YRC Public Data Repository - Protein Structure Prediction

Protein:	PRO3
Organism:	Saccharomyces cerevisiae
Length:	286 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRO3.

Description	E-value	Query Range	Subject Range
gi\|18146299, gi\|... - gi\|18311615\|ref\|NP_563549.1\| pyrroline-5-carboxylate reductase [Clostridium perfringens str. 13], gi... gi\|110674424, gi... - gi\|110799777\|ref\|YP_697323.1\| pyrroline-5-carboxylate reductase [Clostridium perfringens ATCC 13124]... gi\|170710442, gi... - gi\|170710442\|gb\|EDT22624.1\| pyrroline-5-carboxylate reductase [Clostridium perfringens B str. ATCC 3...	2.0E-59	[1..271]	[1..256]
gi\|16799491 - gi\|16799491\|ref\|NP_469759.1\| pyrroline-5-carboxylate reductase [Listeria innocua Clip11262] gi\|25284806, gi\|... - pir\|\|AG1484 1-pyrroline-5-carboxylate reductase (ProC) homolog lin0414 [imported] - Listeria innocua...	2.0E-57	[3..281]	[2..266]
gi\|199603142, gi... - gi\|200390697\|ref\|ZP_03217308.1\| pyrroline-5-carboxylate reductase [Salmonella enterica subsp. enteri... gi\|167992229, gi... - gi\|205329497\|gb\|EDZ16261.1\| pyrroline-5-carboxylate reductase [Salmonella enterica subsp. enterica s... gi\|197243447, gi... - gi\|197265192\|ref\|ZP_03165266.1\| pyrroline-5-carboxylate reductase [Salmonella enterica subsp. enteri... gi\|16418889, gi\|... - gi\|16763766\|ref\|NP_459381.1\| pyrroline-5-carboxylate reductase [Salmonella typhimurium LT2], gi\|1641...	3.0E-57	[1..284]	[1..269]
gi\|254830607, gi... - gi\|254830607\|ref\|ZP_05235262.1\| pyrroline-5-carboxylate reductase [Listeria monocytogenes 10403S], g... gi\|255030311 - gi\|255030311\|ref\|ZP_05302262.1\| pyrroline-5-carboxylate reductase [Listeria monocytogenes LO28] gi\|153173206, gi... - gi\|254828971\|ref\|ZP_05233658.1\| pyrroline-5-carboxylate reductase [Listeria monocytogenes FSL N3-165... gi\|25284805, gi\|... - pir\|\|AE1124 1-pyrroline-5-carboxylate reductase (ProC) homolog lmo0396 [imported] - Listeria monocyt... gi\|16802441 - gi\|16802441\|ref\|NP_463926.1\| pyrroline-5-carboxylate reductase [Listeria monocytogenes EGD-e] gi\|224502310 - gi\|224502310\|ref\|ZP_03670617.1\| pyrroline-5-carboxylate reductase [Listeria monocytogenes FSL R2-561... gi\|224500018 - gi\|224500018\|ref\|ZP_03668367.1\| pyrroline-5-carboxylate reductase [Listeria monocytogenes Finland 19... gi\|255025378 - gi\|255025378\|ref\|ZP_05297364.1\| pyrroline-5-carboxylate reductase [Listeria monocytogenes FSL J2-003...	4.0E-57	[4..281]	[3..266]
PYCR1 - pyrroline-5-carboxylate reductase 1 P5CR1_PONAB - Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Pongo abelii GN=PYCR1 PE=2 SV=1 P5CR1_PONPY - Pyrroline-5-carboxylate reductase 1 - Pongo pygmaeus (Orangutan)	4.0E-57	[3..281]	[1..268]
P5CR1_MOUSE - Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Mus musculus GN=Pycr1 PE=1 SV=1	8.0E-57	[3..281]	[1..268]
gi\|16759364 - gi\|16759364\|ref\|NP_454981.1\| pyrroline-5-carboxylate reductase [Salmonella enterica subsp. enterica ... gi\|214002273 - gi\|214002273\|ref\|ZP_03413008.1\| pyrroline-5-carboxylate reductase [Salmonella enterica subsp. enteri... gi\|16501655, gi\|... - gi\|25284804\|pir\|\|AI0549 pyrroline-5-carboxylate reductase [imported] - Salmonella enterica subsp. en... gi\|29142864, gi\|... - gi\|29142864\|ref\|NP_806206.1\| pyrroline-5-carboxylate reductase [Salmonella enterica subsp. enterica ... gi\|213421027 - gi\|213421027\|ref\|ZP_03354093.1\| pyrroline-5-carboxylate reductase [Salmonella enterica subsp. enteri... gi\|213427797 - gi\|213427797\|ref\|ZP_03360547.1\| pyrroline-5-carboxylate reductase [Salmonella enterica subsp. enteri... gi\|213852997 - gi\|213852997\|ref\|ZP_03382529.1\| pyrroline-5-carboxylate reductase [Salmonella enterica subsp. enteri...	9.0E-57	[1..284]	[1..269]
gi\|218693847, gi... - gi\|218693847\|ref\|YP_002401514.1\| pyrroline-5-carboxylate reductase [Escherichia coli 55989], gi\|2183... gi\|75194606, gi\|... - gi\|75194606\|ref\|ZP_00704676.1\| COG0345: Pyrroline-5-carboxylate reductase [Escherichia coli HS], gi\|... gi\|75209943, gi\|... - gi\|75209943\|ref\|ZP_00710132.1\| COG0345: Pyrroline-5-carboxylate reductase [Escherichia coli B171], g... gi\|75230112, gi\|... - gi\|75230112\|ref\|ZP_00716616.1\| COG0345: Pyrroline-5-carboxylate reductase [Escherichia coli B7A], gi... gi\|193068622, gi... - gi\|75237232\|ref\|ZP_00721279.1\| COG0345: Pyrroline-5-carboxylate reductase [Escherichia coli E110019]... gi\|193065161, gi... - gi\|75256759\|ref\|ZP_00728364.1\| COG0345: Pyrroline-5-carboxylate reductase [Escherichia coli E22], gi... gi\|169887808, gi... - gi\|170079973\|ref\|YP_001729293.1\| pyrroline-5-carboxylate reductase, NAD(P)-binding [Escherichia coli... gi\|188491604, gi... - gi\|75512447\|ref\|ZP_00734986.1\| COG0345: Pyrroline-5-carboxylate reductase [Escherichia coli 53638], ... gi\|169756169, gi... - gi\|170021241\|ref\|YP_001726195.1\| pyrroline-5-carboxylate reductase [Escherichia coli ATCC 8739], gi\|... gi\|85674527, gi\|... - gi\|89107257\|ref\|AP_001037.1\| pyrroline-5-carboxylate reductase, NAD(P)-binding [Escherichia coli str... gi\|218552949, gi... - gi\|218552949\|ref\|YP_002385862.1\| pyrroline-5-carboxylate reductase [Escherichia coli IAI1], gi\|21835... gi\|209910857, gi... - gi\|209917598\|ref\|YP_002291682.1\| pyrroline-5-carboxylate reductase [Escherichia coli SE11], gi\|20991... gi\|24050550, gi\|... - gi\|24111764\|ref\|NP_706274.1\| pyrroline-5-carboxylate reductase [Shigella flexneri 2a str. 301], gi\|2... gi\|30061882, gi\|... - gi\|30061882\|ref\|NP_836053.1\| pyrroline-5-carboxylate reductase [Shigella flexneri 2a str. 2457T], gi... PROC_ECOLI, P5CR... - (P0A9L8) Pyrroline-5-carboxylate reductase (EC 1.5.1.2) (P5CR) (P5C reductase), Pyrroline-5-carboxyl... EG10769 - pyrroline-5-carboxylate reductase, NAD(P)-binding / Pyrroline-5-carboxylate reductase, proline biosy... gi\|83585694, gi\|... - gi\|83585694\|ref\|ZP_00924336.1\| COG0345: Pyrroline-5-carboxylate reductase [Escherichia coli 101-1], ... gi\|157157179, gi... - gi\|75189454\|ref\|ZP_00702721.1\| COG0345: Pyrroline-5-carboxylate reductase [Escherichia coli E24377A]... EG10769 - pyrroline-5-carboxylate reductase, NAD(P)-binding / Pyrroline-5-carboxylate reductase, proline biosy... gi\|124528901, gi... - gi\|124528901\|ref\|ZP_01700086.1\| pyrroline-5-carboxylate reductase [Escherichia coli B], gi\|124500238... gi\|238899676, gi... - gi\|238899676\|ref\|YP_002925472.1\| pyrroline-5-carboxylate reductase, NAD(P)-binding [Escherichia coli... gi\|242376163, gi... - gi\|251783890\|ref\|YP_002998194.1\| hypothetical protein B21_00337 [Escherichia coli BL21], gi\|24237616... gi\|253325676, gi... - gi\|254287255\|ref\|YP_003053003.1\| pyrroline-5-carboxylate reductase [Escherichia coli BL21(DE3)], gi\|... gi\|253972353, gi... - gi\|254160452\|ref\|YP_003043560.1\| pyrroline-5-carboxylate reductase [Escherichia coli B str. REL606],... P5CR_SHIFL - Pyrroline-5-carboxylate reductase OS=Shigella flexneri GN=proC PE=3 SV=1	1.0E-56	[1..284]	[1..269]
gi\|13161407 - gi\|13161407\|dbj\|BAB33038.1\| VuP5CR [Vigna unguiculata]	1.0E-56	[2..282]	[10..274]
gi\|6759462, gi\|2... - gi\|8980281\|emb\|CAB96939.1\| pyrroline-5-carboxylate reductase [Bacillus cereus ATCC 14579], gi\|675946... gi\|229110565, gi... - gi\|229110565\|ref\|ZP_04240133.1\| hypothetical protein bcere0018_28170 [Bacillus cereus Rock1-15], gi\|...	1.0E-56	[1..282]	[1..267]

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Predicted Domain #1

Region A:
Residues: [1-286]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTYTLAILGC GVMGQALLSA IYNAPKAADE TAAAFYPSKI ITCNHDEPSA QQVTDLVETF  60
   61 DESPNGIKVE STYGHNVSAV EEASVVLLGT KPFLAEEVLN GVKSVIGGKL LISLAAGWTI 120
  121 DQLSQYTSTV CRVMTNTPAK YGYGCAVVSY SADVSKEQKP LVNELISQVG KYVELPEKNM 180
  181 DAATALVGSG PAFVLLMLES LMESGLKLGI PLQESKECAM KVLEGTVKMV EKSGAHPSVL 240
  241 KHQVCTPGGT TIAGLCVMEE KGVKSGIING VEEAARVASQ LGQKKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	26.0
Match:	1f12A_
Description:	Short chain L-3-hydroxyacyl CoA dehydrogenase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits