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View Structure Prediction Details

Protein: THI74
Organism: Saccharomyces cerevisiae
Length: 370 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for THI74.

Description E-value Query
Range
Subject
Range
WAT1_ARATH - Protein WALLS ARE THIN 1 OS=Arabidopsis thaliana GN=WAT1 PE=1 SV=1
1.0E-35 [57..363] [22..353]
gi|14090211, gi|... - gi|34895316|ref|NP_909001.1| putative nodulin-like protein 5NG4 [Oryza sativa (japonica cultivar-gro...
2.0E-35 [55..368] [17..344]
YMB8_YEAST - Uncharacterized vacuolar membrane protein YML018C OS=Saccharomyces cerevisiae (strain ATCC 204508 / ...
YML018C - Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th...
7.0E-33 [7..348] [10..366]
gi|2598575 - gi|2598575|emb|CAA75575.1| MtN21 [Medicago truncatula]
7.0E-33 [47..367] [11..350]

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Predicted Domain #1
Region A:
Residues: [1-199]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRVGIDVDH MIGVLLLAVV VVFWVGASCL TNELLETNAY NKPFFLTYLN ISSFALYLTP  60
   61 DLWRIIQSRR KSLQERTERT LPIHTQESFS EFLPLLSSTP STSSNLSSIA DTKVKDTMRL 120
  121 SLLFCVLWFV ANLAANAALS YTTVASSTIL SSTSSFFTLF LATSLGIETF STKKLLGLFV 180
  181 SLFGIILIVM QSSKQQDSV

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 2.327902
Match: PF00892
Description: Integral membrane protein DUF6

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [200-370]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SASSFLVGNT LALLGSLGYS VYTTLLKYEI SSKGLRLDIQ MFLGYVGIFT FLLFWPILII  60
   61 LDITHMETFE LPSNFHISFL VMLNCIIIFV SDYFWCKALI LTSPLVVTVA LTFTIPLAMF 120
  121 ADFVWREAFF TPWYIIGVIF IFVSFFLVNH RGESAVEKDC AAVEKGPILD A

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.382 0.250 integral to membrane c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.517 0.001 integral to membrane a.74.1 Cyclin-like
View Download 0.370 0.000 integral to membrane a.29.2 Bromodomain
View Download 0.391 0.000 integral to membrane a.126.1 Serum albumin-like
View Download 0.365 N/A N/A a.126.1 Serum albumin-like
View Download 0.286 N/A N/A c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.275 N/A N/A a.126.1 Serum albumin-like
View Download 0.266 N/A N/A a.167.1 Porin chaperone SurA, peptide-binding domain
View Download 0.265 N/A N/A a.1.1 Globin-like
View Download 0.258 N/A N/A a.126.1 Serum albumin-like
View Download 0.257 N/A N/A b.40.4 Nucleic acid-binding proteins
View Download 0.246 N/A N/A a.26.1 4-helical cytokines
View Download 0.220 N/A N/A a.79.1 Antitermination factor NusB
View Download 0.213 N/A N/A c.3.1 FAD/NAD(P)-binding domain
View Download 0.213 N/A N/A a.1.1 Globin-like
View Download 0.201 N/A N/A c.25.1 Ferredoxin reductase-like, C-terminal NADP-linked domain
View Download 0.201 N/A N/A a.111.1 Acid phosphatase/Vanadium-dependent haloperoxidase
View Download 0.200 N/A N/A c.2.1 NAD(P)-binding Rossmann-fold domains

Predicted Domain #3
Region A:
Residues: [202-370]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSFLVGNTLA LLGSLGYSVY TTLLKYEISS KGLRLDIQMF LGYVGIFTFL LFWPILIILD  60
   61 ITHMETFELP SNFHISFLVM LNCIIIFVSD YFWCKALILT SPLVVTVALT FTIPLAMFAD 120
  121 FVWREAFFTP WYIIGVIFIF VSFFLVNHRG ESAVEKDCAA VEKGPILDA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.517 N/A N/A a.74.1 Cyclin-like
View Download 0.391 N/A N/A a.126.1 Serum albumin-like
View Download 0.382 N/A N/A c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.370 N/A N/A a.29.2 Bromodomain
View Download 0.365 N/A N/A a.126.1 Serum albumin-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle