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View Structure Prediction Details

Protein: YDR387C
Organism: Saccharomyces cerevisiae
Length: 555 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YDR387C.

Description E-value Query
Range		 Subject
Range
INT2_ARATH - Probable inositol transporter 2 OS=Arabidopsis thaliana GN=INT2 PE=1 SV=1
 0.0 [34..553] [23..568]
KHT2_KLULC - Hexose transporter 2 OS=Kluyveromyces lactis GN=KHT2 PE=3 SV=1
 3.0E-99 [2..552] [26..538]
gi|9652184 - gi|9652184|gb|AAF91431.1| putative Na+/myo-inositol symporter [Mesembryanthemum crystallinum]
 4.0E-98 [36..547] [24..564]
HXT4_YEAST - Low-affinity glucose transporter HXT4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HX...
HXT4 - High-affinity glucose transporter of the major facilitator superfamily, expression is induced by low...
 9.0E-97 [1..550] [32..543]

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Predicted Domain #1
Region A:
Residues: [1-221] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTDESEDVY SDLYSIISQV TSNTANDIEQ LPYALTFKTS LIFVGATIGG LLFGYDTGVI  60
   61 SGVLLSLKPE DLSLVVLTDV QKELITSSTS VGSFFGSILA FPLADRYGRR ITLAICCSIF 120
  121 ILAAIGMAIA RTLTFLICGR LLVGIAVGVS AQCVPLFLSE ISPSRIRGFM LTLNIIAITG 180
  181 GQLVSYVIAS LMKEIDNSWR YLFALSAIPA ILFLSILDFI P

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [266-530] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LRLYEDASEP LLVQSQSVIR YMDSSTSGTL SPPNIKRLSS NTERTSNTMS SSSAYLSALR  60
   61 GPAPNGALAS NKKKRHRMEP RTIRALIVGC MLMFFQQITG FNAFMYYAAI IFSKFNIKNP 120
  121 LLPPILIAST NFIFTFFAMY TMDSLGRRAI LLRTILIMTV GLLLCSVGFG HDQVNLLLIS 180
  181 VVIYVAAYAS AMGSVPWTCV EFLPLNRRSF GASCIACTNW LTNAFVSMTY LSTINTIGDE 240
  241 NTMLIFAFFT VCAWFFVYFW YPEVK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 248.29073
Match: 1ja5A_
Description: No description for 1ja5A_ was found.

Predicted functions:

Term Confidence Notes
alcohol transmembrane transporter activity 6.7545566917184 bayes_pls_golite062009
polyol transmembrane transporter activity 6.7545566917184 bayes_pls_golite062009
glycerol transmembrane transporter activity 6.54968363274124 bayes_pls_golite062009
glycerol-3-phosphate transmembrane transporter activity 5.40344495119017 bayes_pls_golite062009
transporter activity 4.09176719149278 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.54194478414824 bayes_pls_golite062009
hexose phosphate transmembrane transporter activity 3.29248638217469 bayes_pls_golite062009
glucose-6-phosphate transmembrane transporter activity 3.29248638217469 bayes_pls_golite062009
sugar:hydrogen symporter activity 2.99050613058546 bayes_pls_golite062009
cation:sugar symporter activity 2.99050613058546 bayes_pls_golite062009
carbohydrate transmembrane transporter activity 2.62141276633776 bayes_pls_golite062009
sugar transmembrane transporter activity 2.47557586092261 bayes_pls_golite062009
ion transmembrane transporter activity 2.21266150105753 bayes_pls_golite062009
solute:hydrogen symporter activity 2.10485633822652 bayes_pls_golite062009
cation transmembrane transporter activity 1.79369588808394 bayes_pls_golite062009
monosaccharide transmembrane transporter activity 1.6904339767429 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
binding 1.46605775041083 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [222-265] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESPRWSISKG DILYTRDSLR MLYPTASTYH VNSKIKQLII ELDK

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [531-555] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLSLEEVGRV FDNGIDVHYV FRTYH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 248.29073
Match: 1ja5A_
Description: No description for 1ja5A_ was found.
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle