YRC Public Data Repository - Protein Structure Prediction

Protein:	AMD2
Organism:	Saccharomyces cerevisiae
Length:	549 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AMD2.

Description	E-value	Query Range	Subject Range
AMD2 - Putative amidase AMDY_YEAST - Probable amidase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AMD2 PE=3 SV=2	0.0	[1..549]	[1..549]
gi\|18478410 - gi\|18478410\|dbj\|BAB84516.1\| acetamidase [Monascus purpureus]	0.0	[3..545]	[1..538]
AMDS_EMENI - Acetamidase OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) GN=a... gi\|62467026 - gi\|62467026\|gb\|AAX83680.1\| acetamidase [Expression vector pKLAC1] AMDS_EMENI - Acetamidase OS=Emericella nidulans GN=amdS PE=2 SV=1 gi\|158536734 - gi\|158536734\|gb\|ABW72883.1\| acetamidase [Expression vector pKLAC2] gi\|209403504 - gi\|209403504\|gb\|ACI46132.1\| acetamidase [Expression vector pKLMF-EK] gi\|209403509 - gi\|209403509\|gb\|ACI46136.1\| acetamidase [Expression vector pKLMF-FX] gi\|209403512 - gi\|209403512\|gb\|ACI46138.1\| acetamidase [Expression vector pKLAC1-Gluc]	0.0	[3..549]	[1..542]
gi\|13569691, gi\|... - gi\|13569691\|gb\|AAK31197.1\|AF349512_1 general amidase-B [Aspergillus niger], gi\|134077537\|emb\|CAK9668... gi\|145240733 - gi\|145240733\|ref\|XP_001393013.1\| general amidase gmdB-Aspergillus niger	0.0	[1..549]	[1..549]
GATA1_CLOAB - Glutamyl-tRNA(Gln) amidotransferase subunit A 1 OS=Clostridium acetobutylicum (strain ATCC 824 / DSM... GATA1_CLOAB, GAA... - Glutamyl-tRNA(Gln) amidotransferase subunit A 1 OS=Clostridium acetobutylicum GN=gatA1 PE=3 SV=1, (Q...	0.0	[57..547]	[2..474]
gi\|13517937 - gi\|13517937\|gb\|AAK29061.1\|AF348620_1 acetamidase [Emericella rugulosa]	0.0	[3..545]	[1..538]
gi\|13569685 - gi\|13569685\|gb\|AAK31194.1\|AF349509_1 acetamidase-B [Aspergillus ustus]	0.0	[3..545]	[1..536]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[4..549]	[3..543]

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Predicted Domain #1

Region A:
Residues: [1-549]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVHSTWKEK VQLKKDQLNS KIKDEWKLNS TTITRLKNDK KNLIKNIDDL CSSSENQITH  60
   61 STIMALRQAL EAKELSCHEI TAAFCHRAAL IHQVVNCLSE IMFSEALRLA DYYDSNRPAI 120
  121 LPPLYGIPIS LKDQCNVEGV DTSLGYLCRT FKPKTKNEES LIVSFLRDLG AIIFVKTTVP 180
  181 SSMMATDTQS NTFGYTYNSI NLSFSSGGSS GGEGSLIGAH GSLLGLGTDI GGSIRIPSSY 240
  241 QGLFGLKPTF GRVPYLRVDN SFEGRETIPS VIGPLARDLS DLRYFMSCVI NICQPWVQDV 300
  301 KCIPYHFDSS TSKLHDNYVV GIWYGDGVID PPPSDIRALK TCEDLVNKTK GMKAVKWEPS 360
  361 SELSRELFDL ANEADVADSG NEIKNEFEIS GEPLLDILKP MVLENGRPPY TVNEWWDLTK 420
  421 RVYNAQQLMR DYYLSFPESE RPDVIISPTT LMPFRPGDML KTTLRYILLF NVLNFPSLSI 480
  481 PVGSVDCQID GLMDTTSALN PEDKMIKTYW NDLIQSGEID GFPIGLQVVS PTFNDNEVCK 540
  541 FASWLFSKI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	107.0
Match:	1gr8A_
Description:	No description for 1gr8A_ was found.

Predicted functions:

Term	Confidence	Notes
fatty acid amide hydrolase activity	1.00789760760064	bayes_pls_golite062009
hydrolase activity	0.989553693425583	bayes_pls_golite062009
catalytic activity	0.906509857495572	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: