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View Structure Prediction Details

Protein: EFT2, EFT1
Organism: Saccharomyces cerevisiae
Length: 842 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EFT2, EFT1.

Description E-value Query
Range
Subject
Range
Ef2b-PC, Ef2b-PA... - The gene Elongation factor 2b is referred to in FlyBase by the symbol Dmel\Ef2b (CG2238, FBgn0000559...
gi|220948442 - gi|220948442|gb|ACL86764.1| Ef2b-PA [synthetic construct]
0.0 [1..842] [1..844]
gi|15028587 - gi|15028587|gb|AAK77225.1| elongation factor 2 [Aedes aegypti]
0.0 [1..842] [1..844]
EF2_CHICK - Elongation factor 2 OS=Gallus gallus GN=EEF2 PE=1 SV=3
0.0 [1..842] [1..858]
EF2_PONAB - Elongation factor 2 OS=Pongo abelii GN=EEF2 PE=2 SV=3
EEF2 - eukaryotic translation elongation factor 2
EF2_PONPY - Elongation factor 2 - Pongo pygmaeus (Orangutan)
0.0 [1..842] [1..858]
EF2_MOUSE - Elongation factor 2 OS=Mus musculus GN=Eef2 PE=1 SV=2
gi|62871614 - gi|62871614|gb|AAH90153.1| Unknown (protein for MGC:98463) [Xenopus laevis]
0.0 [1..842] [1..858]
EF2_RAT - Elongation factor 2 OS=Rattus norvegicus GN=Eef2 PE=1 SV=4
0.0 [1..842] [1..858]
gi|600159 - gi|600159|gb|AAB60497.1| elongation factor 2 [Cricetulus griseus]
0.0 [1..842] [1..858]

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Predicted Domain #1
Region A:
Residues: [1-349]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVAFTVDQMR SLMDKVTNVR NMSVIAHVDH GKSTLTDSLV QRAGIISAAK AGEARFTDTR  60
   61 KDEQERGITI KSTAISLYSE MSDEDVKEIK QKTDGNSFLI NLIDSPGHVD FSSEVTAALR 120
  121 VTDGALVVVD TIEGVCVQTE TVLRQALGER IKPVVVINKV DRALLELQVS KEDLYQTFAR 180
  181 TVESVNVIVS TYADEVLGDV QVYPARGTVA FGSGLHGWAF TIRQFATRYA KKFGVDKAKM 240
  241 MDRLWGDSFF NPKTKKWTNK DTDAEGKPLE RAFNMFILDP IFRLFTAIMN FKKDEIPVLL 300
  301 EKLEIVLKGD EKDLEGKALL KVVMRKFLPA ADALLEMIVL HLPSPVTAQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1300.9691
Match: 1dar__
Description: Elongation factor G (EF-G), domain II; Elongation factor G (EF-G), N-terminal (G) domain; Elongation factor G (EF-G), domain IV; Elongation factor G (EF-G)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [350-516]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AYRAEQLYEG PADDANCIAI KNCDPKADLM LYVSKMVPTS DKGRFYAFGR VFAGTVKSGQ  60
   61 KVRIQGPNYV PGKKDDLFIK AIQRVVLMMG RFVEPIDDCP AGNIIGLVGI DQFLLKTGTL 120
  121 TTSETAHNMK VMKFSVSPVV QVAVEVKNAN DLPKLVEGLK RLSKSDP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1300.9691
Match: 1dar__
Description: Elongation factor G (EF-G), domain II; Elongation factor G (EF-G), N-terminal (G) domain; Elongation factor G (EF-G), domain IV; Elongation factor G (EF-G)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [517-842]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CVLTYMSESG EHIVAGTGEL HLEICLQDLE HDHAGVPLKI SPPVVAYRET VESESSQTAL  60
   61 SKSPNKHNRI YLKAEPIDEE VSLAIENGII NPRDDFKARA RIMADDYGWD VTDARKIWCF 120
  121 GPDGNGPNLV IDQTKAVQYL HEIKDSVVAA FQWATKEGPI FGEEMRSVRV NILDVTLHAD 180
  181 AIHRGGGQII PTMRRATYAG FLLADPKIQE PVFLVEIQCP EQAVGGIYSV LNKKRGQVVS 240
  241 EEQRPGTPLF TVKAYLPVNE SFGFTGELRQ ATGGQAFPQM VFDHWSTLGS DPLDPTSKAG 300
  301 EIVLAARKRH GMKEEVPGWQ EYYDKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1300.9691
Match: 1dar__
Description: Elongation factor G (EF-G), domain II; Elongation factor G (EF-G), N-terminal (G) domain; Elongation factor G (EF-G), domain IV; Elongation factor G (EF-G)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle