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View Structure Prediction Details

Protein: CAD1
Organism: Saccharomyces cerevisiae
Length: 409 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CAD1.

Description E-value Query
Range
Subject
Range
gi|545482 - gi|545482|gb|AAB29937.1| AP-1-like stress-induced transcriptional activator [Saccharomyces cerevisia...
0.0 [1..409] [1..409]
gi|15148924 - gi|15148924|gb|AAK84889.1|AF402608_1 TGA-type basic leucine zipper protein TGA2.1 [Phaseolus vulgari...
3.0E-38 [4..184] [137..319]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
5.0E-38 [4..184] [135..318]
TGA21_TOBAC - TGACG-sequence-specific DNA-binding protein TGA-2.1 OS=Nicotiana tabacum GN=TGA21 PE=1 SV=1
1.0E-37 [3..184] [128..305]
TGA6_ARATH - Transcription factor TGA6 OS=Arabidopsis thaliana GN=TGA6 PE=1 SV=2
1.0E-36 [4..184] [1..183]

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Predicted Domain #1
Region A:
Residues: [1-133]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNILRKGQQ IYLAGDMKKQ MLLNKDGTPK RKVGRPGRKR IDSEAKSRRT AQNRAAQRAF  60
   61 RDRKEAKMKS LQERVELLEQ KDAQNKTTTD FLLCSLKSLL SEITKYRAKN SDDERILAFL 120
  121 DDLQEQQKRE NEK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.54902
Match: 1gd2E_
Description: PAP1
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [134-260]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTSTAVSKAA KELPSPNSDE NMTVNTSIEV QPHTQENEKV MWNIGSWNAP SLTNSWDSPP  60
   61 GNRTGAVTIG DESINGSEMP DFSLDLVSND RQTGLEALDY DIHNYFPQHS ERLTAEKIDT 120
  121 SACQCEI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.395 0.424 response to cadmium ion a.3.1 Cytochrome c
View Download 0.405 0.013 response to cadmium ion d.82.2 Frataxin-like
View Download 0.258 0.008 response to cadmium ion b.89.1 Cyanovirin-N
View Download 0.490 N/A N/A d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.307 N/A N/A d.54.1 Enolase N-terminal domain-like

Predicted Domain #3
Region A:
Residues: [261-326]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DQKYLPYETE DDTLFPSVLP LAVGSQCNNI CNRKCIGTKP CSNKEIKCDL ITSHLLNQKS  60
   61 LASVLP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.591 a.77.1 DEATH domain
View Download 0.490 d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.455 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.405 d.82.2 Frataxin-like
View Download 0.395 a.3.1 Cytochrome c
View Download 0.372 d.58.23 Probable ACP-binding domain of malonyl-CoA ACP transacylase
View Download 0.349 a.64.2 Bacteriocin AS-48
View Download 0.343 a.156.1 S13-like H2TH domain
View Download 0.342 a.4.1 Homeodomain-like
View Download 0.313 a.77.1 DEATH domain
View Download 0.308 a.4.1 Homeodomain-like
View Download 0.307 d.54.1 Enolase N-terminal domain-like
View Download 0.294 d.58.24 CheY-binding domain of CheA
View Download 0.290 a.4.1 Homeodomain-like
View Download 0.283 d.45.1 ClpS-like
View Download 0.256 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.252 d.64.1 eIF1-like
View Download 0.250 a.4.5 "Winged helix" DNA-binding domain
View Download 0.242 d.58.7 RNA-binding domain, RBD
View Download 0.235 a.5.2 UBA-like
View Download 0.233 d.27.1 Ribosomal protein S16
View Download 0.227 a.4.12 TrpR-like
View Download 0.226 a.15.1 TAF(II)230 TBP-binding fragment
View Download 0.213 d.58.49 YajQ-like
View Download 0.213 a.4.5 "Winged helix" DNA-binding domain
View Download 0.211 a.6.1 Putative DNA-binding domain
View Download 0.208 a.58.1 Chemotaxis receptor methyltransferase CheR, N-terminal domain
View Download 0.208 a.58.1 Chemotaxis receptor methyltransferase CheR, N-terminal domain
View Download 0.204 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.204 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.203 d.58.11 EF-G/eEF-2 domains III and V
View Download 0.202 d.58.1 4Fe-4S ferredoxins

Predicted Domain #4
Region A:
Residues: [327-409]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VAASHTKTIR TQSEAIEHIS SAISNGKASC YHILEEISSL PKYSSLDIDD LCSELIIKAK  60
   61 CTDDCKIVVK ARDLQSALVR QLL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.590 0.376 response to cadmium ion a.39.1 EF-hand
View Download 0.780 0.338 response to cadmium ion a.3.1 Cytochrome c
View Download 0.722 0.037 response to cadmium ion a.156.1 S13-like H2TH domain
View Download 0.512 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.480 N/A N/A c.3.1 FAD/NAD(P)-binding domain
View Download 0.469 N/A N/A a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.465 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.456 N/A N/A c.10.2 L domain-like
View Download 0.441 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.424 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.419 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.403 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.401 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.396 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.386 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.385 N/A N/A a.39.1 EF-hand
View Download 0.373 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.369 N/A N/A a.3.1 Cytochrome c
View Download 0.369 N/A N/A a.74.1 Cyclin-like
View Download 0.360 N/A N/A a.159.1 Protein serine/threonine phosphatase 2C, C-terminal domain
View Download 0.359 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.348 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.299 N/A N/A a.64.2 Bacteriocin AS-48
View Download 0.299 N/A N/A a.83.1 Guanido kinase N-terminal domain
View Download 0.298 N/A N/A a.39.1 EF-hand
View Download 0.298 N/A N/A a.81.1 N-terminal domain of DnaB helicase
View Download 0.288 N/A N/A a.159.2 FF domain
View Download 0.280 N/A N/A a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.276 N/A N/A a.4.1 Homeodomain-like
View Download 0.273 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.266 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.260 N/A N/A a.4.1 Homeodomain-like
View Download 0.260 N/A N/A a.4.1 Homeodomain-like
View Download 0.258 N/A N/A a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.256 N/A N/A a.159.2 FF domain
View Download 0.255 N/A N/A a.156.1 S13-like H2TH domain
View Download 0.251 N/A N/A a.39.1 EF-hand
View Download 0.245 N/A N/A a.101.1 Uteroglobin-like
View Download 0.244 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.241 N/A N/A a.65.1 Annexin
View Download 0.237 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.229 N/A N/A c.13.2 Anti-sigma factor antagonist SpoIIaa
View Download 0.223 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.218 N/A N/A d.55.1 Ribosomal protein L22
View Download 0.215 N/A N/A a.4.1 Homeodomain-like
View Download 0.213 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.202 N/A N/A a.156.1 S13-like H2TH domain
View Download 0.201 N/A N/A a.39.1 EF-hand


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle