| 30S ribosomal protein S18 [Listeria monocytogenes Finland 1988] gi\|254899633, gi... - gi\|254899633\|ref\|ZP_05259557.1\| 30S ribosomal protein S18 [Listeria monocytogenes J0161], gi\|1531844... gi\|224503029 - gi\|224503029\|ref\|ZP_03671336.1\| 30S ribosomal protein S18 [Listeria monocytogenes FSL R2-561] gi\|254830661, gi... - gi\|254830661\|ref\|ZP_05235316.1\| 30S ribosomal protein S18 [Listeria monocytogenes 10403S], gi\|153198... gi\|254913164, gi... - gi\|254913164\|ref\|ZP_05263176.1\| 30S ribosomal protein S18 [Listeria monocytogenes J2818], gi\|1531926... gi\|254871893, gi... - gi\|254871893\|ref\|ZP_05244603.1\| 30S ribosomal protein S18 [Listeria monocytogenes FSL N1-017], gi\|15... RS18_LISIN - 30S ribosomal protein S18 OS=Listeria innocua GN=rpsR PE=3 SV=1 gi\|153176214, gi... - gi\|254827477\|ref\|ZP_05232164.1\| 30S ribosomal protein S18 [Listeria monocytogenes FSL N3-165], gi\|15... gi\|153181078, gi... - gi\|254937545\|ref\|ZP_05269242.1\| 30S ribosomal protein S18 [Listeria monocytogenes F6900], gi\|1531810... gi\|153200434, gi... - gi\|254930815\|ref\|ZP_05264174.1\| 30S ribosomal protein S18 [Listeria monocytogenes HPB2262], gi\|15320...	4.0E-20	[139..202]	[9..72]
RS18_GEOKA - 30S ribosomal protein S18 OS=Geobacillus kaustophilus (strain HTA426) GN=rpsR PE=3 SV=1 gi\|229497916, gi... - gi\|229497916\|ref\|ZP_04391615.1\| ribosomal protein S18 [Geobacillus sp. Y412MC52], gi\|229331342\|gb\|EE... gi\|196249872, gi... - gi\|196249872\|ref\|ZP_03148568.1\| ribosomal protein S18 [Geobacillus sp. G11MC16], gi\|196210748\|gb\|EDY... gi\|221086943, gi... - gi\|221086943\|ref\|ZP_03556483.1\| ribosomal protein S18 [Geobacillus sp. Y412MC61], gi\|220708996\|gb\|EE... RS18_GEOTN - 30S ribosomal protein S18 OS=Geobacillus thermodenitrificans (strain NG80-2) GN=rpsR PE=3 SV=2 RS18_GEOSE - 30S ribosomal protein S18 OS=Geobacillus stearothermophilus GN=rpsR PE=1 SV=2 RS18_GEOKA - 30S ribosomal protein S18 OS=Geobacillus kaustophilus GN=rpsR PE=3 SV=1	4.0E-20	[138..202]	[8..72]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	4.0E-20	[138..202]	[7..71]
gi\|15836485, gi\|... - gi\|8979326\|dbj\|BAA99160.1\| S18 ribosomal protein [Chlamydophila pneumoniae J138], gi\|15836485\|ref\|NP... gi\|33242320, gi\|... - gi\|33242320\|ref\|NP_877261.1\| 30S ribosomal protein S18 [Chlamydophila pneumoniae TW-183], gi\|3323683... gi\|7189819, gi\|1... - gi\|7189819\|gb\|AAF38692.1\| ribosomal protein S18 [Chlamydophila pneumoniae AR39], gi\|16752078\|ref\|NP_... gi\|4377277, gi\|1... - gi\|4377277\|gb\|AAD19090.1\| S18 Ribosomal Protein [Chlamydophila pneumoniae CWL029], gi\|15618861\|ref\|N... RS18_CHLPN - 30S ribosomal protein S18 OS=Chlamydia pneumoniae GN=rpsR PE=3 SV=1	6.0E-20	[133..202]	[7..76]
RS18_CHLMU - 30S ribosomal protein S18 OS=Chlamydia muridarum GN=rpsR PE=3 SV=2 RS18_CHLMU - 30S ribosomal protein S18 OS=Chlamydia muridarum (strain MoPn / Nigg) GN=rpsR PE=3 SV=2	1.0E-19	[129..202]	[2..75]

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Predicted Domain #1

Region A:
Residues: [1-119]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFYYAFKLHC RVTCWGKKYL GLLYILKYES IINSVTVLTK KARFYTKLRM FKMNATTGIK  60
   61 IQNGMQPIIK GAVSSTFKRA LYNFGIKEKK SVNIEMGRTQ QTKKIDQSLS KKLPKGTIY

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.367	a.27.1	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View	Download	0.381	d.110.1	Profilin (actin-binding protein)
View	Download	0.396	d.110.4	SNARE-like
View	Download	0.469	d.58.20	NAD-binding domain of HMG-CoA reductase
View	Download	0.579	d.58.43	Mechanosensitive channel protein MscS (YggB), C-terminal domain
View	Download	0.579	d.58.43	Mechanosensitive channel protein MscS (YggB), C-terminal domain
View	Download	0.469	d.58.20	NAD-binding domain of HMG-CoA reductase
View	Download	0.396	d.110.4	SNARE-like
View	Download	0.381	d.110.1	Profilin (actin-binding protein)
View	Download	0.367	a.27.1	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View	Download	0.361	c.30.1	PreATP-grasp domain
View	Download	0.355	d.80.1	Tautomerase/MIF
View	Download	0.351	c.52.1	Restriction endonuclease-like
View	Download	0.341	c.95.1	Thiolase-like
View	Download	0.335	a.40.1	Calponin-homology domain, CH-domain
View	Download	0.326	a.24.11	Bacterial GAP domain
View	Download	0.313	d.58.16	Poly(A) polymerase, C-terminal domain
View	Download	0.309	g.44.1	RING/U-box
View	Download	0.291	a.1.1	Globin-like
View	Download	0.269	a.46.1	Methionine synthase domain
View	Download	0.264	f.1.4	Bcl-2 inhibitors of programmed cell death
View	Download	0.262	a.74.1	Cyclin-like
View	Download	0.251	c.59.1	MurD-like peptide ligases, peptide-binding domain
View	Download	0.249	d.58.49	YajQ-like
View	Download	0.220	d.58.22	TRADD, N-terminal domain
View	Download	0.215	c.2.1	NAD(P)-binding Rossmann-fold domains
View	Download	0.214	d.109.1	Actin depolymerizing proteins
View	Download	0.211	c.55.1	Actin-like ATPase domain

Predicted Domain #2

Region A:
Residues: [120-202]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPFDFSMGRI HLDRKYQANK NSNRNDIMKS GANPLEFYAR PRILSRYVTS TGRIQHRDIT  60
   61 GLSAKNQRRL SKAIRRCQAI GLM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.30103
Match:	1fjgR_
Description:	Ribosomal protein S18
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits