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View Structure Prediction Details

Protein: IVY1
Organism: Saccharomyces cerevisiae
Length: 453 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IVY1.

Description E-value Query
Range
Subject
Range
IVY1 - Phospholipid-binding protein that interacts with both Ypt7p and Vps33p, may partially counteract the...
IVY1_YEAST - Protein IVY1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=IVY1 PE=1 SV=1
gi|151942207 - gi|151942207|gb|EDN60563.1| protein interacting with Vps33p and Ypt7p [Saccharomyces cerevisiae YJM7...
gi|190404820 - gi|190404820|gb|EDV08087.1| protein IVY1 [Saccharomyces cerevisiae RM11-1a]
0.0 [1..453] [1..453]
gi|85114181 - gi|85114181|ref|XP_964648.1| hypothetical protein ( (AL442164) conserved hypothetical protein [Neuro...
gi|28926438, gi|... - gi|32417476|ref|XP_329216.1| hypothetical protein ( (AL442164) conserved hypothetical protein [Neuro...
0.0 [65..325] [11..332]

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Predicted Domain #1
Region A:
Residues: [1-91]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPDNNTEQLQ GSPSSDQRLR VDWDNGNHFD VSPDRYAPHL SEFYPIVNSK RPVASSAGSE  60
   61 NNDHLDDMNH LRSSKVYSKA RRASSITSGT S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.520 d.15.1 Ubiquitin-like
View Download 0.213 a.39.1 EF-hand
View Download 0.268 d.58.7 RNA-binding domain, RBD
View Download 0.247 d.109.1 Actin depolymerizing proteins
View Download 0.289 d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.520 d.15.1 Ubiquitin-like
View Download 0.289 d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.268 d.58.7 RNA-binding domain, RBD
View Download 0.247 d.109.1 Actin depolymerizing proteins
View Download 0.213 a.39.1 EF-hand
View Download 0.212 d.26.1 FKBP-like
View Download 0.209 c.55.7 Methylated DNA-protein cysteine methyltransferase domain
View Download 0.208 c.103.1 Hypothetical protein MT938 (MTH938)

Predicted Domain #2
Region A:
Residues: [92-325]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TINDLQTLIT KRDVKETQEA LSTLLRNSNA YSDSLLKTSQ NGAEIAHSLE NIAKLKGCND  60
   61 ETAEKLLSAS GLFYLLSNHQ LIMSKYFNDL LGDNLIDDID EFELQTKIME NKFKAQSKEQ 120
  121 SLKLKLQERH NFDISKRKIR NLISYRESLS SLQARLDQLE TLKHDFYMDS YELVENTCNK 180
  181 VLSKVATVSR AQVEISENIA RKGWSGGGLD ELLCDADDPF SKKADGPYGT IGGD

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.38
Match: 1i49A
Description: Arfaptin, Rac-binding fragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [326-453]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GETAGEAYNS DEETGGNDVV LNELLEGTSQ PSTSKTSLPK SKGSSTVSTP NHSQSSSNKD  60
   61 GVRNNGGGKN GEDEDTDNLM GTENSFSLPP TRNSAEETTQ TFKQLSIKED NDNHSSDTDG 120
  121 MQDQSSNI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.362 a.74.1 Cyclin-like
View Download 0.358 f.14.1 Voltage-gated potassium channels
View Download 0.362 a.74.1 Cyclin-like
View Download 0.358 f.14.1 Voltage-gated potassium channels


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