YRC Public Data Repository - Protein Structure Prediction

Protein:	UTP6
Organism:	Saccharomyces cerevisiae
Length:	440 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UTP6.

Description	E-value	Query Range	Subject Range
gi\|170992 - gi\|170992\|gb\|AAA34394.1\| open reading frame found c-terminal of ADA2 that was sequenced during the c...	479.0	[0..1]	[440..1]
gi\|50292121, gi\|... - gi\|50292121\|ref\|XP_448493.1\| unnamed protein product [Candida glabrata], gi\|49527805\|emb\|CAG61454.1\|... gi\|49527805 - gi\|49527805\|emb\|CAG61454.1\| unnamed protein product [Candida glabrata]	301.0	[0..6]	[440..7]
gi\|44983987 - gi\|44983987\|gb\|AAS52997.1\| AER317Wp [Ashbya gossypii ATCC 10895] gi\|45190919, gi\|... - gi\|45190919\|ref\|NP_985173.1\| AER317Wp [Ashbya gossypii ATCC 10895], gi\|44983987\|gb\|AAS52997.1\| AER31...	294.0	[0..3]	[440..4]
gi\|49640730 - gi\|49640730\|emb\|CAH01991.1\| KLLA0B01518p [Kluyveromyces lactis] gi\|50303313, gi\|... - gi\|50303313\|ref\|XP_451598.1\| unnamed protein product [Kluyveromyces lactis], gi\|49640730\|emb\|CAH0199...	291.0	[0..6]	[440..7]
gi\|49657834 - gi\|49657834\|emb\|CAG90652.1\| DEHA2G14410p [Debaryomyces hansenii] gi\|49657834, gi\|... - gi\|50427113\|ref\|XP_462164.1\| hypothetical protein DEHA0G15334g [Debaryomyces hansenii CBS767], gi\|49...	188.0	[0..2]	[433..3]
gi\|73992767 - gi\|73992767\|ref\|XP_534481.2\| PREDICTED: similar to U5 snRNP-associated 102 kDa protein [Canis famili...	180.0	[0..1]	[279..652]
gi\|46362551 - gi\|46362551\|gb\|AAH66556.1\| C20orf14 homolog (H. sapiens) [Danio rerio]	178.0	[0..1]	[279..596]
PRP6_RAT - Pre-mRNA-processing factor 6 OS=Rattus norvegicus GN=Prpf6 PE=1 SV=1	177.0	[0..1]	[279..593]
PRP6_MOUSE - Pre-mRNA-processing factor 6 OS=Mus musculus GN=Prpf6 PE=1 SV=1	177.0	[0..1]	[279..593]

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Predicted Domain #1

Region A:
Residues: [1-64]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKTRYYLEQ CIPEMDDLVE KGLFTKNEVS LIMKKRTDFE HRLNSRGSSI NDYIKYINYE  60
   61 SNVN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	13.0
Match:	1fchA
Description:	Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [65-124]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLRAKRCKRI LQVKKTNSLS DWSIQQRIGF IYQRGTNKFP QDLKFWAMYL NYMKARGNQT  60
   61

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	13.0
Match:	1fchA
Description:	Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [125-221]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SYKKIHNIYN QLLKLHPTNV DIWISCAKYE YEVHANFKSC RNIFQNGLRF NPDVPKLWYE  60
   61 YVKFELNFIT KLINRRKVMG LINEREQELD MQNEQKN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	13.0
Match:	1fchA
Description:	Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [222-289]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NQAPDEEKSH LQVPSTGDSM KDKLNELPEA DISVLGNAET NPALRGDIAL TIFDVCMKTL  60
   61 GKHYINKH

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.828	a.60.12	DNA polymerase beta-like, second domain
View	Download	0.828	a.60.12	DNA polymerase beta-like, second domain
View	Download	0.812	a.60.12	DNA polymerase beta-like, second domain
View	Download	0.807	a.60.2	RuvA domain 2-like
View	Download	0.649	a.230.1	Description not found.
View	Download	0.637	a.60.4	DNA repair protein Rad51, N-terminal domain
View	Download	0.555	a.60.2	RuvA domain 2-like
View	Download	0.555	a.60.2	RuvA domain 2-like

Predicted Domain #5

Region A:
Residues: [290-440]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KGYYAISDSK MNIELNKETL NYLFSESLRY IKLFDEFLDL ERDYLINHVL QFWKNDMYDL  60
   61 SLRKDLPELY LKTVMIDITL NIRYMPVEKL DIDQLQLSVK KYFAYISKLD SASVKSLKNE 120
  121 YRSYLQDNYL KKMNAEDDPR YKILDLIISK L

[Run NCBI BLAST on this sequence.]

Detection Method:	ab initio
Confidence:	3.54
Match:
Description:	No description for 1bn6A was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits