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View Structure Prediction Details

Protein: PRP3
Organism: Saccharomyces cerevisiae
Length: 469 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRP3.

Description E-value Query
Range
Subject
Range
PRP3 - Splicing factor, component of the U4/U6-U5 snRNP complex
gi|207346241 - gi|207346241|gb|EDZ72795.1| YDR473Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190404604 - gi|190404604|gb|EDV07871.1| snRNP from U4/U6 and U5 snRNPs [Saccharomyces cerevisiae RM11-1a]
PRP3_YEAST - U4/U6 small nuclear ribonucleoprotein PRP3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) ...
0.0 [1..469] [1..469]
CG7757-PA - This gene is referred to in FlyBase by the symbol Dmel\CG7757 (CG7757, FBgn0036915). It is a protein...
0.0 [21..469] [167..587]
prp3 - U4 /U6 x U5 tri-snRNP complex subunit Prp3
PRP3_SCHPO - U4/U5/U6 small nuclear ribonucleoprotein prp3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843)...
0.0 [37..469] [131..537]
CE03498 - status:Confirmed UniProt:Q21486 protein_id:CAA88957.1
0.0 [38..466] [207..604]
tr|G1T1X4|G1T1X4... - pep:novel chromosome:oryCun2:13:41703230:41729123:-1 gene:ENSOCUG00000011760 transcript:ENSOCUT00000...
gi|149751209 - gi|149751209|ref|XP_001489457.1| PREDICTED: similar to U4/U6 small nuclear ribonucleoprotein Prp3 (P...
tr|F2Z4C4|F2Z4C4... - Isoform of Q2KIA6, U4/U6 small nuclear ribonucleoprotein Prp3 OS=Bos taurus GN=PRPF3 PE=4 SV=1
tr|G3H2W0|G3H2W0... - U4/U6 small nuclear ribonucleoprotein Prp3 OS=Cricetulus griseus GN=I79_004563 PE=4 SV=1
CCDS951.1_1 - null
tr|M3WJS5|M3WJS5... - Pre-mRNA processing factor 3 OS=Felis catus GN=PRPF3 PE=4 SV=1
PRPF3 - PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae)
gi|73981301 - gi|73981301|ref|XP_533045.2| PREDICTED: similar to U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-m...
gi|123986789, gi... - gi|123999026|gb|ABM87099.1| PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae) [synthetic con...
gi|114559255 - gi|114559255|ref|XP_001168487.1| PREDICTED: PRP3 pre-mRNA processing factor 3 homolog isoform 2 [Pan...
0.0 [13..467] [248..673]
PRPF3_MOUSE - U4/U6 small nuclear ribonucleoprotein Prp3 OS=Mus musculus GN=Prpf3 PE=1 SV=1
0.0 [13..467] [248..673]
gi|25511671, gi|... - pir||C86406 88.6K hypothetical protein F13K9.16 - Arabidopsis thaliana, gi|22022524|gb|AAM83220.1| ...
0.0 [21..467] [347..780]
gi|28917045, gi|... - gi|32415193|ref|XP_328076.1| hypothetical protein [Neurospora crassa], gi|28917045|gb|EAA26769.1| hy...
gi|85077306 - gi|85077306|ref|XP_956005.1| hypothetical protein NCU01637 [Neurospora crassa OR74A]
0.0 [59..468] [98..483]

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Predicted Domain #1
Region A:
Residues: [1-178]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPRNTYEKG NPKRQNSPYY KPSFLRREET TNDEEKFQGH GLKTELHSAL KSSNLNLIRR  60
   61 TYQTGENPYL SDPHDRGSSS RFNRRYERGL KFYQKGEISK RIAQERTLQK QQEEEELKRK 120
  121 LKQEEDEKDK RKLIESGDLP NLELHEDKFL LDLSKFKIYY DNNHGYEWWD TAYLDEKG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [179-351]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELMEKYDMNG TSPAEEKLAE DIDEVDDDDD DEHPSIRYVA HPLPEKINEA KVSIKAYLTQ  60
   61 HERKRLRRNR RKMAREAREI KIKLGLLPKP EPKVKLSNMM SVFENDQNIT DPTAWEKVVK 120
  121 DQVDLRKRKH LEENERRHED AIKRRKEAVN MNVEKPTVYH CKVFQFKNLQ NPK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [352-469]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IRFKLKMNSK ELSLKGLCLR IRDDGPGIII VVGNEKSCKF YENLVMKRIK WNEDFELHTN  60
   61 TGDIKMDMHN NSISKTWEGY LQDCKFKGWF MKVCNDQDSL LRTLGQFDSE HFYSPVQT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.518 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.459 b.50.1 Acid proteases
View Download 0.453 d.15.1 Ubiquitin-like
View Download 0.422 c.55.3 Ribonuclease H-like
View Download 0.429 d.58.26 GHMP Kinase, C-terminal domain
View Download 0.412 c.30.1 PreATP-grasp domain
View Download 0.396 c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.387 d.13.1 HIT-like
View Download 0.366 c.25.1 Ferredoxin reductase-like, C-terminal NADP-linked domain
View Download 0.365 d.58.39 Glutamyl tRNA-reductase catalytic, N-terminal domain
View Download 0.365 d.58.11 EF-G/eEF-2 domains III and V
View Download 0.362 d.54.1 Enolase N-terminal domain-like
View Download 0.346 d.15.11 Doublecortin (DC)
View Download 0.338 c.25.1 Ferredoxin reductase-like, C-terminal NADP-linked domain
View Download 0.327 d.42.1 POZ domain
View Download 0.296 b.55.1 PH domain-like
View Download 0.286 d.58.2 Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain
View Download 0.283 d.89.1 Origin of replication-binding domain, RBD-like
View Download 0.274 c.97.1 Cytidine deaminase-like
View Download 0.271 c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.261 d.96.1 Tetrahydrobiopterin biosynthesis enzymes-like
View Download 0.250 c.55.7 Methylated DNA-protein cysteine methyltransferase domain
View Download 0.247 d.34.1 DNA-binding domain of Mlu1-box binding protein MBP1
View Download 0.240 d.109.1 Actin depolymerizing proteins
View Download 0.236 c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.234 a.1.1 Globin-like
View Download 0.232 c.25.1 Ferredoxin reductase-like, C-terminal NADP-linked domain
View Download 0.226 c.55.7 Methylated DNA-protein cysteine methyltransferase domain
View Download 0.218 d.15.1 Ubiquitin-like
View Download 0.216 d.58.26 GHMP Kinase, C-terminal domain
View Download 0.210 d.58.3 Protease propeptides/inhibitors


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