YRC Public Data Repository - Protein Structure Prediction

Protein:	PPZ2
Organism:	Saccharomyces cerevisiae
Length:	710 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PPZ2.

Description	E-value	Query Range	Subject Range
gi\|311119 - gi\|311119\|gb\|AAA34899.1\| type 1-related protein phosphatase	797.0	[0..1]	[710..1]
gi\|85116346 - gi\|85116346\|ref\|XP_965036.1\| serine/threonine-protein phosphatase PP-Z [Neurospora crassa OR74A] gi\|28926837, gi\|... - gi\|32414591\|ref\|XP_327775.1\| hypothetical protein ( (AF071751) protein phosphatase-Z-like serine/thr...	586.0	[0..154]	[703..3]
gi\|4193369, gi\|4... - gi\|4193369\|gb\|AAD09996.1\| protein phosphatase-Z-like serine/threonine protein phosphatase [Neurospor...	579.0	[0..154]	[703..3]
gi\|67616500 - gi\|67616500\|ref\|XP_667490.1\| hypothetical protein [Cryptosporidium hominis TU502] gi\|54658626 - gi\|54658626\|gb\|EAL37255.1\| hypothetical protein Chro.70303 [Cryptosporidium hominis]	570.0	[0..379]	[696..4]
gi\|7209508 - gi\|7209508\|dbj\|BAA92244.1\| type 1 protein phosphatase-1 [Vicia faba]	570.0	[0..378]	[701..1]
PP1_ORYSJ - Serine/threonine-protein phosphatase PP1 OS=Oryza sativa subsp. japonica GN=Os03g0268000 PE=2 SV=2 PP1_ORYSA - Serine/threonine-protein phosphatase PP1 (EC 3.1.3.16) - Oryza sativa (Rice)	568.0	[0..393]	[701..15]
gi\|2117989, gi\|2... - gi\|220873\|dbj\|BAA14197.1\| protein phosphatase 1, catalytic subunit [Rattus norvegicus], gi\|2117989\|p...	567.0	[0..390]	[705..1]
gi\|7435129, gi\|3... - pir\|\|T09544 phosphoprotein phosphatase (EC 3.1.3.16), catalytic beta chain - alfalfa, gi\|3176072\|emb...	567.0	[0..393]	[694..1]

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Predicted Domain #1

Region A:
Residues: [1-326]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNSGSKQHT KHNSKKDDHD GDRKKTLDLP PLTKSDTTHS LKSSRSLRSL RSKRSEASLA  60
   61 SNVQAQTQPL SRRSSTLGNG NRNHRRSNNA PITPPNNHYL TSHPSSSRRL SSSSRRSSMG 120
  121 NNNNSELPPS MIQMEPKSPI LKNSTSMHST SSFNSYENAL TDDDDDRGDD GGESPSMAKV 180
  181 TRINTSSSAD RGSKRTPLRR HNSLQPEKGV TGFSSTSSKL RRRSDNTLPA SYPLNAEAGG 240
  241 NGSDYFSNRS NSHASSRKSS FGSTGNTAYS TPLHSPALRK MSSRDNDDSG DNVNGRGTSP 300
  301 IPNLNIDKPS PSASSASKRE YLSAYP

[Run NCBI BLAST on this sequence.]

Detection Method:	ab initio
Confidence:	9.95
Match:
Description:	No description for 1i3qA was found.

Predicted Domain #2

Region A:
Residues: [327-389]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TLAHRDSSSS LSPRGKGQRS SSSSSSSQRI YVSPPSPTGD FVHGSCADGD NGSRTNTMVE  60
   61 MKR

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [390-710]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKPVRPVDID EIIQRLLDAG YAAKRTKNVC LKNSEIIQIC HKARELFLAQ PALLELSPSV  60
   61 KIVGDVHGQY ADLLRLFTKC GFPPMANYLF LGDYVDRGKQ SLETILLLLC YKIKYPENFF 120
  121 LLRGNHECAN VTRVYGFYDE CKRRCNIKIW KTFVDTFNTL PLAAIVTGKI FCVHGGLSPV 180
  181 LNSMDEIRHV SRPTDVPDFG LINDLLWSDP TDSSNEWEDN ERGVSFCYNK VAINKFLNKF 240
  241 GFDLVCRAHM VVEDGYEFFN DRSLVTVFSA PNYCGEFDNW GAVMTVSEGL LCSFELLDPL 300
  301 DSTALKQVMK KGRQERKLAN R

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1377.0
Match:	1it6A
Description:	Protein phosphatase-1 (PP-1)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits