YRC Public Data Repository - Protein Structure Prediction

Protein:	SRB7
Organism:	Saccharomyces cerevisiae
Length:	140 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SRB7.

Description	E-value	Query Range	Subject Range
gi\|25407290, gi\|... - gi\|7267236\|emb\|CAB80843.1\| hypothetical protein [Arabidopsis thaliana], pir\|\|B85060 hypothetical pro...	181.0	[0..3]	[138..244]
gi\|61680697, gi\|... - gi\|61680697\|pdb\|1YKE\|D Chain D, Structure Of The Mediator Med7MED21 SUBCOMPLEX, gi\|61680695\|pdb\|1YKE...	165.0	[0..1]	[140..1]
gi\|50729132 - gi\|50729132\|ref\|XP_416442.1\| PREDICTED: similar to SRB7 suppressor of RNA polymerase B homolog; RNA ...	153.0	[0..1]	[139..191]
MED21_SCHPO - Mediator of RNA polymerase II transcription subunit 21 OS=Schizosaccharomyces pombe (strain 972 / AT... srb7 - mediator complex subunit Srb7	153.0	[0..1]	[129..1]
gi\|55667209 - gi\|55667209\|ref\|XP_520809.1\| PREDICTED: SRB7 suppressor of RNA polymerase B homolog isoform 2 [Pan t...	138.0	[0..1]	[139..1]
gi\|1515377 - gi\|1515377\|gb\|AAB06944.1\| RNA polymerase II complex component SRB7 [Homo sapiens]	138.0	[0..1]	[139..1]
MED21_MOUSE - Mediator of RNA polymerase II transcription subunit 21 OS=Mus musculus GN=Med21 PE=1 SV=1	137.0	[0..1]	[139..1]

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Predicted Domain #1

Region A:
Residues: [1-140]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDRLTQLQI CLDQMTEQFC ATLNYIDKNH GFERLTVNEP QMSDKHATVV PPEEFSNTID  60
   61 ELSTDIILKT RQINKLIDSL PGVDVSAEEQ LRKIDMLQKK LVEVEDEKIE AIKKKEKLLR 120
  121 HVDSLIEDFV DGIANSKKST

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	41.39794
Match:	1ykeB
Description:	Structure of the mediator MED7/MED21 subcomplex
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits