YRC Public Data Repository - Protein Structure Prediction

Protein:	YDR506C
Organism:	Saccharomyces cerevisiae
Length:	608 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YDR506C.

Description	E-value	Query Range	Subject Range
YDR506C - Possible membrane-localized protein GMC1_YEAST - Putative multicopper oxidase GMC1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GMC1 P...	0.0	[1..608]	[1..608]
gi\|2264400 - gi\|2264400\|gb\|AAB63445.1\| phenoloxidase [basidiomycete CECT 20197]	0.0	[6..579]	[6..523]
gi\|10801036 - gi\|10801036\|emb\|CAC13040.1\| laccase [Funalia trogii]	0.0	[10..579]	[7..516]
gi\|16041065 - gi\|16041065\|dbj\|BAB69775.1\| laccase [Pycnoporus coccineus]	0.0	[10..579]	[7..517]
gi\|10179427, gi\|... - gi\|6466835\|gb\|AAF13052.1\|AF170093_1 laccase [Pycnoporus cinnabarinus], gi\|10179427\|gb\|AAG13724.1\|AF1...	0.0	[11..579]	[7..517]
gi\|58324 - gi\|58324\|emb\|CAA78144.1\| laccase [basidiomycete PM1]	0.0	[10..579]	[7..516]
gi\|6318611, gi\|2... - gi\|6318611\|gb\|AAF06967.1\|AF162785_1 polyphenoloxidase [basidiomycete C30], gi\|20086991\|gb\|AAM10738.1...	0.0	[10..579]	[7..516]
LAC4_TRAVE - Laccase-4 OS=Trametes versicolor GN=LCC4 PE=3 SV=1	0.0	[8..579]	[6..519]

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Predicted Domain #1

Region A:
Residues: [1-365]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVILLKPVQ LPMLLLILLK FIMAAKEGKI HVLEFNASSE YTLDKRRVIS INGYSATFGP  60
   61 EIRVKSGDTL NLKLTNWICS EEEASKDSDV WKDYCSTALH FHGVVPLANE FDGIPGLTQP 120
  121 TIGYGESYWY NFTIDQSTCG TFWYHSHSSV QYGDGMRGVL IVECDDYDNH VANTINSVRD 180
  181 IETLDDGVVT MKKDKHTKEL TDYEVQERII TLSDWYTNWN LDILNDKVLS STGGTDPKFD 240
  241 GSLINGKSSD GETIKIGFNT EYLLLRIVNS GMSGTQVFHL DGFQLIVLEA DGIMIKPFIV 300
  301 QTINLAVGQR YTILVKLKSD TSFIRMINGC NKMMGYITKQ WWFYKEGAHL DLPKNPNDVS 360
  361 IEHLP

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [559-608]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTAVLSYPTK EPDPNTVVHT AALEQNKSKV IAVYILIMCA VDAIFYWLLM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	392.0
Match:	1hfuA_
Description:	Laccase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [366-558]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GFTKAELYRD IEPTQEENKK LRTKADPVAV FEFDYAYYKD ESTKQKYGTG MYKVNERTFS  60
   61 EYVKDPVRFG FNETYDIVIN SLDHMRHPWH MHGHHFQIIS LGNKGDGPFH KDVQEGKAWS 120
  121 RYQNDLRHLA RTGKAPMVRD SINIAGNSYA VLRINTEMPG KWLLHCHVEW HMMKGLGIVF 180
  181 EVPTTTEDST KQA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	392.0
Match:	1hfuA_
Description:	Laccase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits