YRC Public Data Repository - Protein Structure Prediction

Protein:	SUR2
Organism:	Saccharomyces cerevisiae
Length:	349 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SUR2.

Description	E-value	Query Range	Subject Range
SUR2_YEAST - Sphingolipid C4-hydroxylase SUR2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SUR2 PE... SUR2 - Sphinganine C4-hydroxylase, catalyses the conversion of sphinganine to phytosphingosine in sphingoli...	4.0E-83	[1..349]	[1..349]
ERG3_CANGA - Delta(7)-sterol 5(6)-desaturase OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 06... ERG3_CANGA - C-5 sterol desaturase OS=Candida glabrata GN=ERG3 PE=3 SV=1	1.0E-55	[3..337]	[42..360]
SBH2_ARATH - Sphinganine C4-monooxygenase 2 OS=Arabidopsis thaliana GN=SBH2 PE=1 SV=1	2.0E-50	[46..307]	[6..244]
SPBC887.15c - sphingosine hydroxylase SUR2_SCHPO - Sphingolipid C4-hydroxylase sur2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=sur2 PE=3...	4.0E-50	[46..306]	[11..279]
ERG3_CANAX - Delta(7)-sterol 5(6)-desaturase OS=Candida albicans GN=ERG3 PE=3 SV=1 gi\|238879059 - gi\|238879059\|gb\|EEQ42697.1\| C-5 sterol desaturase [Candida albicans WO-1]	2.0E-47	[32..333]	[100..383]
MSMO1_RAT - Methylsterol monooxygenase 1 OS=Rattus norvegicus GN=Msmo1 PE=2 SV=1	7.0E-47	[11..317]	[8..293]

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Predicted Domain #1

Region A:
Residues: [1-349]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNVTSNATAA GSFPLAFGLK TSFGFMHYAK APAINLRPKE SLLPEMSDGV LALVAPVVAY  60
   61 WALSGIFHVI DTFHLAEKYR IHPSEEVAKR NKASRMHVFL EVILQHIIQT IVGLIFMHFE 120
  121 PIYMTGFEEN AMWKLRADLP RIIPDAAIYY GYMYGMSALK IFAGFLFVDT WQYFLHRLMH 180
  181 MNKTLYKWFH SVHHELYVPY AYGALFNNPV EGFLLDTLGT GIAMTLTHLT HREQIILFTF 240
  241 ATMKTVDDHC GYALPLDPFQ WLFPNNAVYH DIHHQQFGIK TNFAQPFFTF WDNLFQTNFK 300
  301 GFEEYQKKQR RVTIDKYKEF LQERELEKKE KLKNFKAMNA AENEVKKEK

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	90.619789
Match:	PF01598
Description:	Sterol desaturase

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [120-258]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPIYMTGFEE NAMWKLRADL PRIIPDAAIY YGYMYGMSAL KIFAGFLFVD TWQYFLHRLM  60
   61 HMNKTLYKWF HSVHHELYVP YAYGALFNNP VEGFLLDTLG TGIAMTLTHL THREQIILFT 120
  121 FATMKTVDDH CGYALPLDP

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	18.431798
Match:	PF04116.4
Description:	No description for PF04116.4 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [259-349]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FQWLFPNNAV YHDIHHQQFG IKTNFAQPFF TFWDNLFQTN FKGFEEYQKK QRRVTIDKYK  60
   61 EFLQERELEK KEKLKNFKAM NAAENEVKKE K

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.02
Match:	1sg7A
Description:	NMR solution structure of the putative cation transport regulator ChaB
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits