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View Structure Prediction Details

Protein: GCN4
Organism: Saccharomyces cerevisiae
Length: 281 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GCN4.

Description E-value Query
Range
Subject
Range
GCN4_YEAST - General control protein GCN4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GCN4 PE=1 S...
GCN4 - Basic leucine zipper (bZIP) transcriptional activator of amino acid biosynthetic genes in response t...
4.0E-46 [1..281] [1..281]
ATF4_RAT - Cyclic AMP-dependent transcription factor ATF-4 OS=Rattus norvegicus GN=Atf4 PE=1 SV=1
3.0E-26 [46..279] [119..328]
gi|567226 - gi|567226|gb|AAA53043.1| mATF4
4.0E-25 [46..279] [117..327]
gi|1110452 - gi|1110452|dbj|BAA03562.1| hCREM 1alpha protein [Homo sapiens]
5.0E-24 [40..281] [10..246]

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Predicted Domain #1
Region A:
Residues: [1-199]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEYQPSLFA LNPMGFSPLD GSKSTNENVS ASTSTAKPMV GQLIFDKFIK TEEDPIIKQD  60
   61 TPSNLDFDFA LPQTATAPDA KTVLPIPELD DAVVESFFSS STDSTPMFEY ENLEDNSKEW 120
  121 TSLFDNDIPV TTDDVSLADK AIESTEEVSL VPSNLEVSTT SFLPTPVLED AKLTQTRKVK 180
  181 KPNSVVKKSH HVGKDDESR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [200-281]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDHLGVVAYN RKQRSIPLSP IVPESSDPAA LKRARNTEAA RRSRARKLQR MKQLEDKVEE  60
   61 LLSKNYHLEN EVARLKKLVG ER

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 256.9794
Match: 2dgcA_
Description: GCN4
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [220-281]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IVPESSDPAA LKRARNTEAA RRSRARKLQR MKQLEDKVEE LLSKNYHLEN EVARLKKLVG  60
   61 ER

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.30103
Match: 2dgcA
Description: GCN4
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle