YRC Public Data Repository - Protein Structure Prediction

Protein:	YEL023C
Organism:	Saccharomyces cerevisiae
Length:	682 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YEL023C.

Description	E-value	Query Range	Subject Range
gi\|190405541 - gi\|190405541\|gb\|EDV08808.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a] YEL023C - Putative protein of unknown function; expression is increased greatly during sporulation; YEL023C is... YEC3_YEAST - Uncharacterized protein YEL023C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YEL023C ...	0.0	[1..682]	[1..682]
gi\|218772206, gi... - gi\|218891980\|ref\|YP_002440847.1\| hypothetical protein PLES_32581 [Pseudomonas aeruginosa LESB58], gi... gi\|11349412 - pir\|\|D83387 hypothetical protein PA2063 [imported] - Pseudomonas aeruginosa (strain PAO1) gi\|9948072, gi\|1... - gi\|9948072\|gb\|AAG05451.1\|AE004633_2 hypothetical protein PA2063 [Pseudomonas aeruginosa PAO1], gi\|15... gi\|194551481, gi... - gi\|84327581\|ref\|ZP_00975599.1\| COG3673: Uncharacterized conserved protein [Pseudomonas aeruginosa 21... gi\|107101490 - gi\|107101490\|ref\|ZP_01365408.1\| hypothetical protein PaerPA_01002533 [Pseudomonas aeruginosa PACS2]	1.0E-94	[32..250]	[23..240]
gi\|221235715, gi... - gi\|221235715\|ref\|YP_002518152.1\| hypothetical protein CCNA_02779 [Caulobacter crescentus NA1000], gi... gi\|25397463 - pir\|\|A87583 peptidoglycan binding domain protein [imported] - Caulobacter crescentus gi\|16126929, gi\|... - gi\|16126929\|ref\|NP_421493.1\| peptidoglycan binding domain-containing protein [Caulobacter crescentus...	9.0E-86	[30..248]	[29..262]

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Predicted Domain #1

Region A:
Residues: [1-174]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSFNYIHGK YKKNGTGGDR SINPSSHSSS GKNIILCFDG TRENFGPQPF TNILKLYNLL  60
   61 ENGDSSEQIC YYQPGIGSVG FDAVVDVRRR LTISHLQNLL DSMFAFSLDN HICSAYLFLM 120
  121 KYFEPGDRIY MFGFSRGAFI ARVLAGMIER VGLLSKGLEE MVKMAWQIYE KWEY

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	7.24
Match:	1cudA
Description:	Cutinase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [175-682]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSQPNELQYT STLAEEFKKT FSRDYEVKIH FQGLFDSVNS VGILRDRLFP CTQRSNIVEH  60
   61 VRHCVSLDER RGKFKQLCFT PMPYIPKLFS LTYCNHITDQ CSPVPTSNAL MRDLTPENPL 120
  121 IKYTLKSGAH SISNPSPLIP DNPGRLLSSK SEETTELLLD LNSFLEGNSY ARDTECSTRG 180
  181 IEAIFQLQSI QGSGTSSRMT MTPDLIEKWF PGDHSDVGGG WAPDCETEEN LSNLTLRWIL 240
  241 AEAIKFGVKF KPGAIHDFAT KHTSIGSLFA DTHDYLSFNS PKKCSLLGVS DNEDGAREDK 300
  301 SGRNERMEDC LKNIKETRLS LKDEKEKVKD AFTLKCGHAN KFMRLVWWVL ELLPIGIRME 360
  361 NKEGKWQNFH TPNLGRSRYV PEYVSLHWSV YWRIKFDRRY RPDNMPEYVR QLFQDLEGID 420
  421 LKSNKVSNKY DKQDNSNGSE INGGFFDNEE GQELHMGQKA SYFATTYNSR LFDSKYSQLK 480
  481 KKFMDWDSNS WTDIPDDLKI YLQQDESL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [270-371]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HITDQCSPVP TSNALMRDLT PENPLIKYTL KSGAHSISNP SPLIPDNPGR LLSSKSEETT  60
   61 ELLLDLNSFL EGNSYARDTE CSTRGIEAIF QLQSIQGSGT SS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [372-430]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RMTMTPDLIE KWFPGDHSDV GGGWAPDCET EENLSNLTLR WILAEAIKFG VKFKPGAIH

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [431-593]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DFATKHTSIG SLFADTHDYL SFNSPKKCSL LGVSDNEDGA REDKSGRNER MEDCLKNIKE  60
   61 TRLSLKDEKE KVKDAFTLKC GHANKFMRLV WWVLELLPIG IRMENKEGKW QNFHTPNLGR 120
  121 SRYVPEYVSL HWSVYWRIKF DRRYRPDNMP EYVRQLFQDL EGI

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6

Region A:
Residues: [594-682]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLKSNKVSNK YDKQDNSNGS EINGGFFDNE EGQELHMGQK ASYFATTYNS RLFDSKYSQL  60
   61 KKKFMDWDSN SWTDIPDDLK IYLQQDESL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits