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View Structure Prediction Details

Protein: SEC3
Organism: Saccharomyces cerevisiae
Length: 1336 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SEC3.

Description E-value Query
Range
Subject
Range
SEC3_YEAST - Exocyst complex component SEC3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SEC3 PE=1...
SEC3 - Subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, Exo84p) which me...
0.0 [1..1336] [1..1336]
gi|179508, gi|10... - sp|P12883|MYH7_HUMAN Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta), gi|4557773|ref|NP...
2.0E-84 [1..801] [1108..1926]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
4.0E-84 [1..801] [324..1142]
MYH7_MOUSE - Myosin-7 OS=Mus musculus GN=Myh7 PE=1 SV=1
5.0E-84 [1..801] [1108..1926]
MYH7_RAT - Myosin-7 OS=Rattus norvegicus GN=Myh7 PE=1 SV=2
1.0E-83 [1..801] [1108..1926]
MYH7_MESAU - Myosin-7 OS=Mesocricetus auratus GN=MYH7 PE=2 SV=2
2.0E-83 [1..801] [1107..1925]
MYH1_PIG - Myosin-1 OS=Sus scrofa GN=MYH1 PE=2 SV=1
4.0E-83 [1..810] [1112..1939]

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Predicted Domain #1
Region A:
Residues: [1-160]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSSKSPFKR KSHSRETSHD ENTSFFHKRT ISGSSAHHSR NVSQGAVPSS APPVSGGNYS  60
   61 HKRNVSRASN SSQTSNFLAE QYERDRKAII NCCFSRPDHK TGEPPNNYIT HVRIIEDSKF 120
  121 PSSRPPPDSK LENKKKRLLI LSAKPNNAKL IQIHKARENS 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [161-274]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGSFQIGRTW QLTELVRVEK DLEISEGFIL TMSKKYYWET NSAKERTVFI KSLITLYIQT  60
   61 FEGHVPELVN WDLSLFYLDE RSYQRAVITN RPGSVSPIKS PTSNFTTNTT QSVG

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [308-340]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSLNKAPYS SNSTLNEVNK RYELEQQQQQ EEA

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.32
Match: 1lu7A
Description: No description for 1lu7A was found.

Predicted Domain #3
Region A:
Residues: [275-307]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVPFSAPTER TRRSETESVN PVSTPASVEY HAG

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [341-382]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELRRLEEQKR LQLQKENEMK RLEEERRIKQ EERKRQMELE HQ

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.32
Match: 1lu7A
Description: No description for 1lu7A was found.

Predicted Domain #4
Region A:
Residues: [383-777]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RQLEEEERKR QMELEAKKQM ELKRQRQFEE EQRLKKEREL LEIQRKQREQ ETAERLKKEE  60
   61 QEALAKKEEE EKSKRNKVDN ESYTQEINGK VDNLLEDLNA VLAEETETTP TMQNGTYVPE 120
  121 RSTARAHDQL KKPLNIAKVE SLGGSDLNDS ISLSDEIAGL NTSNLSGEDQ DEKNDLSFEK 180
  181 GDEVRYSNNF EGEAPHVYHE VSIIQEEAPA VSQKLILPEE NNESEALIES KEEIKTMENI 240
  241 DDEVLLEILT DINWSIEDDA DSMIERIDLR LAETEYLFNQ NLLSLQKIGP NIRPYEDKVN 300
  301 DECHRIIPTL SLFLMEMSNF SNDIENVESQ DNGLQVESAN KKLLWNTLDE LLKTVSLDEI 360
  361 SLNQLLECPI REKNLPWMEN QLNLLLKAFQ AIGSD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.09691
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [778-968]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNEVEYNLRE ISGLKQRLQF YEKVTKIFLN RIVEEMQKKF SNIRGQDISH DQMIRILTTL  60
   61 LIFSPLILFC KEISQKSYQA IVENWNVSIQ PVYMELWTKK ISQLQGIDTN DEKMNELSLS 120
  121 QLLNEWDTFR KERKTNDINP VFKNSFSLLT ECLQTMRQEC IVYQNFVEVF FHISSKHNFE 180
  181 EYIKHFNDPD A

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [969-1336]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPILLDTVKV MQSDREAAVI ETQLVSRIFQ PIVTRLSSYF VELVKAEPTV APALTFYLEN  60
   61 EIKSLESSNH EFLLSAVTRM YTQIKQVWSD NVEEQVLHFE RISNATTNGE ILPGILDLPV 120
  121 GLKNSEDLFQ FAKRSMDIKD TDEGYESIEL MNSSFRKLSI AATRSITHKE VNSSINPNLS 180
  181 DTAALNNDYM ETISLLVNSN WLTEMLSMLN FNKDGIFDTS LQNVKKVFDV EKESYASFLL 240
  241 RDTMPKLTAF VYGVSNIIEN TNNVNMTNPS RWAAYSRQNL ENILLAYTSH EIETLVKRLH 300
  301 THMVNDFGYH QENAINNVLC DKLWSCIQGQ TVSLYLKLYT VIDKHYRGTN IRFTKNDIIS 360
  361 AFEEYKNA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle